Epigenetic protein families: a new frontier for drug discovery (Q29616621)

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28 January 2020

title

Epigenetic protein families: a new frontier for drug discovery (English)

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28 January 2020

author name string

Chas Bountra

2

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28 January 2020

Paul V Fish

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28 January 2020

Kevin Lee

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28 January 2020

Matthieu Schapira

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30 April 2017

publication date

13 April 2012

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Nature Reviews Drug Discovery

28 January 2020

published in

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28 January 2020

volume

11

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28 January 2020

page(s)

384-400

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28 January 2020

issue

5

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Epigenetics and the biological definition of gene x environment interactions

28 January 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Endocrine disruptor vinclozolin induced epigenetic transgenerational adult-onset disease

31 March 2020

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31 March 2020

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Epigenetics: Unravelling the cancer code

31 March 2020

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Molecular analysis of a multistep lung cancer model induced by chronic inflammation reveals epigenetic regulation of p16 and activation of the DNA damage response pathway

31 March 2020

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Chemogenetic analysis of human protein methyltransferases

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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The novel inhibitor of histone deacetylase resminostat (RAS2410) inhibits proliferation and induces apoptosis in multiple myeloma (MM) cells

31 March 2020

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Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat).

31 March 2020

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Discovery of (2E)-3-{2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl}-N-hydroxyacrylamide (SB939), an orally active histone deacetylase inhibitor with a superior preclinical profile

31 March 2020

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SB939, a novel potent and orally active histone deacetylase inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer.

31 March 2020

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CUDC-101, a multitargeted inhibitor of histone deacetylase, epidermal growth factor receptor, and human epidermal growth factor receptor 2, exerts potent anticancer activity

31 March 2020

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PCI-24781, a Novel Hydroxamic Acid HDAC Inhibitor, Exerts Cytotoxicity and Histone Alterations via Caspase-8 and FADD in Leukemia Cells

31 March 2020

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The novel deacetylase inhibitor AR-42 demonstrates pre-clinical activity in B-cell malignancies in vitro and in vivo

31 March 2020

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A novel histone deacetylase inhibitor, CG200745, potentiates anticancer effect of docetaxel in prostate cancer via decreasing Mcl-1 and Bcl-XL.

31 March 2020

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Abnormal histone modification patterns in lupus CD4+ T cells

31 March 2020

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12 December 2020

Pharmacodynamic response and inhibition of growth of human tumor xenografts by the novel histone deacetylase inhibitor PXD101.

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Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo

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12 December 2020

DNA methylation and cancer

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SMART, a simple modular architecture research tool: identification of signaling domains

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Histone acetylation and an epigenetic code

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HDAC Inhibitors--CHI's Third Annual Conference.

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28 January 2020

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