Autophagy, apoptosis, mitoptosis and necrosis: interdependence between those pathways and effects on cancer (Q38066407)

28 August 2017

1 reference

title

Autophagy, apoptosis, mitoptosis and necrosis: interdependence between those pathways and effects on cancer (English)

1 reference

28 August 2017

0 references

1 reference

7

Marek J Los

1 reference

28 August 2017

4

Roman Jaksik

1 reference

28 August 2017

Wiem Chaabane

1

1 reference

28 August 2017

Sırma D User

2

1 reference

28 August 2017

Mohamed El-Gazzah

3

1 reference

28 August 2017

Elaheh Sajjadi

5

1 reference

28 August 2017

Joanna Rzeszowska-Wolny

6

1 reference

28 August 2017

11 December 2012

1 reference

Archivum Immunologiae et Therapiae Experimentalis

28 August 2017

1 reference

28 August 2017

61

1 reference

28 August 2017

43-58

1 reference

28 August 2017

1

1 reference

https://scigraph.springernature.com/pub.10.1007/s00005-012-0205-y

28 August 2017

0 references

cites work

Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Tissue transglutaminase inhibits autophagy in pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Virus-triggered autophagy in viral hepatitis - possible novel strategies for drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

The roles of therapy-induced autophagy and necrosis in cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

The ubiquitin pathway: an emerging drug target in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

AT-101 induces apoptosis in CLL B cells and overcomes stromal cell-mediated Mcl-1 induction and drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Serum cytochrome c indicates in vivo apoptosis and can serve as a prognostic marker during cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

ATP steal between cation pumps: a mechanism linking Na+ influx to the onset of necrotic Ca2+ overload.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

PUMA couples the nuclear and cytoplasmic proapoptotic function of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

A RNA interference screen identifies RIP3 as an essential inducer of TNF-induced programmed necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Direct cleavage by the calcium-activated protease calpain can lead to inactivation of caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Thymocyte apoptosis induced by p53-dependent and independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Identification of RIP1 kinase as a specific cellular target of necrostatins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Detection of a transformation-related antigen in chemically induced sarcomas and other transformed cells of the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Death receptor-induced apoptotic and necrotic cell death: differential role of caspases and mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Apoptosis: a review of programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Targeted therapy against Bcl-2-related proteins in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Autophagy is induced by ischemic preconditioning in human livers formerly treated by chemotherapy to limit necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

The coordinate regulation of the p53 and mTOR pathways in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Apoptosis and cancer: mutations within caspase genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

An efficient approach for the isolation, identification and evaluation of antimicrobial plant components on an analytical scale, demonstrated by the example of Radix imperatoriae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Ablation of key oncogenic pathways by RITA-reactivated p53 is required for efficient apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Obesity: pathophysiology and clinical management

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Nutlin-3 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through up-regulation of death receptor 5 (DR5) in human sarcoma HOS cells and human colon cancer HCT116 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Mitoptosis, a novel mitochondrial death mechanism leading predominantly to activation of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

mu-Calpain mediated cleavage of the Na+/Ca2+ exchanger in isolated mitochondria under A23187 induced Ca2+ stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Is mPTP the gatekeeper for necrosis, apoptosis, or both?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Mechanisms of antileukemic activity of the novel Bcl-2 homology domain-3 mimetic GX15-070 (obatoclax).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Prognostic significance of apoptosis regulators in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

T antigen is bound to a host protein in SY40-transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Caspase-dependent and -independent pathways for cadmium-induced apoptosis in cultured kidney proximal tubule cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Four deaths and a funeral: from caspases to alternative mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

A small molecule inhibitor of inducible heat shock protein 70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

New, exciting developments in experimental therapies in the early 21st century.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Caspases: more than just killers?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Anticancer drugs of tomorrow: apoptotic pathways as targets for drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Switching Akt: from survival signaling to deadly response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Apoptin, a tumor-selective killer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

p53 is required for radiation-induced apoptosis in mouse thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Novel mechanism of elimination of malfunctioning mitochondria (mitoptosis): formation of mitoptotic bodies and extrusion of mitochondrial material from the cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Cell survival, cell death and cell cycle pathways are interconnected: implications for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Akt-mediated phosphorylation of CDK2 regulates its dual role in cell cycle progression and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Unscheduled Akt-triggered activation of cyclin-dependent kinase 2 as a key effector mechanism of apoptin's anticancer toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Stimulation of autophagy by the p53 target gene Sestrin2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

z-VAD-fmk-induced non-apoptotic cell death of macrophages: possibilities and limitations for atherosclerotic plaque stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Anti-tumour cytotoxin produced by human monocytes: studies on its mode of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Autophagy in health and disease. 1. Regulation and significance of autophagy: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Autophagy: regulation and role in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

p53 has a direct apoptogenic role at the mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Mitophagy and mitoptosis in disease processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Autophagy: renovation of cells and tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

p53 and Nur77/TR3 - transcription factors that directly target mitochondria for cell death induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Bcl-2-targeted antisense therapy (Oblimersen sodium): towards clinical reality

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Apaf-1 is a transcriptional target for E2F and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Modeling of molecular interaction between apoptin, BCR-Abl and CrkL--an alternative approach to conventional rational drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Targeting Bcl-2 family members with the BH3 mimetic AT-101 markedly enhances the therapeutic effects of chemotherapeutic agents in in vitro and in vivo models of B-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Necrosis: a specific form of programmed cell death?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Novel Insights into the Interplay between Apoptosis and Autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Oblimersen combined with docetaxel, adriamycin and cyclophosphamide as neo-adjuvant systemic treatment in primary breast cancer: final results of a multicentric phase I study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Changes in poly(ADP-ribose) level modulate the kinetics of DNA strand break rejoining

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Toxic proteins released from mitochondria in cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Sestrin2 modulates AMPK subunit expression and its response to ionizing radiation in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

BID regulation by p53 contributes to chemosensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Bcl-xES, a BH4- and BH2-containing antiapoptotic protein, delays Bax oligomer formation and binds Apaf-1, blocking procaspase-9 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

The morphology of various types of cell death in prenatal tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

The MDM-2 antagonist nutlin-3 promotes the maturation of acute myeloid leukemic blasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Bioenergetic aspects of apoptosis, necrosis and mitoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Necroptosis, necrostatins and tissue injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Anticancer effects of the p53 activator nutlin-3 in Ewing's sarcoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Regulation of autophagy by cytoplasmic p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

p53 represses autophagy in a cell cycle-dependent fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Apoptosis and autophagy: regulatory connections between two supposedly different processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

WT p53, but not tumor-derived mutants, bind to Bcl2 via the DNA binding domain and induce mitochondrial permeabilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Calpain-induced Bax-cleavage product is a more potent inducer of apoptotic cell death than wild-type Bax.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Preclinical studies of the pan-Bcl inhibitor obatoclax (GX015-070) in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Tumor necrosis factor-mediated cell death: to break or to burst, that's the question

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Caspase inhibitors promote alternative cell death pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

The role of the kinases RIP1 and RIP3 in TNF-induced necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

The complex interplay between autophagy, apoptosis, and necrotic signals promotes T-cell homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

RETRACTED ARTICLE. Localized synovial hypertrophy in the anteromedial compartment of the osteoarthritic knee

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Implications of genomic instability in the diagnosis and treatment of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

The effect of genetic variability on drug response in conventional breast cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Silencing of elongation factor-2 kinase potentiates the effect of 2-deoxy-D-glucose against human glioma cells through blunting of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Cell death: the significance of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Regulation of p53 responses by post-translational modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

The N-terminal domain of tumor suppressor p53 is involved in the molecular interaction with the anti-apoptotic protein Bcl-Xl.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

Whole-body physiologically based pharmacokinetic model for nutlin-3a in mice after intravenous and oral administration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

High-Resolution Melting Analysis for Mutation Screening of RGSL1, RGS16, and RGS8 in Breast Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00005-012-0205-Y

10.1007/S00005-012-0205-Y

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

28 August 2017

0 references

1 reference