Apoptosis regulators and their role in tumorigenesis (Q34395580)

1 August 2017

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title

Apoptosis regulators and their role in tumorigenesis (English)

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1 August 2017

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M Zörnig

1

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1 August 2017

A Hueber

series ordinal

2

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1 August 2017

W Baum

series ordinal

3

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1 August 2017

G Evan

series ordinal

4

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1 August 2017

language of work or name

English

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publication date

1 October 2001

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Biochimica et Biophysica Acta

1 August 2017

published in

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1 August 2017

volume

1551

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1 August 2017

issue

2

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1 August 2017

page(s)

F1-37

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A chronology of cell death

1 August 2017

cites work

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T cell turnover in HIV-1 disease

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Synergistic anti-apoptotic activity between Bcl-2 and SMN implicated in spinal muscular atrophy

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7 January 2021

Cell death mediators in autoimmune diabetes--no shortage of suspects

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7 January 2021

The biochemistry of programmed cell death

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7 January 2021

Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

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7 January 2021

Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.

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7 January 2021

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

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7 January 2021

Phagocyte recognition of cells undergoing apoptosis

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7 January 2021

Recognition and phagocytosis of cells undergoing apoptosis

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7 January 2021

Induction of autophagy and inhibition of tumorigenesis by beclin 1

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7 January 2021

An evolutionary perspective on apoptosis.

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7 January 2021

The origin of programmed cell death

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7 January 2021

Programmed cell death in bacterial populations

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7 January 2021

Genetics of programmed cell death in C. elegans: past, present and future.

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7 January 2021

Genetic control of programmed cell death in the nematode C. elegans.

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7 January 2021

Caenorhabditis elegans gene ced-9 protects cells from programmed cell death

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7 January 2021

CED-4--the third horseman of apoptosis

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7 January 2021

Human ICE/CED-3 protease nomenclature

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7 January 2021

Direct physical interaction between the Caenorhabditis elegans 'death proteins' CED-3 and CED-4.

1 reference

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7 January 2021

Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death

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7 January 2021

CED-4 induces chromatin condensation in Schizosaccharomyces pombe and is inhibited by direct physical association with CED-9.

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7 January 2021

Interaction between the C. elegans cell-death regulators CED-9 and CED-4.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Interaction and regulation of subcellular localization of CED-4 by CED-9

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Role of CED-4 in the activation of CED-3.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Caspases: the executioners of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2

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https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Caenorhabditis elegans CED-9 protein is a bifunctional cell-death inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Human CED-6 encodes a functional homologue of the Caenorhabditis elegans engulfment protein CED-6

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The human homologue of Caenorhabditis elegans CED-6 specifically promotes phagocytosis of apoptotic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: a (p20/p10)2 homodimer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Structure and mechanism of interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Caspase-9 and APAF-1 form an active holoenzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Caspase-9 can be activated without proteolytic processing

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

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7 January 2021

The CARD domain: a new apoptotic signalling motif

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7 January 2021

Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Differential requirement for caspase 9 in apoptotic pathways in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Defects in regulation of apoptosis in caspase-2-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

1 reference

7 January 2021

Caspase structure, proteolytic substrates, and function during apoptotic cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Conversion of Bcl-2 to a Bax-like death effector by caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Modulation of cell death by Bcl-XL through caspase interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Dismantling cell-cell contacts during apoptosis is coupled to a caspase-dependent proteolytic cleavage of beta-catenin.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Cleavage of focal adhesion kinase by caspases during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Caspase-8 is required for cell death induced by expanded polyglutamine repeats.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The baculovirus anti-apoptotic p35 protein promotes transformation of mouse embryo fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Interdigital cell death can occur through a necrotic and caspase-independent pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Apoptosis without caspases: an inefficient molecular guillotine?

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Cytochrome c: can't live with it--can't live without it.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Cytochrome c release from mitochondria: all or nothing

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Mitochondrial control of cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Apoptotic pathways: paper wraps stone blunts scissors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Sequence as well as functional similarity for DIABLO/Smac and Grim, Reaper and Hid?

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Molecular characterization of mitochondrial apoptosis-inducing factor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Identification and functional characterization of DR6, a novel death domain-containing TNF receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Cell death induction by TNF: a matter of self control

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

A naturally occurring soluble isoform of murine Fas generated by alternative splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Fas-ligand: privilege and peril

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The death domain motif found in Fas (Apo-1) and TNF receptor is present in proteins involved in apoptosis and axonal guidance.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Two CD95 (APO-1/Fas) signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Differential modulation of apoptosis sensitivity in CD95 type I and type II cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Daxx, a novel Fas-binding protein that activates JNK and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Sequestration and inhibition of Daxx-mediated transcriptional repression by PML

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Loss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse development

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits fas-mediated Jun NH(2)-terminal kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Inhibition of death receptor signals by cellular FLIP

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

CASH, a novel caspase homologue with death effector domains

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Casper is a FADD- and caspase-related inducer of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The role of c-FLIP in modulation of CD95-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Autoimmunity as a consequence of retrovirus-mediated expression of C-FLIP in lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The inhibitor of death receptor signaling, FLICE-inhibitory protein defines a new class of tumor progression factors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Immune escape of tumors in vivo by expression of cellular FLICE-inhibitory protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Overexpression of M68/DcR3 in human gastrointestinal tract tumors independent of gene amplification and its location in a four-gene cluster

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO-1)-transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

p53-dependent impairment of T-cell proliferation in FADD dominant-negative transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

A role for FADD in T cell activation and development

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Tumor necrosis factor receptor-associated factor (TRAF) family: adapter proteins that mediate cytokine signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

TRAF-interacting protein (TRIP): a novel component of the tumor necrosis factor receptor (TNFR)- and CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Activation of the B-cell surface receptor CD40 induces A20, a novel zinc finger protein that inhibits apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

TRAF family proteins interact with the common neurotrophin receptor and modulate apoptosis induction

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The iap genes: unique arbitrators of cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Caenorhabditis elegans inhibitor of apoptosis protein (IAP) homologue BIR-1 plays a conserved role in cytokinesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Control of apoptosis and mitotic spindle checkpoint by survivin

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Pleiotropic cell-division defects and apoptosis induced by interference with survivin function

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Regulated commitment of TNF receptor signaling: a molecular switch for death or activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

How TRAIL kills cancer cells, but not normal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Death receptors: signaling and modulation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Temperature-sensitive differential affinity of TRAIL for its receptors. DR5 is the highest affinity receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Monocyte-mediated tumoricidal activity via the tumor necrosis factor-related cytokine, TRAIL.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAIL

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Steering anti-cancer drugs away from the TRAIL

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Oncogenes and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Induction of apoptosis in fibroblasts by c-myc protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Regulation of apoptosis by the transforming genes of the DNA tumor virus adenovirus

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Induction of apoptosis by the transcription factor c-Jun

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Induction of apoptosis by c-Fos protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The many roles of c-Myc in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Programmed cell death by default in embryonic cells, fibroblasts, and cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Traps to catch unwary oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

E2F-1 functions in mice to promote apoptosis and suppress proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Inhibition of proliferation and apoptosis by the transcriptional repressor Mad1. Repression of Fas-induced caspase-8 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

1 reference

7 January 2021

Cell cycle: on target with Myc.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

E1A signaling to p53 involves the p19(ARF) tumor suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Role of the p53-homologue p73 in E2F1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Role for the p53 homologue p73 in E2F-1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Induction of apoptosis and differentiation in neuroblastoma and astrocytoma cells by the overexpression of Bin1, a novel Myc interacting protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

c-Myc and E1A induced cellular sensitivity to activated NK cells involves cytotoxic granules as death effectors.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Action of Myc in vivo - proliferation and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Cooperative interaction between c-myc and bcl-2 proto-oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Apoptotic cell death induced by c-myc is inhibited by bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Myc-mediated apoptosis is blocked by ectopic expression of Bcl-2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The Bcl-2 protein family: arbiters of cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bcl-2-family proteins: the role of the BH3 domain in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Erythropoietin can induce the expression of bcl-x(L) through Stat5 in erythropoietin-dependent progenitor cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bcl-XL and Bcl-2 repress a common pathway of cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bcl-XL displays restricted distribution during T cell development and inhibits multiple forms of apoptosis but not clonal deletion in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The proto-oncogene Bcl-2 and its role in regulating apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bax-independent inhibition of apoptosis by Bcl-XL.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bcl-2 counters apoptosis by Bax heterodimerization-dependent and -independent mechanisms in the T-cell lineage

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Heterodimerization-independent functions of cell death regulatory proteins Bax and Bcl-2 in yeast and mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bak can accelerate chemotherapy-induced cell death independently of its heterodimerization with Bcl-XL and Bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

T cells from baxalpha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bax directly induces release of cytochrome c from isolated mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

A novel form of Epstein-Barr virus latency in normal B cells in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The activity of the murine Bax promoter is regulated by Sp1/3 and E-box binding proteins but not by p53

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bax involvement in p53-mediated neuronal cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

BAX is required for neuronal death after trophic factor deprivation and during development

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bcl-2 family proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

A Bad kinase makes good

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Phosphorylation of the pro-apoptotic protein BAD on serine 155, a novel site, contributes to cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Growth factors inactivate the cell death promoter BAD by phosphorylation of its BH3 domain on Ser155.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bcl-2 targets the protein kinase Raf-1 to mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

BID: a novel BH3 domain-only death agonist

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Programmed cell death and Bcl-2 protection in very low oxygen.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The protooncogene bcl-2 inhibits apoptosis in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

bcl-2 inhibits death of central neural cells induced by multiple agents

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

NH2-terminal BH4 domain of Bcl-2 is functional for heterodimerization with Bax and inhibition of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bcl-xL does not inhibit the function of Apaf-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

BCL-2 family members and the mitochondria in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Double identity for proteins of the Bcl-2 family

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Interaction and regulation of the Caenorhabditis elegans death protease CED-3 by CED-4 and CED-9.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Movement of Bax from the cytosol to mitochondria during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Regulation of cell division cycle progression by bcl-2 expression: a potential mechanism for inhibition of programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Regulation of apoptosis and cell cycle progression by MCL1. Differential role of proliferating cell nuclear antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

A link between cell cycle and cell death: Bax and Bcl-2 modulate Cdk2 activation during thymocyte apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bax alpha perturbs T cell development and affects cell cycle entry of T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Apoptosis and the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Apoptosis and the cell cycle: the p53 connection

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Twenty years of p53 research: structural and functional aspects of the p53 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

On the TRAIL from p53 to apoptosis?

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Ultraviolet radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1).

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Involvement of p53 and interleukin 3 in the up-regulation of CD95 (APO-1/Fas) by X-ray irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The c-fos proto-oncogene is a target for transactivation by the p53 tumor suppressor.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

MCG10, a novel p53 target gene that encodes a KH domain RNA-binding protein, is capable of inducing apoptosis and cell cycle arrest in G(2)-M

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Mediation of c-Myc-induced apoptosis by p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

C-myc-induced apoptosis in polycystic kidney disease is Bcl-2 and p53 independent

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Regulation of p53 in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Enhanced phosphorylation of p53 by ATM in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Deacetylation of p53 modulates its effect on cell growth and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Escaping cell death: survival proteins in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The rise and fall of apoptosis during multistage tumorigenesis: down-modulation contributes to tumor progression from angiogenic progenitors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Release from apoptosis correlates with tumor progression in the AKR lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The functional basis of c-myc and bcl-2 complementation during multistep lymphomagenesis in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Bcl-2 accelerates multistep prostate carcinogenesis in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Loss of anti-mitotic effects of Bcl-2 with retention of anti-apoptotic activity during tumor progression in a mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

STAT5-Dependent CyclinD1 and Bcl-xL expression in Bcr-Abl-transformed cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Haploid loss of bax leads to accelerated mammary tumor development in C3(1)/SV40-TAg transgenic mice: reduction in protective apoptotic response at the preneoplastic stage

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Role of BAX in the apoptotic response to anticancer agents

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2 ratio and loss of spontaneous caspase-3 processing in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Somatic mutations in the death domain of the Fas (Apo-1/CD95) gene in gastric cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Mice defective in two apoptosis pathways in the myeloid lineage develop acute myeloblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Inhibition of death receptor signaling by FLICE-inhibitory protein as a mechanism for immune escape of tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Amplification and expression of a decoy receptor for fas ligand (DcR3) in virus (EBV or HTLV-I) associated lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

SADS: A new component of Fas-DISC is the accelerator for cell death signaling and is downregulated in patients with colon carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

RETRACTED: A SADS defect in tumor cells provides optimism.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Tumor cells fight back to beat immune system

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Cutting Edge: The Tumor Counterattack Hypothesis Revisited: Colon Cancer Cells Do Not Induce T Cell Apoptosis Via the Fas (CD95, APO-1) Pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Caspase 8: the killer you can't live without.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Caspase activation is required for T cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The inhibitors of apoptosis (IAPs) and their emerging role in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

High expression of Survivin, mapped to 17q25, is significantly associated with poor prognostic factors and promotes cell survival in human neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Identification of XAF1 as an antagonist of XIAP anti-Caspase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Expression and genetic analysis of XIAP-associated factor 1 (XAF1) in cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

The p53-deficient mouse: a model for basic and applied cancer studies

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

MDM2 induces hyperplasia and premalignant lesions when expressed in the basal layer of the epidermis.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Tumor suppressors. Teaming up to restrain cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Tumorigenic and Developmental Effects of Combined Germ-line Mutations in Rb and p53

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Death and methylation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Apoptosis and APC in colorectal tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Role of promyelocytic leukemia (PML) protein in tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Heat-shock proteins as death determinants

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Induction of apoptosis of metastatic mammary carcinoma cells in vivo by disruption of tumor cell surface CD44 function

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Does cancer therapy trigger cell suicide?

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

From bench to clinic with apoptosis-based therapeutic agents

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Apoptosis and cancer: strategies for integrating programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2801%2900031-2

7 January 2021

10.1016/S0304-419X(01)00031-2

Identifiers

DOI

1 reference

1 August 2017

1 reference