Acute neurodegeneration and the inflammasome: central processor for danger signals and the inflammatory response? (Q37062902)

18 August 2017

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title

Acute neurodegeneration and the inflammasome: central processor for danger signals and the inflammatory response? (English)

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18 August 2017

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1

George Trendelenburg

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author name string

George Trendelenburg

series ordinal

1

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18 August 2017

23 January 2008

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Journal of Cerebral Blood Flow & Metabolism

18 August 2017

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18 August 2017

28

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18 August 2017

5

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18 August 2017

867-881

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CDP-choline significantly restores phosphatidylcholine levels by differentially affecting phospholipase A2 and CTP: phosphocholine cytidylyltransferase after stroke

18 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Recent advances in crystal-induced acute inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Toll-like receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The apoptotic signaling pathway activated by Toll-like receptor-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Interleukin-1 and neuronal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Toll-like receptor 2 signaling in response to brain injury: an innate bridge to neuroinflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Pyrin-only protein 2 modulates NF-kappaB and disrupts ASC:CLR interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The antimicrobial peptide rCRAMP is present in the central nervous system of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Infiltrating CD14+ monocytes and expression of CD14 by activated parenchymal microglia/macrophages contribute to the pool of CD14+ cells in ischemic brain lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Uric acid is a risk factor for myocardial infarction and stroke: the Rotterdam study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Differential regulation of Toll-like receptor mRNAs in experimental murine central nervous system infections.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Cultured astrocytes express toll-like receptors for bacterial products.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Targeting IL-1 in inflammatory disease: new opportunities for therapeutic intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Pathophysiology of cerebral ischemia and brain trauma: similarities and differences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Identification of soluble CD14 as an endogenous agonist for Toll-like receptor 2 on human astrocytes by genome-scale functional screening of glial cell derived proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Toll-like receptor 3 on adult human astrocytes triggers production of neuroprotective mediators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Broad expression of Toll-like receptors in the human central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Reduced cerebral ischemia-reperfusion injury in Toll-like receptor 4 deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Negative regulation of toll-like receptor signaling by NF-kappaB p50 ubiquitination blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Identification of a key pathway required for the sterile inflammatory response triggered by dying cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The class B scavenger receptor CD36 mediates free radical production and tissue injury in cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Pathological role of Toll-like receptor signaling in cerebral malaria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Nucleic acid-sensing TLRs as modifiers of autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

In stroke, complement will get you nowhere.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Innate recognition of intracellular bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Blocking IL-1 in systemic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Pathobiology of ischaemic stroke: an integrated view

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Ischemic tolerance and endogenous neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Cellular pyrin domain-only protein 2 is a candidate regulator of inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

"Eat me" and "don't eat me" signals govern the innate immune response and tissue repair in the CNS: emphasis on the critical role of the complement system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

A randomised phase II study of interleukin-1 receptor antagonist in acute stroke patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The P2X7 receptor: a key player in IL-1 processing and release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Ischemic preconditioning increases antioxidants in the brain and peripheral organs after cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Induction of human beta-defensin-2 expression in human astrocytes by lipopolysaccharide and cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Attenuation of transient focal cerebral ischemic injury in transgenic mice expressing a mutant ICE inhibitory protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

CD36 is a sensor of diacylglycerides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

TLR2 mediates neuroinflammation and neuronal damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Pathophysiology and therapy of experimental stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Serum uric acid and risk of ischemic stroke: the ARIC Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Neuronal protection in stroke by an sLex-glycosylated complement inhibitory protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

NOD-LRR proteins: role in host-microbial interactions and inflammatory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

mRNA is an endogenous ligand for Toll-like receptor 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Inhibition of toll-like receptor and cytokine signaling--a unifying theme in ischemic tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

P2X receptors as cell-surface ATP sensors in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Toll-like receptors in central nervous system glial inflammation and homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Caspase-1 inflammasomes in infection and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Intracellular trafficking in neurones and glia of fibroblast growth factor-2, fibroblast growth factor receptor 1 and heparan sulphate proteoglycans in the injured adult rat cerebral cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Identification of a specific interleukin 1 inhibitor in the urine of febrile patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Negative regulation of toll-like receptor-mediated immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Toll-like receptor 4 gene C119A but not Asp299Gly polymorphism is associated with ischemic stroke among ethnic Chinese in Taiwan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Expression of NALP1 in cerebellar granule neurons stimulates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The role of inflammation in CNS injury and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Small self-RNA generated by RNase L amplifies antiviral innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Cryopyrin activates the inflammasome in response to toxins and ATP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Gout-associated uric acid crystals activate the NALP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Inflammatory caspases and inflammasomes: master switches of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

ASC is an activating adaptor for NF-kappa B and caspase-8-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Murine ortholog of ASC, a CARD-containing protein, self-associates and exhibits restricted distribution in developing mouse embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The danger model: a renewed sense of self

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Friendly and dangerous signals: is the tissue in control?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Viruses selectively upregulate Toll-like receptors in the central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Intracellular pattern recognition receptors in the host response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Expression and distribution of Toll-like receptors in the brain during murine neurocysticercosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Critical role of toll-like receptors and nucleotide oligomerisation domain in the regulation of health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Transforming growth factor-beta differentially inhibits MyD88-dependent, but not TRAM- and TRIF-dependent, lipopolysaccharide-induced TLR4 signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Nucleotide-binding oligomerization domain-2 modulates specific TLR pathways for the induction of cytokine release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Tissue-specific mRNA expression profiles of human toll-like receptors and related genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The inflammasome: first line of the immune response to cell stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Cell wall-mediated neuronal damage in early sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Distinct roles of TLR2 and the adaptor ASC in IL-1beta/IL-18 secretion in response to Listeria monocytogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The death domain superfamily in intracellular signaling of apoptosis and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

RICK/RIP2 Mediates Innate Immune Responses Induced through Nod1 and Nod2 but Not TLRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Neuroprotective actions of endogenous interleukin-1 receptor antagonist (IL-1ra) are mediated by glia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Oxidative stress generated by hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The TLR-7 agonist, imiquimod, enhances dendritic cell survival and promotes tumor antigen-specific T cell priming: relation to central nervous system antitumor immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Toll-like receptors modulate adult hippocampal neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Uric acid reduces brain damage and improves the benefits of rt-PA in a rat model of thromboembolic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Caspase-1 builds a new barrier to infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Reduced ischemic brain injury in interleukin-1 beta converting enzyme-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Molecular identification of a danger signal that alerts the immune system to dying cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

ASC, which is composed of a PYD and a CARD, is up-regulated by inflammation and apoptosis in human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

A pilot study of IL-1 inhibition by anakinra in acute gout

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Altered cytokine production in mice lacking P2X(7) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Mechanisms of spreading depression and hypoxic spreading depression-like depolarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

COPs and POPs: modulators of inflammasome activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Preconditioning reprograms the response to ischemic injury and primes the emergence of unique endogenous neuroprotective phenotypes: a speculative synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Functional expression of NOD2, a novel pattern recognition receptor for bacterial motifs, in primary murine astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Toll-like receptors and tolerance to ischaemic injury in the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Signalling pathways and molecular interactions of NOD1 and NOD2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The inflammasome in pathogen recognition and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Major role of HSP70 as a paracrine inducer of cytokine production in human oxidized LDL treated macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Autophagy and inflammatory cell death, partners of innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Fibronectin and laminin increase in the mouse brain after controlled cortical impact injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Cutting edge: ASC mediates the induction of multiple cytokines by Porphyromonas gingivalis via caspase-1-dependent and -independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Identification of CARDIAK, a RIP-like kinase that associates with caspase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

CATERPILLERs, pyrin and hereditary immunological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Neuroprotective role of astrocytes in cerebral ischemia: focus on ischemic preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Activation of complement in the central nervous system: roles in neurodegeneration and neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

PYNOD, a novel Apaf-1/CED4-like protein is an inhibitor of ASC and caspase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Serum urate as an independent predictor of poor outcome and future vascular events after acute stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Fibronectin and neuroprotective effect of granulocyte colony-stimulating factor in focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Nod1, a CARD protein, enhances pro-interleukin-1beta processing through the interaction with pro-caspase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The impact of endogenous triggers on trauma-associated inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Fundamental role of the Rip2/caspase-1 pathway in hypoxia and ischemia-induced neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Exposure to cell phone radiation up-regulates apoptosis genes in primary cultures of neurons and astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

TLR2 has a detrimental role in mouse transient focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Toll-like receptor 2 modulates left ventricular function following ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

High-Mobility Group Box 1 Activates Integrin-Dependent Homing of Endothelial Progenitor Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Role of IL-1alpha and IL-1beta in ischemic brain damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

TLRs, NLRs and RLRs: a trinity of pathogen sensors that co-operate in innate immunity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

The role of the complement cascade in ischemia/reperfusion injury: implications for neuroprotection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

Toll-like receptors 2-deficient mice are protected against postischemic coronary endothelial dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

Regulation of astrocyte proliferation by FGF-2 and heparan sulfate in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

Cutting edge: high-mobility group box 1 preconditioning protects against liver ischemia-reperfusion injury

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

Xanthine and uric acid levels in rat brain following focal ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

Expression of apoptosis-associated speck-like protein containing a caspase recruitment domain, a pyrin N-terminal homology domain-containing protein, in normal human tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

The role of the complement system in traumatic brain injury

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

Expression of interleukin-6, c-fos, and zif268 mRNAs in rat ischemic cortex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

Formation of complement membrane attack complex in mammalian cerebral cortex evokes seizures and neurodegeneration.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

Identifiers

DOI

10.1038/SJ.JCBFM.9600609

1 reference

18 August 2017

1 reference

PubMed ID

18212795