Autophagy in acute leukemias: a double-edged sword with important therapeutic implications (Q26828544)

Camilla Evangelisti

2

0 references

Francesca Buontempo

Francesca Buontempo

5

0 references

Annalisa Lonetti

Annalisa Lonetti

4

0 references

James A. McCubrey

James A. McCubrey

7

0 references

author name string

Cecilia Evangelisti

1

1 reference

Luca M. Neri

6

1 reference

Alberto M. Martelli

8

1 reference

language of work or name

1 reference

January 2015

1 reference

Biochimica et Biophysica Acta

published in

1 reference

volume

1853

1 reference

issue

1

1 reference

page(s)

14-26

1 reference

Autophagic control of cell 'stemness'.

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Myelodysplastic syndrome hematopoietic stem cell

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The hematopoietic stem cell niche: low in oxygen but a nice place to be.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Preclinical testing of the Akt inhibitor triciribine in T-cell acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Concise review: genetic dissection of hypoxia signaling pathways in normal and leukemic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy of mitochondria in rat bone marrow erythroid cells. Relation to nuclear extrusion.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Oxidative stress and the myelodysplastic syndromes

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Microautophagy: lesser-known self-eating

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Tightrope act: autophagy in stem cell renewal, differentiation, proliferation, and aging.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy and tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Comparative study of autophagy inhibition by 3MA and CQ on Cytarabine‑induced death of leukaemia cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Mammalian target of rapamycin as a target in hematological malignancies

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Blastic leukaemias (AML): a biologist's view

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Regulation of autophagy by Forkhead box (FOX) O transcription factors.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy in neurodegeneration and development

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Anti- and pro-tumor functions of autophagy

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy contributes to dasatinib-induced myeloid differentiation of human acute myeloid leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

LC3 conjugation system in mammalian autophagy

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The epigenetic landscape of T-cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Recruitment of RXR by Homotetrameric RARα Fusion Proteins Is Essential for Transformation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Mammalian autophagy: core molecular machinery and signaling regulation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The Beclin 1 interactome

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The protein-vesicle network of autophagy

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy in the Pathogenesis of Disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Hematopoiesis: an evolving paradigm for stem cell biology

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy suppresses tumorigenesis through elimination of p62

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Mitochondria supply membranes for autophagosome biogenesis during starvation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy: renovation of cells and tissues

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

To be or not to be? How selective autophagy and cell death govern cell fate

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Akt-dependent and -independent mechanisms of mTOR regulation in cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Ubiquitination and phosphorylation of Beclin 1 and its binding partners: Tuning class III phosphatidylinositol 3-kinase activity and tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

ATF4 activation by the p38MAPK-eIF4E axis mediates apoptosis and autophagy induced by selenite in Jurkat cells.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Regulation of autophagy: modulation of the size and number of autophagosomes

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Iron chelators induce autophagic cell death in multiple myeloma cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy and the integrated stress response

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy in tumour cell death

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Molecular mechanisms of regulated necrosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Foxo3a is essential for maintenance of the hematopoietic stem cell pool.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

High glucose induces autophagy in podocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Retinoid receptor signaling and autophagy in acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Idarubicin induces mTOR-dependent cytotoxic autophagy in leukemic cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Cell death by autophagy: facts and apparent artefacts

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

GX15-070 (obatoclax) overcomes glucocorticoid resistance in acute lymphoblastic leukemia through induction of apoptosis and autophagy

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy is required for self-renewal and differentiation of adult human stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Chaperone-mediated autophagy: roles in disease and aging

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Erythroid precursors from patients with low-risk myelodysplasia demonstrate ultrastructural features of enhanced autophagy of mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

HMGB1-induced autophagy promotes chemotherapy resistance in leukemia cells.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

MicroRNAs in acute leukemia: from biological players to clinical contributors

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

AMP-dependent kinase/mammalian target of rapamycin complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Dexamethasone versus prednisone for induction therapy in childhood acute lymphoblastic leukemia: a systematic review and meta-analysis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Cytotoxic activity of the novel Akt inhibitor, MK-2206, in T-cell acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Targeting the PI3K/Akt/mTOR signaling pathway in B-precursor acute lymphoblastic leukemia and its therapeutic potential.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Novel TAL1 targets beyond protein-coding genes: identification of TAL1-regulated microRNAs in T-cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy fights disease through cellular self-digestion

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy in immunity and inflammation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

FOXO3A directs a protective autophagy program in haematopoietic stem cells.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Eaten alive: a history of macroautophagy

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Selective autophagy: ubiquitin-mediated recognition and beyond

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Plasma membrane contributes to the formation of pre-autophagosomal structures

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Emerging regulation and functions of autophagy

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Acute promyelocytic leukaemia: novel insights into the mechanisms of cure

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy--a key player in cellular and body metabolism

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Molecular pathogenesis of T-cell leukaemia and lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Dynamics and diversity in autophagy mechanisms: lessons from yeast

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy is essential to suppress cell stress and to allow BCR-Abl-mediated leukemogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

A JNK-mediated autophagy pathway that triggers c-IAP degradation and necroptosis for anticancer chemotherapy.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Frequent elevation of Akt kinase phosphorylation in blood marrow and peripheral blood mononuclear cells from high-risk myelodysplastic syndrome patients

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The serine/threonine kinase ULK1 is a target of multiple phosphorylation events.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The kinase triad, AMPK, mTORC1 and ULK1, maintains energy and nutrient homoeostasis

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Inhibition of autophagy abrogates tumour necrosis factor alpha induced apoptosis in human T-lymphoblastic leukaemic cells.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Retinoic acid and arsenic trioxide for acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

NIX is required for programmed mitochondrial clearance during reticulocyte maturation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy is a critical mechanism for the induction of the antileukemic effects of arsenic trioxide

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Human light chain 3/MAP1LC3B is cleaved at its carboxyl-terminal Met121 to expose Gly120 for lipidation and targeting to autophagosomal membranes

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

A critical role for the autophagy gene Atg5 in T cell survival and proliferation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Synergy against PML-RARa: targeting transcription, proteolysis, differentiation, and self-renewal in acute promyelocytic leukemia.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Regulation and function of uncoordinated-51 like kinase proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy suppresses tumor progression by limiting chromosomal instability

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Anthracyclines during induction therapy in acute myeloid leukaemia: a systematic review and meta-analysis

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Prognostic factors for acute myeloid leukaemia in adults--biological significance and clinical use.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Targeting survival pathways in chronic myeloid leukaemia stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Proposals for the Classification of the Acute Leukaemias French-American-British (FAB) Co-operative Group

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Temsirolimus, an mTOR inhibitor, in combination with lower-dose clofarabine as salvage therapy for older patients with acute myeloid leukaemia: results of a phase II GIMEMA study (AML-1107)

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Glucocorticoid resistance in paediatric acute lymphoblastic leukaemia.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy and cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Identification of the constant chromosome regions involved in human hematologic malignant disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy driven by a master regulator of hematopoiesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Regulation mechanisms and signaling pathways of autophagy

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Regulation of mammalian autophagy in physiology and pathophysiology.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Constitutive activation of Akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The Akt/mammalian target of rapamycin signal transduction pathway is activated in high-risk myelodysplastic syndromes and influences cell survival and proliferation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Mixed lineage leukemia translocations and a leukemia stem cell program

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Activity of the novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 against T-cell acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The double-edged sword of autophagy modulation in cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The combination of a histone deacetylase inhibitor with the Bcl-2 homology domain-3 mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagy

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Preclinical and early clinical evaluation of the oral AKT inhibitor, MK-2206, for the treatment of acute myelogenous leukemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy is a survival mechanism of acute myelogenous leukemia precursors during dual mTORC2/mTORC1 targeting

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The molecular basis of T cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The roles of FLT3 in hematopoiesis and leukemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Constitutive phosphoinositide 3-kinase/Akt activation represents a favorable prognostic factor in de novo acute myelogenous leukemia patients.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Treatment and prognostic impact of transient leukemia in neonates with Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

FoxO3a regulates hematopoietic homeostasis through a negative feedback pathway in conditions of stress or aging

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The NAD biosynthesis inhibitor APO866 has potent antitumor activity against hematologic malignancies

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Microarray-based classifiers and prognosis models identify subgroups with distinct clinical outcomes and high risk of AML transformation of myelodysplastic syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy contributes to therapy-induced degradation of the PML/RARA oncoprotein

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Acute leukemia incidence and patient survival among children and adults in the United States, 2001-2007.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Inhibition of Bcl-2 antiapoptotic members by obatoclax potently enhances sorafenib-induced apoptosis in human myeloid leukemia cells through a Bim-dependent process

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagic degradation of the BCR-ABL oncoprotein and generation of antileukemic responses by arsenic trioxide

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Potent obatoclax cytotoxicity and activation of triple death mode killing across infant acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Pediatric acute lymphoblastic leukemia: where are we going and how do we get there?

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Targeting autophagy potentiates the apoptotic effect of histone deacetylase inhibitors in t(8;21) AML cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Asparaginase unveils glutamine-addicted AML.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Transient receptor potential vanilloid 1 activation induces autophagy in thymocytes through ROS-regulated AMPK and Atg4C pathways.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The leukemia-specific fusion gene ETV6/RUNX1 perturbs distinct key biological functions primarily by gene repression

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

C22:0- and C24:0-dihydroceramides confer mixed cytotoxicity in T-cell acute lymphoblastic leukemia cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Differential effects of selective inhibitors targeting the PI3K/AKT/mTOR pathway in acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

mTOR inhibition by everolimus in childhood acute lymphoblastic leukemia induces caspase-independent cell death

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

5-Azacytidine for the treatment of myelodysplastic syndromes.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Targeting the liver kinase B1/AMP-activated protein kinase pathway as a therapeutic strategy for hematological malignancies

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The phosphatidylinositol 3-kinase/Akt/mTOR signaling network as a therapeutic target in acute myelogenous leukemia patients.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

A combination of temsirolimus, an allosteric mTOR inhibitor, with clofarabine as a new therapeutic option for patients with acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

How recent advances in high-risk myelodysplastic syndrome physiopathology may impact future treatments.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Emerging treatments in acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Myelodysplastic syndromes in the United States: an update for clinicians

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Cancer statistics, 2010

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Therapeutic potential of targeting mTOR in T-cell acute lymphoblastic leukemia (review).

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy is essential for mitochondrial clearance in mature T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

A role for autophagic protein beclin 1 early in lymphocyte development

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The Interplay between Autophagy and Aging

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Dissecting the role of the Atg12-Atg5-Atg16 complex during autophagosome formation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy in stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy facilitates organelle clearance during differentiation of human erythroblasts: evidence for a role for ATG4 paralogs during autophagosome maturation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Dual inhibition of autophagy and the AKT pathway in prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Mitophagy in hematopoietic stem cells: the case for exploration

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

ATG13: just a companion, or an executor of the autophagic program?

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Phase I trial of hydroxychloroquine with dose-intense temozolomide in patients with advanced solid tumors and melanoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Combined MTOR and autophagy inhibition: phase I trial of hydroxychloroquine and temsirolimus in patients with advanced solid tumors and melanoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Combined autophagy and HDAC inhibition: a phase I safety, tolerability, pharmacokinetic, and pharmacodynamic analysis of hydroxychloroquine in combination with the HDAC inhibitor vorinostat in patients with advanced solid tumors

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Combined autophagy and proteasome inhibition: a phase 1 trial of hydroxychloroquine and bortezomib in patients with relapsed/refractory myeloma

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Outcome of early clinical trials of the combination of hydroxychloroquine with chemotherapy in cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

HMGB1-dependent and -independent autophagy

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

How shall I eat thee?

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

The autophagy gene ATG5 plays an essential role in B lymphocyte development

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Identification of Atg5-dependent transcriptional changes and increases in mitochondrial mass in Atg5-deficient T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

RAD001 (Everolimus) induces autophagy in acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

ATRA-induced upregulation of Beclin 1 prolongs the life span of differentiated acute promyelocytic leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

PML-RARα enhances constitutive autophagic activity through inhibiting the Akt/mTOR pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy regulates myeloid cell differentiation by p62/SQSTM1-mediated degradation of PML-RARα oncoprotein

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

FTY720 produces caspase-independent cell death of acute lymphoblastic leukemia cells.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Autophagy in the pathogenesis of myelodysplastic syndrome and acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

Azacitidine-resistant SKM1 myeloid cells are defective for AZA-induced mitochondrial apoptosis and autophagy.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAMCR.2014.09.023

7 January 2021

10.1016/J.BBAMCR.2014.09.023

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

25284725

1 reference

Consolidated OpenCitations Corpus – April 2017