Why Does the Intestine Lack Basolateral Efflux Transporters for Cationic Compounds? A Provocative Hypothesis (Q38730627)

5 September 2017

Why Does the Intestine Lack Basolateral Efflux Transporters for Cationic Compounds? A Provocative Hypothesis (English)

1 reference

5 September 2017

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26869413%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

author name string

William R Proctor

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26869413%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Xin Ming

2

1 reference

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12 June 2020

David Bourdet

3

1 reference

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12 June 2020

Tianxiang Kevin Han

4

1 reference

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12 June 2020

Dhiren R Thakker

6

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12 June 2020

language of work or name

English

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publication date

1 February 2016

1 reference

Journal of Pharmaceutical Sciences

5 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26869413%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

volume

105

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12 June 2020

page(s)

484-496

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12 June 2020

issue

2

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Occludin: one protein, many forms

12 June 2020

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Identification and functional characterization of a new human kidney-specific H+/organic cation antiporter, kidney-specific multidrug and toxin extrusion 2.

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A human transporter protein that mediates the final excretion step for toxic organic cations

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Identification and characterization of a novel monoamine transporter in the human brain

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Prediction and validation of enzyme and transporter off-targets for metformin.

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Mechanisms for membrane transport of metformin in human intestinal epithelial Caco-2 cells

7 January 2021

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Intestinal absorptive transport of the hydrophilic cation ranitidine: a kinetic modeling approach to elucidate the role of uptake and efflux transporters and paracellular vs. transcellular transport in Caco-2 cells.

7 January 2021

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Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells

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Claudin extracellular domains determine paracellular charge selectivity and resistance but not tight junction fibril architecture

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Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca2+ absorption between enterocytes.

7 January 2021

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The density of small tight junction pores varies among cell types and is increased by expression of claudin-2.

7 January 2021

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Regional levels of drug transporters along the human intestinal tract: co-expression of ABC and SLC transporters and comparison with Caco-2 cells

7 January 2021

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Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

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Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2.

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