Autophagy: regulation and role in disease (Q37529825)

20 August 2017

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title

Autophagy: regulation and role in disease (English)

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20 August 2017

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2

Patrice Codogno

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20 August 2017

Alfred J Meijer

1

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20 August 2017

1 January 2009

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Critical Reviews in Clinical Laboratory Sciences

20 August 2017

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20 August 2017

46

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20 August 2017

210-240

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20 August 2017

4

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Ubiquitin-mediated proteolysis: biological regulation via destruction

20 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy and the ubiquitin-proteasome system: collaborators in neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy and aging: keeping that old broom working

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy: from phenomenology to molecular understanding in less than a decade

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy in the Pathogenesis of Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy fights disease through cellular self-digestion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Protein turnover via autophagy: implications for metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy and other vacuolar protein degradation mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Microtubules support production of starvation-induced autophagosomes but not their targeting and fusion with lysosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The itinerary of autophagosomes: from peripheral formation to kiss-and-run fusion with lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy: a lysosomal degradation pathway with a central role in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy: molecular machinery for self-eating

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Molecular machinery of autophagosome formation in yeast, Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Hierarchy of Atg proteins in pre-autophagosomal structure organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

New insights into the mechanisms of macroautophagy in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The cell biology of autophagy in metazoans: a developing story

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Molecular dissection of autophagy: two ubiquitin-like systems

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408360903044068

The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

How to interpret LC3 immunoblotting

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

LC3, an autophagosome marker, can be incorporated into protein aggregates independent of autophagy: caution in the interpretation of LC3 localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy-independent incorporation of GFP-LC3 into protein aggregates is dependent on its interaction with p62/SQSTM1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy: a forty-year search for a missing membrane source

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Endoplasmic reticulum and autophagy in rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy and related mechanisms of lysosome-mediated protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Role and regulation of starvation-induced autophagy in the Drosophila fat body

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Growth factor regulation of autophagy and cell survival in the absence of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Inhibition of macroautophagy triggers apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The role of autophagy during the early neonatal starvation period

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagic proteolysis: control and specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Influence of glucagon, an inducer of cellular autophagy, on some physical properties of rat liver lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Loss of autophagy in the central nervous system causes neurodegeneration in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy and signaling: their role in cell survival and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Amino acids interfere with the ERK1/2-dependent control of macroautophagy by controlling the activation of Raf-1 in human colon cancer HT-29 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

A novel cell type-specific role of p38α in the control of autophagy and cell death in colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Mitochondrially localized ERK2 regulates mitophagy and autophagic cell stress: implications for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The hepatocyte integrin system and cell volume sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Erk1/2-dependent phosphorylation of Galpha-interacting protein stimulates its GTPase accelerating activity and autophagy in human colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

An obligatory requirement for the heterotrimeric G protein Gi3 in the antiautophagic action of insulin in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

TOR signaling in growth and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The amino acid sensitive TOR pathway from yeast to mammals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Insulin and amino-acid regulation of mTOR signaling and kinase activity through the Rheb GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Stress and mTORture signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Bridging the GAP between insulin signaling and GLUT4 translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Molecular mechanisms through which amino acids mediate signaling through the mammalian target of rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Amino acid regulation of TOR complex 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Amino acid regulation of autophagosome formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Muscarinic receptor-mediated activation of p70 S6 kinase 1 (S6K1) in 1321N1 astrocytoma cells: permissive role of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

In yeast, loss of Hog1 leads to osmosensitivity of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy genes are essential for dauer development and life-span extension in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Trypanosome TOR as a major regulator of cell growth and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy in the control of programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Plant autophagy--more than a starvation response

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Small molecule enhancers of autophagy for neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Methods for monitoring autophagy from yeast to human

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Aberrant insulin receptor signaling and amino acid homeostasis as a major cause of oxidative stress in aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Tor-mediated induction of autophagy via an Apg1 protein kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Organization of the pre-autophagosomal structure responsible for autophagosome formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Tap42-associated protein phosphatase type 2A negatively regulates induction of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Bcl-2 family members: dual regulators of apoptosis and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Class III phosphoinositide 3-kinase--Beclin1 complex mediates the amino acid-dependent regulation of autophagy in C2C12 myotubes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The autophagic response to nutrient deprivation in the hl-1 cardiac myocyte is modulated by Bcl-2 and sarco/endoplasmic reticulum calcium stores

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Hepatic amino acid-dependent signaling is under the control of AMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMP-activated protein kinase and protein phosphatases in isolated hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Naringin-sensitive phosphorylation of plectin, a cytoskeletal cross-linking protein, in isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

A possible linkage between AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

AMP-activated Protein Kinase and the Regulation of Autophagic Proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Beyond AICA riboside: in search of new specific AMP-activated protein kinase activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Role of AMP-activated protein kinase in autophagy and proteasome function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The role of autophagy in mediating cell survival and death during ischemia and reperfusion in the heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

A critical role of eEF-2K in mediating autophagy in response to multiple cellular stresses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Elongation factor-2 kinase regulates autophagy in human glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

AMPK phosphorylation of raptor mediates a metabolic checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The role of AMPK and mTOR in nutrient sensing in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Leucine-enriched nutrients and the regulation of mammalian target of rapamycin signalling and human skeletal muscle protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

S6 kinase deletion suppresses muscle growth adaptations to nutrient availability by activating AMP kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Dietary energy restriction modulates the activity of AMP-activated protein kinase, Akt, and mammalian target of rapamycin in mammary carcinomas, mammary gland, and liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Role of dietary proteins and amino acids in the pathogenesis of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy and p70S6 kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

ATG1, an autophagy regulator, inhibits cell growth by negatively regulating S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Sch9 is a major target of TORC1 in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Protein kinase A and Sch9 cooperatively regulate induction of autophagy in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

FoxO3 controls autophagy in skeletal muscle in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Gene expression profiling identifies FKBP39 as an inhibitor of autophagy in larval Drosophila fat body.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

mTOR regulates autophagy-associated genes downstream of p73.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Stressing the role of FoxO proteins in lifespan and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Cell growth control: mTOR takes on fat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Potential role of leucine metabolism in the leucine-signaling pathway involving mTOR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Structural requirement of leucine for activation of p70 S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Amino Acids and Insulin Control Autophagic Proteolysis through Different Signaling Pathways in Relation to mTOR in Isolated Rat Hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Exogenous amino acids regulate trophectoderm differentiation in the mouse blastocyst through an mTOR-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a target of rapamycin-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Amino acid transceptors: gate keepers of nutrient exchange and regulators of nutrient signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Bidirectional transport of amino acids regulates mTOR and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Signalling pathways and combinatory effects of insulin and amino acids in isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Amino acid signaling through the mammalian target of rapamycin (mTOR) pathway: Role of glutamine and of cell shrinkage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Metabolic regulation by leucine of translation initiation through the mTOR-signaling pathway by pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Re-evaluating the roles of proposed modulators of mammalian target of rapamycin complex 1 (mTORC1) signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Translational regulation of GCN4 and the general amino acid control of yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Phosphatidic acid-mediated mitogenic activation of mTOR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

mTOR signaling: PLD takes center stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Phospholipase D1 is an effector of Rheb in the mTOR pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

hvps34, an ancient player, enters a growing game: mTOR Complex1/S6K1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

hVps15, but not Ca2+/CaM, is required for the activity and regulation of hVps34 in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Transport of phosphatidylinositol 3-phosphate into the vacuole via autophagic membranes in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Regulation of glycogen synthesis by amino acids in cultured human muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Rheb binding to mammalian target of rapamycin (mTOR) is regulated by amino acid sufficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Regulation of the small GTPase Rheb by amino acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Regulation of TORC1 by Rag GTPases in nutrient response

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

FKBP12-Rapamycin-associated Protein or Mammalian Target of Rapamycin (FRAP/mTOR) Localization in the Endoplasmic Reticulum and the Golgi Apparatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Constitutively active Rheb induces oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Nutrient sensing: TOR's Ragtime

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

L-leucine and a nonmetabolized analogue activate pancreatic islet glutamate dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Control of proteolysis in perifused rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

How mitochondria produce reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The role of mitochondria in reactive oxygen species metabolism and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The tricarboxylic acid cycle, an ancient metabolic network with a novel twist

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Lipid oxidation and autophagy in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

NF-kappaB activation represses tumor necrosis factor-alpha-induced autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

ROS, mitochondria and the regulation of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Regulation of autophagy by reactive oxygen species (ROS): implications for cancer progression and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The regulation of AMP-activated protein kinase by H(2)O(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Metabolic cycling in control of glucose-stimulated insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Principles of bioactive lipid signalling: lessons from sphingolipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Ceramide starves cells to death by downregulating nutrient transporter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Ceramide-induced formation of ROS and ATP depletion trigger necrosis in lymphoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Tumor necrosis factor (TNF)-alpha inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Induction of autophagic cell death and radiosensitization by the pharmacological inhibition of nuclear factor-kappa B activation in human glioma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Nuclear factor-kappaB in cancer development and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy and NF-kappaB: fight for fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Regulation of autophagy by sphingosine kinase 1 and its role in cell survival during nutrient starvation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Nonselective autophagy of cytosolic enzymes by isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Degradation and turnover of peroxisomes in the yeast Hansenula polymorpha induced by selective inactivation of peroxisomal enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Pexophagy: the selective autophagy of peroxisomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy in organelle homeostasis: peroxisome turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy: principles and significance in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagic degradation of peroxisomes in isolated rat hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Excess peroxisomes are degraded by autophagic machinery in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Turnover of glycosomes during life-cycle differentiation of Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The peroxin Pex14p is involved in LC3-dependent degradation of mammalian peroxisomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

PpAtg30 tags peroxisomes for turnover by selective autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Uth1p is involved in the autophagic degradation of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Aup1p, a yeast mitochondrial protein phosphatase homolog, is required for efficient stationary phase mitophagy and cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Mitophagy in yeast occurs through a selective mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Selective degradation of mitochondria by mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Different fates of mitochondria: alternative ways for degradation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Coenzyme Q deficiency triggers mitochondria degradation by mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

NIX is required for programmed mitochondrial clearance during reticulocyte maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Essential role for Nix in autophagic maturation of erythroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Regulation of mitochondrial integrity, autophagy and cell survival by BNIP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Hypoxia signalling through mTOR and the unfolded protein response in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Mitochondrial autophagy: life and breath of the cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Prolyl hydroxylases as regulators of cell metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Parkin mitochondria in the autophagosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Rethinking the mitochondrial theory of aging: the role of mitochondrial gene expression in lifespan determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Impaired autophagy: A mechanism of mitochondrial dysfunction in anoxic rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The interplay between pro-death and pro-survival signaling pathways in myocardial ischemia/reperfusion injury: apoptosis meets autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy is activated for cell survival after endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Endoplasmic reticulum stress triggers autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Eating the endoplasmic reticulum: quality control by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Endoplasmic reticulum and Golgi complex: Contributions to, and turnover by, autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The role of autophagy in alpha-1-antitrypsin deficiency: a specific cellular response in genetic diseases associated with aggregation-prone proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Glycogen autophagy in glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Self-eating and self-killing: crosstalk between autophagy and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy in aging, disease and death: the true identity of a cell death impostor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The selectivity of autophagy and its role in cell death and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Does autophagy have a license to kill mammalian cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy and cell death in model organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagic cell death: the story of a misnomer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagic cell death unraveled: Pharmacological inhibition of apoptosis and autophagy enables necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Nutrient deprivation induces autophagy as well as apoptosis in Chinese hamster ovary cell culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Glutamine increases autophagy under Basal and stressed conditions in intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy plays a protective role during zVAD-induced necrotic cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagic programmed cell death by selective catalase degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Crosstalk between Bak/Bax and mTOR signaling regulates radiation-induced autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Dual roles of autophagy in the survival of Caenorhabditis elegans during starvation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Oxidative damage and mitochondrial decay in aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy and aging: the importance of maintaining "clean" cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Extension of murine life span by overexpression of catalase targeted to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy and neurodegeneration: when the cleaning crew goes on strike

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

How to live long and prosper: autophagy, mitochondria, and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The role of autophagy in aging: its essential part in the anti-aging mechanism of caloric restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Mitochondrial turnover in liver is fast in vivo and is accelerated by dietary restriction: application of a simple dynamic model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The endocrine regulation of aging by insulin-like signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The role of insulin and IGF-1 signaling in longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Endocrine regulation of ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Insulin/IGF-1 and ROS signaling pathway cross-talk in aging and longevity determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy genes and ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Mitochondrial dysfunction and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Ubiquitinated-protein aggregates form in pancreatic beta-cells during diabetes-induced oxidative stress and are regulated by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Protective role of autophagy in palmitate-induced INS-1 beta-cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The insulin resistance syndrome: definition and dietary approaches to treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The insulin paradox: aging, proteotoxicity and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy: a sweet process in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Mitochondrial dysfunction in the elderly: possible role in insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Suppression of aging in mice by the hormone Klotho

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Functionally significant insulin-like growth factor I receptor mutations in centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

FOXO3A genotype is strongly associated with human longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Sirtuins as potential targets for metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Comparing and contrasting the roles of AMPK and SIRT1 in metabolic tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Mitochondria--a nexus for aging, calorie restriction, and sirtuins?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Regulation of autophagy by the p300 acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

FoxO transcription factors in the maintenance of cellular homeostasis during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Resveratrol in cell fate decisions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Resveratrol-induced autophagocytosis in ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Non-canonical autophagy: an exception or an underestimated form of autophagy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Resveratrol is a class IA phosphoinositide 3-kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Anticancer action of cubé insecticide: correlation for rotenoid constituents between inhibition of NADH:ubiquinone oxidoreductase and induced ornithine decarboxylase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Characterization of NAD uptake in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Cholesterol depletion induces autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Selective inhibition of growth of tuberous sclerosis complex 2 null cells by atorvastatin is associated with impaired Rheb and Rho GTPase function and reduced mTOR/S6 kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Hydrophobic statins induce autophagy in cultured human rhabdomyosarcoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy in hypoxia-ischemia induced brain injury: evidence and speculations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Statin modulates insulin signaling and insulin resistance in liver and muscle of rats fed a high-fat diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Effect of rosuvastatin on insulin sensitivity in an animal model of insulin resistance: evidence for statin-induced hepatic insulin sensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy, amyloidogenesis and Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The roles of intracellular protein-degradation pathways in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Rapamycin inhibits polyglutamine aggregation independently of autophagy by reducing protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy: for better or for worse, in good times or in bad times

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Enhancing macroautophagy protects against ischemia/reperfusion injury in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The role of autophagy in the heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Molecular mechanisms and physiological significance of autophagy during myocardial ischemia and reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Recycle or die: the role of autophagy in cardioprotection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

PI3K pathway alterations in cancer: variations on a theme

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

mTOR Complex1-S6K1 signaling: at the crossroads of obesity, diabetes and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Defining the role of mTOR in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy signaling and the cogwheels of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Tumor suppression by autophagy through the management of metabolic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy and cancer: dynamism of the metabolism of tumor cells and tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy: an emerging target for cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Control of autophagy by oncogenes and tumor suppressor genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The paradox of autophagy and its implication in cancer etiology and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The coordinate regulation of the p53 and mTOR pathways in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Regulation of autophagy by cytoplasmic p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

p53: The Janus of autophagy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Macroautophagy inhibition sensitizes tamoxifen-resistant breast cancer cells and enhances mitochondrial depolarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Induction of autophagy and inhibition of tumorigenesis by beclin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Hypoxia signalling in cancer and approaches to enforce tumour regression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy-physiology and pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

A block of autophagy in lysosomal storage disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy is disrupted in a knock-in mouse model of juvenile neuronal ceroid lipofuscinosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Oxidative stress and autophagy in the regulation of lysosome-dependent neuron death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy in Niemann-Pick C disease is dependent upon Beclin-1 and responsive to lipid trafficking defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Pathogenetic mechanisms of hepatic encephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Identifying the direct effects of ammonia on the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Signaling factors in the mechanism of ammonia neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Loss of tuberous sclerosis complex 1 (Tsc1) expression results in increased Rheb/S6K pathway signaling important for astrocyte cell size regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Unveiling the roles of autophagy in innate and adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Enhancing immunity through autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Human immunodeficiency virus type-1 infection inhibits autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

The Atg5 Atg12 conjugate associates with innate antiviral immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

Induction of autophagy by amino-acid deprivation in perfused rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360903044068

10.1080/10408360903044068

21 January 2018

Identifiers

DOI

1 reference

20 August 2017

1 reference

PubMed ID

19552522