Crosstalk between oxygen- and nitric oxide-dependent signaling pathways in angiogenesis (Q38088893)

28 August 2017

Crosstalk between oxygen- and nitric oxide-dependent signaling pathways in angiogenesis (English)

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28 August 2017

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Peter Fraisl

1

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PubMed ID

23485765

28 August 2017

language of work or name

English

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publication date

26 February 2013

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Experimental Cell Research

28 August 2017

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28 August 2017

319

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28 August 2017

1331-1339

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28 August 2017

9

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Molecular mechanisms and clinical applications of angiogenesis

28 August 2017

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.02.010

Oxygen sensors and angiogenesis

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The biology of VEGF and its receptors

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Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization

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Basic and therapeutic aspects of angiogenesis

7 January 2021

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Angiogenesis: a team effort coordinated by notch.

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Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting

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Regulation of angiogenesis by oxygen and metabolism.

7 January 2021

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Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

7 January 2021

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Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease

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The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer

7 January 2021

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Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1

7 January 2021

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PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage response

7 January 2021

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HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression

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The role of NF-kappaB in hypoxia-induced gene expression.

7 January 2021

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Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1.

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Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

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Mitochondrial reactive oxygen species regulate hypoxic signaling

7 January 2021

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Oxygen-sensing under the influence of nitric oxide

7 January 2021

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Essential role for prolyl hydroxylase domain protein 2 in oxygen homeostasis of the adult vascular system.

7 January 2021

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Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis.

7 January 2021

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Gene-Targeting of Phd2 Improves Tumor Response to Chemotherapy and Prevents Side-Toxicity

7 January 2021

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Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment

7 January 2021

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Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis

7 January 2021

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Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction

7 January 2021

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Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis

7 January 2021

1 reference

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Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

7 January 2021

1 reference

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Disruption of hypoxia-inducible transcription factor-prolyl hydroxylase domain-1 (PHD-1-/-) attenuates ex vivo myocardial ischemia/reperfusion injury through hypoxia-inducible factor-1α transcription factor and its target genes in mice.

7 January 2021

1 reference

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Inhibition of prolyl hydroxylase domain proteins promotes therapeutic revascularization.

7 January 2021

1 reference

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PHD3 regulates differentiation, tumour growth and angiogenesis in pancreatic cancer

7 January 2021

1 reference

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Sprouty2 downregulates angiogenesis during mouse skin wound healing.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.02.010

Regulation of cellular levels of Sprouty2 protein by prolyl hydroxylase domain and von Hippel-Lindau proteins

7 January 2021

1 reference

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The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism

7 January 2021

1 reference

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Double knockdown of prolyl hydroxylase and factor-inhibiting hypoxia-inducible factor with nonviral minicircle gene therapy enhances stem cell mobilization and angiogenesis after myocardial infarction

7 January 2021

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Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

7 January 2021

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Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

7 January 2021

1 reference

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Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha

7 January 2021

1 reference

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Hypoxia-inducible transcription factor-2alpha in endothelial cells regulates tumor neovascularization through activation of ephrin A1

7 January 2021

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HIF-2alpha specifically activates the VE-cadherin promoter independently of hypoxia and in synergy with Ets-1 through two essential ETS-binding sites

7 January 2021

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Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis

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Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis

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Endothelial HIF-2α regulates murine pathological angiogenesis and revascularization processes

7 January 2021

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Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function

7 January 2021

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Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate

7 January 2021

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Nitric oxide as a signal in blood vessels

7 January 2021

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The role of nitric oxide in tumour progression

7 January 2021

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The L-arginine-nitric oxide pathway

7 January 2021

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Nitric oxide synthases: regulation and function

7 January 2021

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Diminished NO release in chronic hypoxic human endothelial cells

7 January 2021

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Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones

7 January 2021

1 reference

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Hypoxia-induced upregulation of eNOS gene expression is redox-sensitive: a comparison between hypoxia and inhibitors of cell metabolism

7 January 2021

1 reference

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Identification of hypoxia-response element in the human endothelial nitric-oxide synthase gene promoter

7 January 2021

1 reference

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Upregulation of eNOS in pregnant ovine uterine arteries by chronic hypoxia

7 January 2021

1 reference

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Decreased endothelial nitric-oxide synthase (eNOS) activity resulting from abnormal interaction between eNOS and its regulatory proteins in hypoxia-induced pulmonary hypertension

7 January 2021

1 reference

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eNOS activation by physical forces: from short-term regulation of contraction to chronic remodeling of cardiovascular tissues.

7 January 2021

1 reference

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Flow-regulated endothelial S1P receptor-1 signaling sustains vascular development

7 January 2021

1 reference

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The sphingosine-1-phosphate receptor S1PR1 restricts sprouting angiogenesis by regulating the interplay between VE-cadherin and VEGFR2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.02.010

Sphingosine-1-phosphate: a novel nonhypoxic activator of hypoxia-inducible factor-1 in vascular cells

7 January 2021

1 reference

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Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis

7 January 2021

1 reference

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Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability

7 January 2021

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The control of vascular integrity by endothelial cell junctions: molecular basis and pathological implications

7 January 2021

1 reference

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S-nitrosylation of beta-catenin by eNOS-derived NO promotes VEGF-induced endothelial cell permeability

7 January 2021

1 reference

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Studies on the reaction of nitric oxide with the hypoxia-inducible factor prolyl hydroxylase domain 2 (EGLN1)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.02.010

Regulation of HIF-1alpha stability through S-nitrosylation

7 January 2021

1 reference

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S-nitrosothiols signal hypoxia-mimetic vascular pathology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.02.010

Endogenous S-nitrosothiols protect against myocardial injury

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.02.010

Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.02.010

Nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.02.010

The interplay between macrophages and angiogenesis in development, tissue injury and regeneration

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.02.010

Monocyte and macrophage heterogeneity

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.02.010

Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.02.010

Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation

7 January 2021

1 reference

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Hypoxia-inducible factor-2α regulates GM-CSF-derived soluble vascular endothelial growth factor receptor 1 production from macrophages and inhibits tumor growth and angiogenesis

7 January 2021

1 reference

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Opposing roles for HIF-1α and HIF-2α in the regulation of angiogenesis by mononuclear phagocytes

7 January 2021

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Stabilization of HIF-2α induces sVEGFR-1 production from tumor-associated macrophages and decreases tumor growth in a murine melanoma model

7 January 2021

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Endothelial cell HIF-1α and HIF-2α differentially regulate metastatic success

7 January 2021

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Hypoxia inducible factor-2alpha in cancer.

7 January 2021

1 reference

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Mitochondria as signaling organelles in the vascular endothelium

7 January 2021

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Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase

7 January 2021

1 reference

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Nitric oxide, cytochrome C oxidase, and the cellular response to hypoxia.

7 January 2021

1 reference

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Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.02.010

Regulation of hypoxia-inducible factor-1alpha by nitric oxide through mitochondria-dependent and -independent pathways.

7 January 2021

1 reference

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Redox signaling in vascular angiogenesis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.02.010

NADPH oxidases as regulators of tumor angiogenesis: current and emerging concepts

7 January 2021

1 reference

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NADPH oxidase 4 promotes endothelial angiogenesis through endothelial nitric oxide synthase activation

7 January 2021

1 reference

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10.1016/J.YEXCR.2013.02.010

7 January 2021

Identifiers

DOI

1 reference

28 August 2017

1 reference

PubMed ID

23485765