Signaling Cross Talk between TGF-β/Smad and Other Signaling Pathways (Q39005862)

8 September 2017

1 reference

title

Signaling Cross Talk between TGF-β/Smad and Other Signaling Pathways (English)

1 reference

8 September 2017

Kunxin Luo

1

1 reference

8 September 2017

11 November 2016

1 reference

Cold Spring Harbor Perspectives in Biology

8 September 2017

1 reference

8 September 2017

9

1 reference

8 September 2017

1

1 reference

Ubiquitin-mediated activation of TAK1 and IKK.

8 September 2017

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

A Smad action turnover switch operated by WW domain readers of a phosphoserine code

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Phosphatidylinositol 3-kinase is involved in alpha2(I) collagen gene expression in normal and scleroderma fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TGFbeta and Wnt pathway cross-talk

21 January 2018

2 references

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

21 January 2018

12 December 2020

Smads as transcriptional co-modulators

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Switch enhancers interpret TGF-β and Hippo signaling to control cell fate in human embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Induction of Olig2 precursors by FGF involves BMP signalling blockade at the Smad level

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

PIKKing on PKB: regulation of PKB activity by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

IKK(α) controls canonical TGF(ß)-SMAD signaling to regulate genes expressing SNAIL and SLUG during EMT in panc1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Efficient TGF-beta induction of the Smad7 gene requires cooperation between AP-1, Sp1, and Smad proteins on the mouse Smad7 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TRAF6 is a signal transducer for interleukin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Integration of external signaling pathways with the core transcriptional network in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Smad signaling antagonizes STAT5-mediated gene transcription and mammary epithelial cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Akt interacts directly with Smad3 to regulate the sensitivity to TGF-beta induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Cooperation between the activin and Wnt pathways in the spatial control of organizer gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Synergistic effects of Vg1 and Wnt signals in the specification of dorsal mesoderm and endoderm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Carcinogen-induced pancreatic lesions in the mouse: effect of Smad4 and Apc genotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Nodal signaling recruits the histone demethylase Jmjd3 to counteract polycomb-mediated repression at target genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Regulation of Notch signaling genes during BMP2-induced differentiation of osteoblast precursor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Cloning of the human GLI2 Promoter: transcriptional activation by transforming growth factor-beta via SMAD3/beta-catenin cooperation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

IKKalpha is a critical coregulator of a Smad4-independent TGFbeta-Smad2/3 signaling pathway that controls keratinocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Elucidation of a universal size-control mechanism in Drosophila and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

HER2/Neu- and TAK1-mediated up-regulation of the transforming growth factor beta inhibitor Smad7 via the ETS protein ER81

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

PI 3-kinase, Akt and cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Role of YAP/TAZ in mechanotransduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Granulosa cell-expressed BMPR1A and BMPR1B have unique functions in regulating fertility but act redundantly to suppress ovarian tumor development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Mad is required for wingless signaling in wing development and segment patterning in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Phosphorylation of Mad controls competition between wingless and BMP signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

APC and Smad7 link TGFβ type I receptors to the microtubule system to promote cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

SMADs and YAP compete to control elongation of β-catenin:LEF-1-recruited RNAPII during hESC differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Smurf1-mediated Lys29-linked nonproteolytic polyubiquitination of axin negatively regulates Wnt/β-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Specificity and versatility in tgf-beta signaling through Smads

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-beta/Smad signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TGF-β and NF-κB signal pathway cross-talk is mediated through TAK1 and SMAD7 in a subset of head and neck cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TGF-β synergizes with defects in the Hippo pathway to stimulate human malignant mesothelioma growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Requirement of BMP-2-induced phosphatidylinositol 3-kinase and Akt serine/threonine kinase in osteoblast differentiation and Smad-dependent BMP-2 gene transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TGF-beta coordinately activates TAK1/MEK/AKT/NFkB and SMAD pathways to promote osteoclast survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TRAF6 stimulates the tumor-promoting effects of TGFβ type I receptor through polyubiquitination and activation of presenilin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Signaling cross-talk between TGF-beta/BMP and other pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Tumor suppressor LATS1 is a negative regulator of oncogene YAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Mechanism of TGF-beta signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

The TGFβ1 pathway is required for NFκB dependent gene expression in mouse keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Noncanonical TGFβ signaling contributes to aortic aneurysm progression in Marfan syndrome mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

BMP-2/-4 and Wnt-8 cooperatively pattern the Xenopus mesoderm

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor-beta1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an autocrine growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

A signalling relay involving Nodal and Delta ligands acts during secondary notochord induction in Ciona embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Sequential and combinatorial inputs from Nodal, Delta2/Notch and FGF/MEK/ERK signalling pathways establish a grid-like organisation of distinct cell identities in the ascidian neural plate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Gli proteins in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Smad4 and β-Catenin Co-activators Functionally Interact with Lymphoid-enhancing Factor to Regulate Graded Expression of Msx2

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TGF-beta induces p65 acetylation to enhance bacteria-induced NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

SnoN regulates mammary gland alveologenesis and onset of lactation by promoting prolactin/Stat5 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Crosstalk between TGF-β and hedgehog signaling in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TGF-beta1 enhances betaig-h3-mediated keratinocyte cell migration through the alpha3beta1 integrin and PI3K.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Smad3-dependent nuclear translocation of beta-catenin is required for TGF-beta1-induced proliferation of bone marrow-derived adult human mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

The protein stability of Axin, a negative regulator of Wnt signaling, is regulated by Smad ubiquitination regulatory factor 2 (Smurf2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Chromatin and transcriptional signatures for Nodal signaling during endoderm formation in hESCs

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

IκB kinase γ/nuclear factor-κB-essential modulator (IKKγ/NEMO) facilitates RhoA GTPase activation, which, in turn, activates Rho-associated KINASE (ROCK) to phosphorylate IKKβ in response to transforming growth factor (TGF)-β1

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Vertebrate mesendoderm induction and patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Autophagy is activated by TGF-beta and potentiates TGF-beta-mediated growth inhibition in human hepatocellular carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Cooperation between SMAD and NF-kappaB in growth factor regulated type VII collagen gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Wnt signaling in adult intestinal stem cells and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Default neural induction: neuralization of dissociated Xenopus cells is mediated by Ras/MAPK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Cell size and invasion in TGF-beta-induced epithelial to mesenchymal transition is regulated by activation of the mTOR pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TGF-β-induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

The TAK1-TRAF6 signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

ALK1 signaling inhibits angiogenesis by cooperating with the Notch pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

The type II transforming growth factor-beta receptor autophosphorylates not only on serine and threonine but also on tyrosine residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TGF-beta1 modulates matrix metalloproteinase-13 expression in hepatic stellate cells by complex mechanisms involving p38MAPK, PI3-kinase, AKT, and p70S6k.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Integrin-linked kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

The murine gastrin promoter is synergistically activated by transforming growth factor-beta/Smad and Wnt signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Canonical and non-canonical JAK-STAT signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

BMP4 Signaling Acts via dual-specificity phosphatase 9 to control ERK activity in mouse embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Ubiquitination and proteolysis of cancer-derived Smad4 mutants by SCFSkp2

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Smads bind directly to the Jun family of AP-1 transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TACE-mediated ectodomain shedding of the type I TGF-beta receptor downregulates TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF{beta}-TrCP E3 ligase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Transforming growth factor-β (TGF-β)-mediated connective tissue growth factor (CTGF) expression in hepatic stellate cells requires Stat3 signaling activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

A genetic regulatory network for Xenopus mesendoderm formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Phosphatidylinositol 3 kinase/Akt signal relay cooperates with smad in bone morphogenetic protein-2-induced colony stimulating factor-1 (CSF-1) expression and osteoclast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TAK1 lysine 158 is required for TGF-β-induced TRAF6-mediated Smad-independent IKK/NF-κB and JNK/AP-1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TGFβ signalling in context

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Notch1 oncoprotein antagonizes TGF-beta/Smad-mediated cell growth suppression via sequestration of coactivator p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Identification and characterization of ERK MAP kinase phosphorylation sites in Smad3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Integration of Hedgehog and BMP signalling by the engrailed2a gene in the zebrafish myotome

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

A negative feedback control of transforming growth factor-beta signaling by glycogen synthase kinase 3-mediated Smad3 linker phosphorylation at Ser-204.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TGF-beta-RI kinase inhibitor SD-208 reduces the development and progression of melanoma bone metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

A Failure of Transforming Growth Factor-β1 Negative Regulation Maintains Sustained NF-κB Activation in Gut Inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Non-Smad signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Master transcription factors determine cell-type-specific responses to TGF-β signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Cell density sensing alters TGF-β signaling in a cell-type-specific manner, independent from Hippo pathway activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Notch signaling is necessary for epithelial growth arrest by TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Wnt, activin, and BMP signaling regulate distinct stages in the developmental pathway from embryonic stem cells to blood.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Cutaneous Notch signaling in health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

The transcription factor GLI1 interacts with SMAD proteins to modulate transforming growth factor β-induced gene expression in a p300/CREB-binding protein-associated factor (PCAF)-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Suppression of matrix metalloproteinase-9 transcription by transforming growth factor-beta is mediated by a nuclear factor-kappaB site

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Cooperative regulation of growth by Yorkie and Mad through bantam

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Regulation of the Hippo pathway and implications for anticancer drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Overlapping activities of TGF-β and Hedgehog signaling in cancer: therapeutic targets for cancer treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

The biology of YAP/TAZ: hippo signaling and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

The Sno oncogene antagonizes Wingless signaling during wing development in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Wg signaling via Zw3 and mad restricts self-renewal of sensory organ precursor cells in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

The intracellular form of notch blocks transforming growth factor beta-mediated growth arrest in Mv1Lu epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Ski regulates Hippo and TAZ signaling to suppress breast cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

PKB/Akt modulates TGF-beta signalling through a direct interaction with Smad3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Bmp2 antagonizes sonic hedgehog-mediated proliferation of cerebellar granule neurones through Smad5 signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

SMAD3 expression is regulated by mitogen-activated protein kinase kinase-1 in epithelial and smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

The Phosphatidylinositol 3-Kinase/Akt Pathway Enhances Smad3-stimulated Mesangial Cell Collagen I Expression in Response to Transforming Growth Factor-β1

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Oncogenic ras represses transforming growth factor-beta /Smad signaling by degrading tumor suppressor Smad4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

New insights into extracellular and post-translational regulation of TGF-β family signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Signaling network crosstalk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

A discrete period of FGF-induced Erk1/2 signalling is required for vertebrate neural specification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Smoothened antagonists reverse taxane resistance in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Notch4 intracellular domain binding to Smad3 and inhibition of the TGF-beta signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Combinatorial gene regulation by Bmp and Wnt in zebrafish posterior mesoderm formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Smad-dependent GADD45beta expression mediates delayed activation of p38 MAP kinase by TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Enhanced gene activation by Notch and BMP signaling cross-talk

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Pluripotency factors regulate definitive endoderm specification through eomesodermin

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Involvement of MAP kinase cascades in Smad7 transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Transforming growth factor beta1 (TGF-beta1) promotes endothelial cell survival during in vitro angiogenesis via an autocrine mechanism implicating TGF-alpha signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Casein kinase Iepsilon plays a functional role in the transforming growth factor-beta signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Transforming growth factor-{beta}-inducible phosphorylation of Smad3

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

YAP, TAZ, and Yorkie: a conserved family of signal-responsive transcriptional coregulators in animal development and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

STAT3 selectively interacts with Smad3 to antagonize TGF-β

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Direct activation of protein kinases by unanchored polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

MicroRNA-216a/217-induced epithelial-mesenchymal transition targets PTEN and SMAD7 to promote drug resistance and recurrence of liver cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Ectodermal Smad4 and p38 MAPK are functionally redundant in mediating TGF-beta/BMP signaling during tooth and palate development

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TGF-beta1 increases motility and alphavbeta3 integrin up-regulation via PI3K, Akt and NF-kappaB-dependent pathway in human chondrosarcoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Involvement of Ras in extraembryonic endoderm differentiation of embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

The Hippo pathway: regulators and regulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

FGF2 sustains NANOG and switches the outcome of BMP4-induced human embryonic stem cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Coordinated activation of notch, Wnt, and transforming growth factor-beta signaling pathways in bone morphogenic protein 2-induced osteogenesis. Notch target gene Hey1 inhibits mineralization and Runx2 transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TEAD mediates YAP-dependent gene induction and growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Notch and TGFβ form a positive regulatory loop and regulate EMT in epithelial ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

TGF-beta1 inhibits caspase-3 activation and neuronal apoptosis in rat hippocampal cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Neuroprotection by transforming growth factor-beta1 involves activation of nuclear factor-kappaB through phosphatidylinositol-3-OH kinase/Akt and mitogen-activated protein kinase-extracellular-signal regulated kinase1,2 signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

mTOR: from growth signal integration to cancer, diabetes and ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Anterior endomesoderm specification in Xenopus by Wnt/beta-catenin and TGF-beta signalling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A022137

Downregulation of interleukin-12 (IL-12) responsiveness in human T cells by transforming growth factor-beta: relationship with IL-12 signaling

21 January 2018

1 reference

12 December 2020

A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA

1 reference

12 December 2020

Structure, function, and biology of SHIP proteins

1 reference

12 December 2020

Interaction and functional cooperation of NF-kappa B with Smads. Transcriptional regulation of the junB promoter

1 reference

12 December 2020

Beta-catenin, MAPK and Smad signaling during early Xenopus development.

1 reference

12 December 2020

Stimulation of osteoblastic cell differentiation by Notch

1 reference

12 December 2020

Wnt and Bmp signalling cooperatively regulate graded Emx2 expression in the dorsal telencephalon.

1 reference

12 December 2020

The roles of three signaling pathways in the formation and function of the Spemann Organizer.

1 reference

12 December 2020

No effects of Smad2 (madh2) null mutation on malignant progression of intestinal polyps in Apc(delta716) knockout mice.

1 reference

12 December 2020

Compound disruption of smad2 accelerates malignant progression of intestinal tumors in apc knockout mice

1 reference

12 December 2020

Transient activation of NF-kappaB through a TAK1/IKK kinase pathway by TGF-beta1 inhibits AP-1/SMAD signaling and apoptosis: implications in liver tumor formation

1 reference

12 December 2020

Transforming growth factor-beta activation of phosphatidylinositol 3-kinase is independent of Smad2 and Smad3 and regulates fibroblast responses via p21-activated kinase-2

1 reference

12 December 2020

BMP-2-enhanced chondrogenesis involves p38 MAPK-mediated down-regulation of Wnt-7a pathway

1 reference

12 December 2020

Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker

1 reference

12 December 2020

Src phosphorylates Tyr284 in TGF-beta type II receptor and regulates TGF-beta stimulation of p38 MAPK during breast cancer cell proliferation and invasion

1 reference

12 December 2020

Role of Smads in TGFβ signaling

1 reference

12 December 2020

TGF-β/SMAD/GLI2 signaling axis in cancer progression and metastasis

1 reference

12 December 2020

USP4 is regulated by AKT phosphorylation and directly deubiquitylates TGF-β type I receptor

1 reference

12 December 2020

Smad6 inhibits non-canonical TGF-β1 signalling by recruiting the deubiquitinase A20 to TRAF6.

1 reference

12 December 2020

The IκB kinase complex in NF-κB regulation and beyond

1 reference

12 December 2020

SnoN Antagonizes the Hippo Kinase Complex to Promote TAZ Signaling during Breast Carcinogenesis

1 reference

12 December 2020

TGF-beta inhibits IL-12-induced activation of Jak-STAT pathway in T lymphocytes

1 reference

12 December 2020

10.1101/CSHPERSPECT.A022137

Identifiers

DOI

1 reference

8 September 2017

0 references

1 reference

PubMed ID

27836834