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main subject
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published in
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DOI
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Association of sperm protein 17 with A-kinase anchoring protein 3 in flagella
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reproductive medicine Sperm autoantigenic protein 17 A-kinase anchoring protein 3 Sperm autoantigenic protein 17
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Reproductive Biology and Endocrinology
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10.1186/1477-7827-2-57
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8
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In vitro antibacterial activity of some plant essential oils
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Thymus vulgaris Cinnamon Origanum vulgare Cinnamomum zeylanicum p-cymene alpha-terpineol oct-1-en-3-ol (+/-)-linalool carvacrol myrcene eugenol (E)-cinnamaldehyde thymol α-terpinene γ‑terpinene caryophyllene essential oil
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BMC Complementary and Alternative Medicine
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10.1186/1472-6882-6-39
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19
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RBT1, a novel transcriptional co-activator, binds the second subunit of replication protein A
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SERTA domain containing 3 Replication protein A2 regulation of transcription, DNA-templated
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Nucleic Acids Research
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10.1093/NAR/28.18.3478
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11
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CABYR, a novel calcium-binding tyrosine phosphorylation-regulated fibrous sheath protein involved in capacitation
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phosphorylation sperm capacitation Calcium binding tyrosine phosphorylation regulated
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Developmental Biology
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10.1006/DBIO.2001.0527
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6
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Relationships between the sequence of alpha-synuclein and its membrane affinity, fibrillization propensity, and yeast toxicity
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fibrillization Synuclein gamma Synuclein beta Synuclein alpha Synuclein, alpha Synuclein
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Journal of Molecular Biology
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10.1016/J.JMB.2006.12.044
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7
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The unfolded protein response induces the angiogenic switch in human tumor cells through the PERK/ATF4 pathway
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Activating transcription factor 4 Eukaryotic translation initiation factor 2 alpha kinase 3 positive regulation of transcription by RNA polymerase I Eukaryotic translation initiation factor 2 alpha kinase 3
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Cancer Research
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10.1158/0008-5472.CAN-12-0474
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12
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Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53
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apoptotic process endoplasmic reticulum Transformation related protein 53 BCL2 binding component 3 Apoptotic peptidase activating factor 1 Phorbol-12-myristate-13-acetate-induced protein 1
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Journal of Biological Chemistry
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10.1074/JBC.M509868200
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8
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Endothelin-converting enzyme-1 regulates endosomal sorting of calcitonin receptor-like receptor and beta-arrestins
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cell biology Endothelin converting enzyme 1 Calcitonin receptor like receptor Receptor activity modifying protein 1
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Journal of Cell Biology
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10.1083/JCB.200704053
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11
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Conductin/axin2 and Wnt signalling regulates centrosome cohesion
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Axin 2 catenin beta 1 regulation of centromeric sister chromatid cohesion Axin 2 Catenin (cadherin associated protein), beta 1
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EMBO Reports
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10.1038/EMBOR.2010.23
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13
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IRIP, a new ischemia/reperfusion-inducible protein that participates in the regulation of transporter activity
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cell biology Solute carrier family 6 member 2 Solute carrier family 22 member 3 Solute carrier family 22 member 6 Solute carrier family 22 member 2 Solute carrier family 6 member 3 solute carrier family 6 member 4 organic anion transmembrane transporter activity Solute carrier family 22 (organic cation transporter), member 2 Solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 Solute carrier family 22 (organic cation transporter), member 3 Solute carrier family 22 (organic anion transporter), member 6 Solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 Solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
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Molecular and Cellular Biology
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10.1128/MCB.25.15.6496-6508.2005
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32
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The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding
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homeostatic iron regulator Beta-2-microglobulin Transferrin Transferrin receptor negative regulation of signaling receptor activity ligand binding
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Proceedings of the National Academy of Sciences of the United States of America
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10.1073/PNAS.95.4.1472
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11
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HOP/NECC1, a novel regulator of mouse trophoblast differentiation
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Serum response factor HOP homeobox negative regulation of cell differentiation Serum response factor HOP homeobox
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Journal of Biological Chemistry
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10.1074/JBC.M701380200
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9
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Human colonic epithelial cells detect and respond to C5a via apically expressed C5aR through the ERK pathway
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Complement component 5a receptor 2 Complement C5a receptor 1 regulation of interleukin-8 production
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American Journal of Physiology - Cell Physiology
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10.1152/AJPCELL.00213.2011
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7
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Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes
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SUB1 regulator of transcription regulation of transcription by RNA polymerase II
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Cell
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10.1016/0092-8674(94)90428-6
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6
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ALIX binds a YPX(3)L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sorting
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cell biology G protein-coupled receptor ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway F2R like trypsin receptor 1 Charged multivesicular body protein 4C Charged multivesicular body protein 4B Programmed cell death 6 interacting protein coagulation factor II thrombin receptor Vacuolar protein sorting 4 homolog B Vacuolar protein sorting 4 homolog A
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Journal of Cell Biology
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10.1083/JCB.201110031
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13
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A mammalian homolog of Drosophila tumorous imaginal discs, Tid1, mediates agrin signaling at the neuromuscular junction
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Drosophila Muscle, skeletal, receptor tyrosine kinase DnaJ heat shock protein family (Hsp40) member A3 neuromuscular junction
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Neuron
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10.1016/J.NEURON.2008.09.025
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13
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Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway
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ubiquitin-proteasome system Siah E3 ubiquitin protein ligase 1 axon guidance Seven in absentia Dmel_CG9949
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Genes & Development
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10.1101/GAD.11.20.2701
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10
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The identification of a succinyl-CoA thioesterase suggests a novel pathway for succinate production in peroxisomes
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glutaryl-CoA hydrolase activity Acyl-CoA thioesterase 8 Acyl-CoA thioesterase 4 acyl-CoA hydrolase activity
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Journal of Biological Chemistry
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10.1074/JBC.M508479200
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9
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STT3B-dependent posttranslational N-glycosylation as a surveillance system for secretory protein
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STT3 oligosaccharyltransferase complex catalytic subunit B Derlin 3 Ubiquitin conjugating enzyme E2 J1 Valosin containing protein Synoviolin 1 Ubiquitin conjugating enzyme E2 G2 ubiquitin-dependent ERAD pathway glycosylation
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Molecular Cell
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10.1016/J.MOLCEL.2012.04.015
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24
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A study of the topoisomerase II activity in HIV-1 replication using the ferrocene derivatives as probes
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viral integration complex DNA topoisomerase II beta DNA topoisomerase II alpha positive regulation of single stranded viral RNA replication via double stranded DNA intermediate
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Archives of Biochemistry and Biophysics
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10.1016/J.ABB.2006.04.003
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6
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The HARP-like domain-containing protein AH2/ZRANB3 binds to PCNA and participates in cellular response to replication stress
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cell biology ATP-dependent DNA/DNA annealing activity DNA rewinding SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 Zinc finger RANBP2-type containing 3 RAD54 like SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
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Molecular Cell
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10.1016/J.MOLCEL.2012.05.025
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19
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Isolation and characterization of a transcriptional cofactor and its novel isoform that bind the deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma
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Helicase with zinc finger 2 Peroxisome proliferator activated receptor gamma positive regulation of transcription by RNA polymerase II Peroxisome proliferator activated receptor gamma
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Endocrinology
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10.1210/EN.2005-0450
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18
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Adipolin/C1qdc2/CTRP12 protein functions as an adipokine that improves glucose metabolism
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cell biology glucose C1q and tumor necrosis factor related 12
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Journal of Biological Chemistry
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10.1074/JBC.M111.277319
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9
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How are the sizes of cells, organs, and bodies controlled?
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Hedgehog Dmel_CG4637 Salvador Dmel_CG33193
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PLOS Biology
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10.1371/JOURNAL.PBIO.0000086
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Creative Commons Attribution 4.0 International
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6
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Gamma-linolenic and stearidonic acids are required for basal immunity in Caenorhabditis elegans through their effects on p38 MAP kinase activity
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Caenorhabditis elegans Delta(9)-fatty-acid desaturase fat-6 CELE_VZK822L.1 Galectin CELE_F38A5.3 Dietary restriction down regulated CELE_F49F1.1 Delta(6)-fatty-acid desaturase fat-3;FA_desaturase domain-containing protein CELE_W08D2.4 Delta(12) fatty acid desaturase fat-2 CELE_W02A2.1 CUB_2 domain-containing protein CELE_F08G5.6 Saposin B-type domain-containing protein CELE_T07C4.4 Lysozyme-like protein 2 CELE_Y22F5A.5 Lysozyme-like protein 7 CELE_C02A12.4
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PLOS Genetics
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10.1371/JOURNAL.PGEN.1000273
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Creative Commons Attribution 4.0 International
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10
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Spa2p functions as a scaffold-like protein to recruit the Mpk1p MAP kinase module to sites of polarized growth
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Spa2p YLL021W Mitogen-activated protein kinase kinase MKK1 YOR231W Putative mitogen-activated protein kinase kinase MKK2 YPL140C Mitogen-activated serine/threonine-protein kinase SLT2 YHR030C
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Current Biology
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10.1016/S0960-9822(02)01186-7
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20
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Members of the evolutionarily conserved PMT family of protein O-mannosyltransferases form distinct protein complexes among themselves
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dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt2p dimer complex dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt3p dimer complex dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p homodimer complex dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt3p dimer complex dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex Dolichyl-phosphate-mannose-protein mannosyltransferase PMT1 YDL095W Dolichyl-phosphate-mannose-protein mannosyltransferase PMT2 YAL023C Dolichyl-phosphate-mannose-protein mannosyltransferase YJR143C Putative dolichyl-phosphate-mannose-protein mannosyltransferase PMT5 YDL093W Dolichyl-phosphate-mannose-protein mannosyltransferase PMT3 YOR321W
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Journal of Biological Chemistry
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10.1074/JBC.M212582200
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16
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Overproduction and affinity purification of Saccharomyces cerevisiae replication factor C.
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Saccharomyces cerevisiae Replication factor C subunit 1 YOR217W Replication factor C subunit 2 YJR068W Replication factor C subunit 4 YOL094C Replication factor C subunit 3 YNL290W Replication factor C subunit 5 YBR087W
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Journal of Biological Chemistry
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10.1074/JBC.272.2.1256
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9
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Attachment of the ubiquitin-related protein Urm1p to the antioxidant protein Ahp1p
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Uba4p YHR111W Ubiquitin-related modifier URM1 YIL008W
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Eukaryotic Cell
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10.1128/EC.2.5.930-936.2003
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7
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The Saccharomyces cerevisiae MADS-box transcription factor Rlm1 is a target for the Mpk1 mitogen-activated protein kinase pathway
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Saccharomyces cerevisiae Rlm1p YPL089C Smp1p YBR182C
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Molecular and Cellular Biology
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10.1128/MCB.17.4.1848
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6
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Variable region sequences of five human immunoglobulin heavy chains of the VH3 subgroup: definitive identification of four heavy chain hypervariable regions
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Ig heavy chain V-III region JON Ig heavy chain V-III region 23 immune response
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Proceedings of the National Academy of Sciences of the United States of America
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10.1073/PNAS.71.3.845
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9
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Ablation of a Ca2+-activated K+ channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation
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atrial fibrillation Potassium calcium-activated channel subfamily N member 2 membrane repolarization during atrial cardiac muscle cell action potential Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
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Journal of Physiology
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10.1113/JPHYSIOL.2008.167718
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10
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Plocamium hamatum and its monoterpenes: chemical and biological investigations of the tropical marine red alga
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Plocamium hamatum 2beta-Bromo-4beta-chloro-1alpha-[(E)-2-chloroethenyl]-5-methylene-1-methylcyclohexane (2S,5S,6R)-1,5-Dibromo-2,6-dichloro-2,6-dimethyl-3,7-octadiene (3S,4S,5E,7S)-4,8-dibromo-3,7-dichloro-3,7-dimethyl-octa-1,5-diene (1S,2S,4R,5R)-2-Bromo-1-bromomethyl-1,4-dichloro-5-((E)-2-chloro-vinyl)-5-methyl-cyclohexane Mertensene Aplysiaterpenoid A (4S,6S)-4,6-Dibromo-1-chloro-7-methylene-3-methyl-2-octene (1S,2S,4S)-2,4-dichloro-1-[(E)-2-chlorovinyl]-1-methyl-5-methylene-cyclohexane 4beta-Bromo-2beta-chloro-1beta-[(E)-2-chloroethenyl]-5-methylene-1-methylcyclohexane (1R,2R,4S,5R)-4-bromo-1,2-dichloro-5-[(E)-2-chlorovinyl]-1,5-dimethyl-cyclohexane (2S,5S,6S,7S)-1,5,7-Tribromo-2,6,8-trichloro-2,6-dimethyl-3-octene
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Phytochemistry
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10.1016/S0031-9422(99)00284-8
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11
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Phenolic compounds from the leaves of Cornus controversa
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Cornus controversa Gemin D eugeniin gallic acid kaempferol-3-O-alpha-L-rhamnoside hyperoside quercetin quercitrin rutin 5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3S,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one afzelin Kaempferol-3-O-rhamnoside Cornus kousa
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Phytochemistry
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10.1016/S0031-9422(99)00502-6
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11
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Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice
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apoptotic process BCL2-like 1 B cell leukemia/lymphoma 2 BCL2-associated X protein BCL2-antagonist/killer 1 BCL2-like 2 BH3 interacting domain death agonist BCL2-associated agonist of cell death Lactate dehydrogenase A cytochrome c oxidase subunit 4I2
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Journal of Cell Biology
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10.1083/JCB.200110108
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19
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CPEB4 is a cell survival protein retained in the nucleus upon ischemia or endoplasmic reticulum calcium depletion
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endoplasmic reticulum Cytoplasmic polyadenylation element binding protein 1 Cytoplasmic polyadenylation element binding protein 4 Cytoplasmic polyadenylation element binding protein 3
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Molecular and Cellular Biology
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10.1128/MCB.00716-10
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19
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Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis
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cell line apoptotic process Apoptotic peptidase activating factor 1 cytochrome c, somatic
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Cell
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10.1016/S0092-8674(00)80849-1
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6
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The mammalian guanine nucleotide exchange factor mSec12 is essential for activation of the Sar1 GTPase directing endoplasmic reticulum export
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endoplasmic reticulum Prolactin regulatory element binding Secretion associated Ras related GTPase 1B guanine
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Traffic
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10.1034/J.1600-0854.2001.20704.X
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6
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TIF1beta/KAP-1 is a coactivator of the orphan nuclear receptor NGFI-B/Nur77
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Nuclear receptor subfamily 4, group A, member 2 Proline, glutamic acid and leucine rich protein 1 GATA zinc finger domain containing 2B MYB binding protein (P160) 1a Nuclear receptor subfamily 4, group A, member 1 Metastasis-associated gene family, member 2 Tripartite motif-containing 28
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Journal of Biological Chemistry
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10.1074/JBC.M809023200
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13
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Immunolocalization of the mitogen-activated protein kinases p42MAPK and JNK1, and their regulatory kinases MEK1 and MEK4, in adult rat central nervous system
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nervous system
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The Journal of Comparative Neurology
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<373::AID-CNE6>3.0.CO;2-X 10.1002/(SICI)1096-9861(19980831)398:3<373::AID-CNE6>3.0.CO;2-X
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9
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The role of interleukin 1 receptor-associated kinase-4 (IRAK-4) kinase activity in IRAK-4-mediated signaling
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interleukins Interleukin 6 Interleukin-1 receptor-associated kinase 1 Interleukin 1 beta Interleukin-1 receptor-associated kinase 4 Interleukin 1 receptor, type I
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Journal of Biological Chemistry
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10.1074/JBC.M402666200
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15
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Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex
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Lin-7 homolog A, crumbs cell polarity complex component Lin-7 homolog B, crumbs cell polarity complex component Lin-7 homolog C, crumbs cell polarity complex component Calcium/calmodulin-dependent serine protein kinase (MAGUK family) Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 Amyloid beta (A4) precursor protein binding, family A, member 1 neurotransmitter
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Journal of Cell Biology
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10.1083/JCB.200503011
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13
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Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice
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Laminin B1 Laminin subunit gamma-1 Laminin, alpha 2 Laminin, alpha 4 Laminin, beta 2 Laminin, alpha 5
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Journal of Cell Biology
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10.1083/JCB.139.6.1507
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19
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Tipo,minthostachys mollis (lamiaceae): an ecuadorian mint
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Minthostachys mollis (2-isopropyl-5-methylcyclohexyl)acetic acid (-)-limonene (3Z)-β-ocimene beta-pinene (3E)-β-ocimene menthyl acetate (-)-isomenthone sabinene DL-piperitone p-menthan-3-ol (–)-menthone alpha-pinene myrcene p-menthan-3-one humulene (+)-neoisomenthol (+)-neomenthol ethinylestradiol pulegone caryophyllene Lamiaceae isomenthyl acetate (-)-isomenthol Neomenthyl acetate
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Economic Botany
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10.1007/BF02901380
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21
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Antidiabetic principles of natural medicines. IV. Aldose reductase and qlpha-glucosidase inhibitors from the roots of Salacia oblonga Wall. (Celastraceae): structure of a new friedelane-type triterpene, kotalagenin 16-acetate
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Helionides oblonga Salacia oblonga glycerol (2S,4S,4aR,6aS,6bR,8aR,10S,12aR,12bR,14bS)-4,10-dihydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-2-carboxylic acid keto-D-fructose 3beta,22beta-Dihydroxyolean-12-en-29-oic acid raffinose [6a-(hydroxymethyl)-2,2,4a,6a,8a,9,14a-heptamethyl-10,12-dioxo-3,4,5,6,6b,7,8,9,12a,13,14,14b-dodecahydro-1H-picen-5-yl] acetate Stachyose hydrate Kotalagenin 16-acetate galactinol 4'-methyl-epigallocatechin 26-Hydroxy-1,3-friedelanedione hexane-1,2,3,4,5,6-hexol galactitol 1,2,3,4,4a,9,10,10a-Octahydro-6-hydroxy-7-isopropyl-1,4a-dimethyl-1-phenanthrenemethanol 19-Hydroxyferruginol stachyose lambertic acid D-glucopyranose Gal(a1-6)D-Ido(a1-6)Glc(a1-2b)Psif alpha-D-Glucopyranoside, beta-D-fructofuranosyl O-alpha-D-galactopyranosyl-(1.fwdarw.6)- D-fructopyranose 3-O-(6-O-alpha-D-Galactopyranosyl-beta-D-galactopyranosyl)-L-glycerol sucrose Celastraceae [1-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)thiolan-1-ium-1-yl]-2,4,5,6,7-pentahydroxyheptan-3-yl] sulfate Salacinol
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Chemical & Pharmaceutical Bulletin
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10.1248/CPB.47.1725
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|
32
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CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis
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Caspase recruitment domain family member 8 receptor interacting serine/threonine kinase 2 Caspase recruitment domain family member 16 Apoptotic peptidase activating factor 1 Fas associated via death domain B cell CLL/lymphoma 10 CASP2 and RIPK1 domain containing adaptor with death domain Caspase recruitment domain family member 18 Caspase 1 Caspase 9 inhibition of cysteine-type endopeptidase activity apoptotic process
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Journal of Biological Chemistry
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10.1074/JBC.M107811200
|
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31
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Antiproliferative activity against human non-small cell lung cancer of two O-alkyl-diglycosylglycerols from the marine sponges Myrmekioderma dendyi and Trikentrion laeve
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Myrmekioderma dendyi Trikentrion laeve [(2R,3S,4R,5R,6R)-5-acetamido-3,4-dihydroxy-6-[1-(18-hydroxy-9-methyloctadecoxy)-3-[(2R,3R,4S,5R)-3,4,5-triacetyloxyoxan-2-yl]oxypropan-2-yl]oxyoxan-2-yl]methyl acetate (2S,3R,4S,5R)-2-[(2R)-3-tetracos-17-enoxy-2-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxypropoxy]oxane-3,4,5-triol (2S,3R,4S,5R)-2-[(2R)-3-[(Z)-tetracos-17-enoxy]-2-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxypropoxy]oxane-3,4,5-triol N-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-[1-(18-hydroxy-9-methyloctadecoxy)-3-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxypropan-2-yl]oxyoxan-3-yl]acetamide (2S,3R,4S,5R)-2-[2-[(2R,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-(18-hydroxy-9-methyloctadecoxy)propoxy]oxane-3,4,5-triol non-small-cell lung carcinoma 2-[2-[3-Amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-(18-hydroxy-9-methyloctadecoxy)propoxy]oxane-3,4,5-triol [5-Acetamido-3,4-dihydroxy-6-[1-(18-hydroxy-9-methyloctadecoxy)-3-(3,4,5-triacetyloxyoxan-2-yl)oxypropan-2-yl]oxyoxan-2-yl]methyl acetate
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European Journal of Medicinal Chemistry
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10.1016/J.EJMECH.2012.01.029
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14
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New isoflavones and flavanol from Iris potaninii
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Iris potaninii ombuin 3,3',5-Trihydroxy-4',7-dimethoxyflavanone iriskumaonin Iriflogenin Irisflorentin 3',5',8-Trihydroxy-4',7-dimethoxy-6-(beta-D-glucopyranosyloxy)isoflavone Blumeatin B 3',4',6-Trimethoxy-5',7,8-trihydroxyisoflavone irisolone Dichotomitin 2-(4-hydroxybenzoyl)benzene-1,3,5-triol
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Chemical & Pharmaceutical Bulletin
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10.1248/CPB.50.1367
|
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10
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The structure of scytonemin, an ultraviolet sunscreen pigment from the sheaths of cyanobacteria
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Cyanobacteria Scytonemin Scytonema Lyngbya Cyanobacterium (3Z)-3-[(4-hydroxyphenyl)methylidene]-1-[(3Z)-3-[(4-hydroxyphenyl)methylidene]-2-oxocyclopenta[b]indol-1-yl]cyclopenta[b]indol-2-one scytonemin ultraviolet radiation Scytonemin, Lyngbya sp. Stigonema
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Experientia
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10.1007/BF01923559
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8
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Polystachynes A-E, five cis-neo-clerodane diterpenoids from Salvia polystachya
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Salvia lineata Salvia polystachia (1R,2R,10S,12S,14R,16R,18S)-16-(furan-3-yl)-18-methyl-8,13,15-trioxapentacyclo[10.5.1.01,14.02,10.06,10]octadeca-3,5-dien-7-one (1R,2S,3S,5R,7S,11S,13R,15S,17R,19S)-17-(furan-3-yl)-19-methyl-4,9,14,16-tetraoxahexacyclo[11.5.1.01,15.02,11.03,5.07,11]nonadecan-8-one Polystachyne B Polystachyne E (1R,2R,3S,5R,7S,11S,13R,15R,17R,19S)-17-(furan-3-yl)-19-methyl-4,9,14,16-tetraoxahexacyclo[11.5.1.01,15.02,11.03,5.07,11]nonadecan-8-one (1S,4S,7R,9R,10S)-7-(furan-3-yl)-9-methyl-6,16-dioxatetracyclo[8.7.0.01,14.04,9]heptadeca-11,13-diene-5,15-dione (1R,2R,3S,5R,7R,11S,13R,15R,17R,19S)-17-(furan-3-yl)-19-methyl-4,9,14,16-tetraoxahexacyclo[11.5.1.01,15.02,11.03,5.07,11]nonadecan-8-one (1S,4S,7R,9R,10S,11R,13S,15S)-7-(furan-3-yl)-9-methyl-6,12,17-trioxapentacyclo[8.8.0.01,15.04,9.011,13]octadecane-5,16-dione (1S,2R,10S,12R,14R,16R,18S)-16-(furan-3-yl)-18-methyl-8,13,15-trioxapentacyclo[10.5.1.01,14.02,10.06,10]octadeca-3,5-dien-7-one Polystachyne D (1S,4S,7R,9R,10S,11R,13S)-7-(furan-3-yl)-9-methyl-6,12,17-trioxapentacyclo[8.8.0.01,15.04,9.011,13]octadec-14-ene-5,16-dione (1S,4S,6R,8R,9S)-6-(furan-3-yl)-4,8-dimethyl-5,15-dioxatetracyclo[7.7.0.01,13.04,8]hexadec-12-en-14-one (1R,2S,3S,5R,7R,11S,13R,15S,17R,19S)-17-(furan-3-yl)-19-methyl-4,9,14,16-tetraoxahexacyclo[11.5.1.01,15.02,11.03,5.07,11]nonadecan-8-one (1S,4S,7R,9R,10S,11R,13S,15R)-7-(furan-3-yl)-9-methyl-6,12,17-trioxapentacyclo[8.8.0.01,15.04,9.011,13]octadecane-5,16-dione (1S,2R,6S,10S,12R,14S,16R,18S)-16-(furan-3-yl)-18-methyl-8,13,15-trioxapentacyclo[10.5.1.01,14.02,10.06,10]octadec-3-en-7-one Polystachyne C Polystachyne A Salvia xalapensis
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Phytochemistry
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10.1016/S0031-9422(99)00466-5
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24
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New iridoid glucosides from the aerial parts of Verbena brasiliensis
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Verbena brasiliensis AC1O52VJ beta-sitosterol Aralidioside sitogluside (1S)-1alpha-(beta-D-Glucopyranosyloxy)-5beta-hydroxy-1,4aalpha,5,6,7,7aalpha-hexahydrocyclopenta[c]pyran-4,7alpha-dicarboxylic acid dimethyl ester Gelsemiol 3-glucoside (+)-lyoniresinol-3-alpha-O-beta-D-glucopyranoside ZINC05234420 dimethyl (1S,4aS,7S,7aS)-5-oxo-1-[(2S,3S,4S,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4a,6,7,7a-tetrahydro-1H-cyclopenta[c]pyran-4,7-dicarboxylate [[Q105183066|(2R,3R,4S,5S,6S)-2-[[(3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol]] dimethyl (1S,4aS,7S,7aS)-5-oxo-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4a,6,7,7a-tetrahydro-1H-cyclopenta[c]pyran-4,7-dicarboxylate Verbenabraside B dimethyl (1S,4aR,7S,7aR)-4a-hydroxy-5-oxo-1-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,6,7,7a-tetrahydrocyclopenta[c]pyran-4,7-dicarboxylate 9-Hydroxysemperoside verbascoside [[Q105121497|[(2R,3S,4S,5R,6R)-6-[[(3R,3aS,4S,5S,6aS)-4-hydroxy-4-(hydroxymethyl)-5-methyl-2-oxo-3a,5,6,6a-tetrahydro-3H-cyclopenta[b]furan-3-yl]methoxy]-3,4,5-trihydroxyoxan-2-yl]methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate]] Leucosceptoside A Griselinoside [[Q105124183|[(2R,3S,4S,5R,6R)-6-[[(3S,3aS,4R,5S,6aS)-4-(hydroxymethyl)-5-methyl-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-3-yl]methoxy]-3,4,5-trihydroxyoxan-2-yl]methyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate]] Verbenabraside A beta-Sitosterol 3-O-beta-D-galactopyranoside Xyl(b1-2)Gal(b)-O-EtPh (1R,4S,6S,7S,11S)-7-hydroxy-6-methyl-1-[(2S,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,9-dioxatricyclo[5.3.1.04,11]undecan-2-one Phenethyl 2-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside Verbraside 7-Hydroxy-6-methyl-1-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,9-dioxatricyclo[5.3.1.04,11]undecan-2-one Verbena officinalis
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Chemical & Pharmaceutical Bulletin
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10.1248/CPB.54.1421
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26
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The F-box protein MEC-15 (FBXW9) promotes synaptic transmission in GABAergic motor neurons in C. elegans
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Caenorhabditis elegans positive regulation of synaptic vesicle transport negative regulation of synaptic vesicle transport regulation of synaptic vesicle transport Ras-related protein Rab-3 CELE_C18A3.6 Synaptobrevin-1 CELE_T10H9.4 F-box/WD repeat-containing protein mec-15 CELE_T01E8.4 Liprin-alpha CELE_F59F5.6
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PLOS One
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10.1371/JOURNAL.PONE.0059132
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Creative Commons Attribution 4.0 International
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9
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Three new compounds from Aspergillus terreus PT06-2 grown in a high salt medium
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Aspergillus terreus [[Q105250843|(2R)-4-hydroxy-2-[[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]methyl]-3-(4-hydroxyphenyl)-2H-furan-5-one]] Aspernolide A [[Q105003261|methyl (2R)-2-[[3-[[(2R)-3,3-dimethyloxiran-2-yl]methyl]-4-hydroxyphenyl]methyl]-4-hydroxy-3-(4-hydroxyphenyl)-5-oxofuran-2-carboxylate]] Aspernolide B [[Q104991275|2-[[2-[(3-Pyridinylcarbonyl)amino]benzoyl]amino]-3,4,5-trimethoxybenzoic acid methyl ester]] Terremide B (R)-6-hydroxymellein Methyl (2~{r})-3-(4-Hydroxyphenyl)-2-[(4-Hydroxyphenyl)methyl]-4-Oxidanyl-5-Oxidanylidene-Furan-2-Carboxylate Terremide A (2R)-2-[(2,2-dimethyl-3,4-dihydrochromen-6-yl)methyl]-4-hydroxy-3-(4-hydroxyphenyl)-2H-furan-5-one (3R,4S)-4,6,8-trihydroxy-3-methyl-3,4-dihydroisochromen-1-one (1R,12R)-1-methyl-3,13,21,23-tetrazahexacyclo[10.10.2.02,10.04,9.013,22.015,20]tetracosa-2(10),4,6,8,15,17,19,21-octaene-14,24-dione terrein Butyrolactone i territrem b
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Marine Drugs
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10.3390/MD9081368
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Creative Commons Attribution 4.0 International
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15
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The messenger RNA decapping and recapping pathway in Trypanosoma
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Nudix hydrolase 2 RNA decapping enzyme RNA capping enzyme, nuclear RNA 3'-terminal phosphate cyclase, putative Mutt-Nudix-related hydrolase 5, putative NUDIX hydrolase 3, putative RNA capping enzyme, cytoplasmic
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Proceedings of the National Academy of Sciences of the United States of America
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10.1073/PNAS.1424909112
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10
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Drosophila p120catenin plays a supporting role in cell adhesion but is not an essential adherens junction component
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Drosophila Armadillo Dmel_CG11579 Adherens junction protein p120 Dmel_CG17484 Shotgun Dmel_CG3722 cell adhesion
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Journal of Cell Biology
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10.1083/JCB.200211083
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7
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HCP-4, a CENP-C-like protein in Caenorhabditis elegans, is required for resolution of sister centromeres
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Caenorhabditis elegans HoloCentric chromosome binding Protein CELE_T03F1.9 HoloCentric chromosome binding Protein CELE_ZK1055.1
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Journal of Cell Biology
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10.1083/JCB.153.6.1199
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11
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A fatty-acid synthesis mechanism specialized for parasitism
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fatty acid fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative fatty acid elongase, putative
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Nature Reviews Microbiology
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10.1038/NRMICRO1617
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63
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A major tyrosine-phosphorylated protein of Trypanosoma brucei is a nucleolar RNA-binding protein
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Trypanosoma brucei phosphorylation nucleolar RNA-binding protein, putative nucleolar RNA-binding protein (fragment) nucleolar RNA-binding protein, putative nucleolar RNA-binding protein nucleolar RNA-binding protein, putative RNA-binding proteins
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Journal of Biological Chemistry
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10.1074/JBC.271.26.15675
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6
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Cannabinoid ester constituents from high-potency Cannabis sativa
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cannabinoids cannabigerolic acid Cannabis sativa alpha-Cadinyl delta9-Tetrahydrocannabinolate 3-(3,7-Dimethylocta-2,6-dienyl)-2,4-dihydroxy-6-pentylbenzoic acid Cannabinolic acid alpha-Fenchyl delta9-Tetrahydrocannabinolate [(1R,2S,4R)-1,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl] (6aR,10aR)-1-hydroxy-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromene-2-carboxylate 2,4-Dihydroxy-3-[(2E)-3,7-dimethyl-2,6-octadienyl]-6-pentylbenzoic acid 1-methyl-1-[(2R)-4aalpha,8-dimethyl-1,2,3,4,4a,5,6,7-octahydronaphthalene-2alpha-yl]ethyl ester [(1R,2S,4S)-1,3,3-trimethyl-2-bicyclo[2.2.1]heptanyl] (6aR,10aR)-1-hydroxy-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromene-2-carboxylate 2-[(2R,4aR)-4a,8-dimethyl-2,3,4,5,6,7-hexahydro-1H-naphthalen-2-yl]propan-2-yl (6aR,10aR)-1-hydroxy-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromene-2-carboxylate alpha-Cadinyl Cannabigerolate (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromene-1,2-diol 2-[(1S)-4-methylcyclohex-3-en-1-yl]propan-2-yl (6aR,10aR)-1-hydroxy-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromene-2-carboxylate Delta-9-Tetrahydrocannabinolic acid [(1R)-4-methyl-1-propan-2-ylcyclohex-3-en-1-yl] 1-hydroxy-6,6,9-trimethyl-3-pentylbenzo[c]chromene-2-carboxylate [(1R)-4-methyl-1-propan-2-ylcyclohex-3-en-1-yl] (6aR,10aR)-1-hydroxy-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromene-2-carboxylate tetrahydrocannabinol
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Journal of Natural Products
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10.1021/NP070454A
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16
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Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans
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putative set3c deacetylase complex subunit serine/threonine-protein kinase, putative serine/threonine-protein kinase, putative putative fyv10 protein homolog ubiquitin carboxyl-terminal hydrolase cyclin-dependent kinase of PITSLRE subfamily nonhistone chromosomal protein virulence related protein of unknown function serine/threonine-protein kinase ubiquitin-specific protease, putative uv excision repair protein rhp23, putative pathway-specific nitrogen regulator, putative damaged DNA binding protein, putative hypothetical protein Putative Zn2-Cys6 zinc-finger transcription factor nuclear pore complex protein putative transcription factor infection related protein of unknown function protein of unknown function polygalacturonase, putative endoplasmic reticulum protein, putative putative secreted protein ubiquitin-like protein virulence related protein of unknown function GATA family transcription factor Putative Zn2-Cys6 zinc-finger transcription factor urm1 activating enzyme DNA supercoiling, putative LAG1 family transcription factor, putative conserved hypothetical protein histone-lysine N-methyltransferase e3 ubiquitin-protein ligase putative ubiquitin ligase Putative Zn2-Cys6 zinc-finger transcription factor putative transcription factor protein of unknown function glucan 1,3-beta-glucosidase Non-histone chromosomal protein 6, putative hst4 protein, putative putative scaffold protein translin domain protein ubiquitin-conjugating enzyme glycosyl transferase, putative rho GTPase activating protein (GAP) homolog wor1/pac2 family transcription factor putative transcription factor glycosyl hydrolase ubiquitin carboxyl-terminal hydrolase histone deacetylase rtf1 protein, putative rho family GTPase rho family GTPase histone deacetylation-related protein, putative transcriptional activator, putative g1/s-specific cyclin pcl1 (cyclin hcs26), putative specific transcriptional repressor, putative histone-lysine N-methyltransferase, putative similar to cop9 signalosome subunit 4 infection related ring finger protein phosphatidylethanolamine N-methyltransferase, putative ubiquitin-protein ligase, putative UDP-glucose,sterol transferase forkhead transcription factor 3 (freac-3), putative microtubule binding protein, putative specific transcriptional repressor, putative putative histone deacetylase HOS2 DnaJ-like cochaperone e3 ubiquitin-protein ligase pH-response transcription factor pacC/RIM101 expressed protein rab guanyl-nucleotide exchange factor specific RNA polymerase II transcription factor, putative WD40 domain-containing protein Putative zinc finger transcription factor transcription corepressor, putative transcription corepressor, putative similar to cop9 signalosome subunit 7 similar to cop9 signalosome subunit 7 bHLH family transcription factor serine/threonine protein kinase serine/threonine protein kinase eukaryotic translation initiation factor 3 subunit l nuclear distribution protein NudC homolog histone acetyltransferase hypothetical protein virulence related protein of unknown function putative set3c deacetylase complex subunit putative set3c deacetylase complex subunit CAMK/CAMK1/CAMK1-RCK protein kinase macrophage erythroblast attacher isoform 1 ubiquitin carboxyl-terminal hydrolase 1 CMGC/CDK protein kinase cyclin C nonhistone chromosomal protein virulence related protein of unknown function HAL protein kinase ubiquitin carboxyl-terminal hydrolase 8 UV excision repair protein Rad23 pathway-specific nitrogen regulator ATP-dependent DNA helicase 2 subunit 2 hypothetical protein Putative Zn2-Cys6 zinc-finger transcription factor nuclear pore complex protein Nup85 putative transcription factor virulence related protein of unknown function ubiquitin-like protein Nedd8 putative secreted protein endoplasmic reticulum protein similar to Avo2, Tor2 kinase component eukaryotic translation initiation factor 3 subunit l deoxyuridine 5'-triphosphate nucleotidohydrolase putative ubiquitin ligase E3 ubiquitin-protein ligase TRIP12 histone-lysine N-methyltransferase, H3 lysine-4 specific hypothetical protein LAG1 family transcription factor, putative DNA repair and recombination protein RAD54-like protein adenylyltransferase and sulfurtransferase Putative Zn2-Cys6 zinc-finger transcription factor Putative Zn2-Cys6 zinc-finger transcription factor putative transcription factor putative transcription factor hypothetical protein glucan 1,3-beta-glucosidase Non-histone chromosomal protein 6, putative histone deacetylase putative scaffold protein histone deacetylase complex subunit, putative rho family GTPase RNA polymerase-associated protein RTF1 histone deacetylase RPD3 ubiquitin carboxyl-terminal hydrolase 5/13 endoglucanase C putative transcription factor wor1/pac2 family transcription factor wor1/pac2 family transcription factor rho GTPase activating protein (GAP) homolog class E vacuolar protein-sorting machinery protein HSE1 class E vacuolar protein-sorting machinery protein HSE1, variant ubiquitin-conjugating enzyme E2 translin domain protein forkhead transcription factor 3 UDP-glucose,sterol transferase ubiquitin-protein ligase Phosphatidylethanolamine N-methyltransferase BRCA1-associated protein COP9 signalosome complex subunit 4 histone-lysine N-methyltransferase, H3 lysine-36 specific specific transcriptional repressor g1/s-specific cyclin pcl1 compass component spp1 osomolarity two-component system, response regulator SKN7 protein HIR1 COP9 signalosome complex subunit 7 COP9 signalosome complex subunit 7, variant Putative zinc finger transcription factor WD40 domain-containing protein ESCRT-II complex subunit VPS25 bHLH family transcription factor GATA family transcription factor infection related protein of unknown function hypothetical protein COP9 signalosome subunit 12-like protein Polygalacturonase GATA family transcription factor serine/threonine protein kinase CAMK/CAMKL/KIN1 protein kinase nuclear movement protein nudC putative histone acetyltransferase Branched-chain amino acid aminotransferase virulence related protein of unknown function specific RNA polymerase II transcription factor rab guanyl-nucleotide exchange factor virulence related protein of unknown function E3 ubiquitin-protein ligase synoviolin DnaJ-like cochaperone histone deacetylase HOS2 specific transcriptional repressor Cryptococcus neoforman
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Cell
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10.1016/J.CELL.2008.07.046
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68
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Separacenes A-D, novel polyene polyols from the marine actinomycete, Streptomyces sp.
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Streptomyces Streptomyces albidoflavus pentadeca-4,6,8,10,14-pentaene-2,3,12,13-tetrol Separacene B Sungsanpin (3R,4R,5E,7E,9E,11R,12R,13E)-11,12-dimethylpentadeca-1,5,7,9,13-pentaene-3,4-diol Separacene A Separacene D (3R,4S,5E,7E,9E,11R,12R,13E)-11,12-dimethylpentadeca-1,5,7,9,13-pentaene-3,4-diol Separacene C
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Marine Drugs
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10.3390/MD11082882
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Creative Commons Attribution 4.0 International
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8
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Genetic control of specificity to steroid-triggered responses in Drosophila
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Drosophila Lethal (3) persistent salivary gland 2 Dmel_CG5146 BRWD3 Dmel_CG31132 Reptin Dmel_CG9750 Mediator complex subunit 24 Dmel_CG7999 Headcase Dmel_CG15532 Ecdysone receptor Dmel_CG1765 Ecdysone-induced protein 74EF Dmel_CG32180 Broad Dmel_CG11491 Malate dehydrogenase 2 Dmel_CG7998 Belle Dmel_CG9748 Kohtalo Dmel_CG8491
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Genetics
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10.1534/GENETICS.113.159707
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14
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Cinnamrutinoses A and B, glycosides of Populus tremula
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Populus tremula beta-sitosterol salireposide rhamnetin 3,4',5-Trihydroxy-7-methoxyflavanone D-(−)-salicin Liovil (2E)-3-phenyl-2-propen-1-yl-6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside (R)-naringenin [[Q105384148|[(2R,3S,4R,5R,6R)-4,5-dihydroxy-6-[(E)-3-phenylprop-2-enoxy]-2-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-3-yl] benzoate]] tremuloidin pyrocatechol scopoletin [2-[(2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]methyl 1-hydroxy-6-oxocyclohex-2-ene-1-carboxylate salicortin eriodictyol Tremulacin rhamnocitrin naringenin
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Phytochemistry
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10.1016/S0031-9422(00)94801-5
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18
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Bioactivity-guided isolation of anti-inflammatory triterpenoids from the sclerotia of Poria cocos using LPS-stimulated Raw264.7 cells
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poricoic acid A Poria cocos trametenolic acid polyporenic acid c Dehydropachymic acid protocatechualdehyde Dehydroeburicoic acid 3-O-Acetyl-16alpha-hydroxydehydrotrametenolic acid (-)-pinoresinol Macrohyporia cocos Wolfiporia cocos
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Bioorganic Chemistry
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10.1016/J.BIOORG.2016.11.012
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16
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New Furan Derivatives from a Mangrove-Derived Endophytic Fungus Coriolopsis sp. J5.
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mangrove 1-[5-(1,2-dihydroxypropyl)furan-2-yl]pentan-1-one 5-(1-hydroxypentyl)furan-2-carboxylic acid 5-(3-methoxy-3-oxopropyl)furan-2-carboxylic acid 5-(3-hydroxypentyl)furan-2-carboxylic acid 2-Hydroxy-1-(5-(1-hydroxypentyl)-furan-2-yl)-propan-1-one 5-(1-hydroxypent-4-en-1-yl)furan-2-carboxylic acid (E)-5-(2-carboxyvinyl)-furan-2-carboxylic acid 1-[5-(2-hydroxypropanoyl)furan-2-yl]pentan-3-one Coriolopsis endophyte
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Molecules
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10.3390/MOLECULES22020261
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Creative Commons Attribution 4.0 International
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8
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Cycloartane triterpenoids and their glycosides from the rhizomes of Cimicifuga foetida
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Actaea cimicifuga GCMGJWLOGKSUGX-KKGXZNBCSA-N Cimiside A (3S)-3beta,24alpha,25-Trihydroxy-9,10-seco-5alpha-cycloartane-1(10),7,9(11)-triene-16,23-dione (3R,6S,8S,12R,15R,16R)-15-[(2R)-4-[(2R)-3,3-dimethyloxiran-2-yl]-4-oxobutan-2-yl]-3-hydroxy-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxytetracyclo[9.7.0.03,8.012,16]octadeca-1(18),10-dien-14-one (3S,6S,8S,12R,15R,16R)-15-[(2R)-4-[(2R)-3,3-dimethyloxiran-2-yl]-4-oxobutan-2-yl]-3-hydroxy-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxytetracyclo[9.7.0.03,8.012,16]octadeca-1(18),10-dien-14-one actein [(1S,2S,5R,7S,10R,12R,14R,15R,16R,17S,18R,21S,22S,24S)-21,22-dihydroxy-1,6,6,15,17,20,20-heptamethyl-7-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy-19,23-dioxaheptacyclo[13.10.0.02,12.05,10.010,12.016,24.018,22]pentacosan-14-yl] acetate [(1R,3R,4R,5R,6S,10S,12S,13S,16R,18S,21R)-8-(1,2-dihydroxy-2-methylpropyl)-4,6,12,17,17-pentamethyl-18-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy-9-oxahexacyclo[11.9.0.01,21.04,12.05,10.016,21]docos-7-en-3-yl] acetate (3S)-3beta,24beta,25-Trihydroxy-9,10-seco-5alpha-cycloartane-1(10),7,9(11)-triene-16,23-dione (3R,6S,8S,12R,15R,16R)-15-[(2R,5R)-5,6-dihydroxy-6-methyl-4-oxoheptan-2-yl]-3-hydroxy-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxytetracyclo[9.7.0.03,8.012,16]octadeca-1(18),10-dien-14-one 12β-acetoxycimigenol 3-O-β-D-xylopyranoside (1R,3R,6S,8R,12R,15R,16R,18S)-18-hydroxy-15-[(2R,5R)-5-hydroxy-6-methyl-4-oxohept-6-en-2-yl]-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxypentacyclo[9.7.0.01,3.03,8.012,16]octadec-10-en-14-one [(1R,3R,4R,5R,6R,8S,10S,12S,13S,16R,18S,21R)-8-hydroxy-4,6,12,17,17-pentamethyl-8-(2-methylpropanoyl)-18-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy-9-oxahexacyclo[11.9.0.01,21.04,12.05,10.016,21]docosan-3-yl] acetate (3S,6S,8S,12R,15R,16R)-15-[(2R,5R)-5,6-dihydroxy-6-methyl-4-oxoheptan-2-yl]-3-hydroxy-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxytetracyclo[9.7.0.03,8.012,16]octadeca-1(18),10-dien-14-one beta-D-Xylopyranoside, (3beta,15alpha,16alpha,23R,24S)-25-(acetyloxy)-16,23:16,24-diepoxy-15-hydroxy-9,19-cyclolanostan-3-yl, 3-acetate [[Q105240496|[(3R,4R,5R,6S)-6-[[(1S,2R,3S,4R,7R,9S,12R,14S,17R,18R,19R,21R,22S)-22-(2-acetyloxypropan-2-yl)-2-hydroxy-3,8,8,17,19-pentamethyl-23,24-dioxaheptacyclo[19.2.1.01,18.03,17.04,14.07,12.012,14]tetracosan-9-yl]oxy]-4,5-dihydroxyoxan-3-yl] acetate]] Cimicifuga foetida Actaea elata Actaea europaea
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Journal of Natural Products
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10.1021/NP500249V
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46
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Dolabellane diterpene glucosides from Chrozophora obliqua
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Chrozophora plicata (1R,3aS,4S,5Z,9R,11R,12aS)-6-(hydroxymethyl)-1-(2-hydroxypropan-2-yl)-3a-methyl-10-methylidene-1,2,3,4,7,8,9,11,12,12a-decahydrocyclopenta[11]annulene-4,9,11-triol [[Q105001038|(3R,4S,5S,6R)-2-[[(1R,3aS,4S,5Z,9R,12aS)-4-hydroxy-6-(hydroxymethyl)-1-(2-hydroxypropan-2-yl)-3a,12a-dimethyl-10-methylidene-2,3,4,7,8,9,11,12-octahydro-1H-cyclopenta[11]annulen-9-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol]] 2-[2-[4,9-Dihydroxy-6-(hydroxymethyl)-3a-methyl-10-methylidene-1,2,3,4,7,8,9,11,12,12a-decahydrocyclopenta[11]annulen-1-yl]propan-2-yloxy]-6-(hydroxymethyl)oxane-3,4,5-triol [[Q105384995|(2R,3R,4S,5S,6R)-2-[[(1R,3aS,4S,5Z,9R,12aS)-4-hydroxy-6-(hydroxymethyl)-1-(2-hydroxypropan-2-yl)-3a-methyl-10-methylidene-1,2,3,4,7,8,9,11,12,12a-decahydrocyclopenta[11]annulen-9-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol]] (3R,4S,5S,6R)-2-[2-[(1R,3aS,4S,5Z,9R,12aS)-4,9-dihydroxy-6-(hydroxymethyl)-3a,12a-dimethyl-10-methylidene-2,3,4,7,8,9,11,12-octahydro-1H-cyclopenta[11]annulen-1-yl]-2-methylpropoxy]-6-(hydroxymethyl)oxane-3,4,5-triol (2S,3R,4S,5S,6R)-2-[2-[(1R,3aS,4S,5Z,9R,12aS)-4,9-dihydroxy-6-(hydroxymethyl)-3a-methyl-10-methylidene-1,2,3,4,7,8,9,11,12,12a-decahydrocyclopenta[11]annulen-1-yl]propan-2-yloxy]-6-(hydroxymethyl)oxane-3,4,5-triol [[Q104990097|(2R,3R,4S,5S,6R)-2-[[(1R,3aS,4S,5Z,9S,10E,12aS)-4-hydroxy-6-(hydroxymethyl)-1-(2-hydroxypropan-2-yl)-3a,10-dimethyl-2,3,4,7,8,9,12,12a-octahydro-1H-cyclopenta[11]annulen-9-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol]] [[Q104990099|2-[[4-hydroxy-6-(hydroxymethyl)-1-(2-hydroxypropan-2-yl)-3a,10-dimethyl-2,3,4,7,8,9,12,12a-octahydro-1H-cyclopenta[11]annulen-9-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol]] [[Q104916961|(3R,4S,5S,6R)-2-[[(1R,3aS,4S,5Z,9S,10E,12aS)-4-hydroxy-6-(hydroxymethyl)-1-(2-hydroxypropan-2-yl)-3a,10-dimethyl-2,3,4,7,8,9,12,12a-octahydro-1H-cyclopenta[11]annulen-9-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol]] [[Q105384996|2-[[4-Hydroxy-6-(hydroxymethyl)-1-(2-hydroxypropan-2-yl)-3a-methyl-10-methylidene-1,2,3,4,7,8,9,11,12,12a-decahydrocyclopenta[11]annulen-9-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol]] Chrozophora obliqua
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Phytochemistry
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10.1016/0031-9422(94)85086-0
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14
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Phenolics from Glycyrrhiza glabra roots and their PPAR-gamma ligand-binding activity
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ligand binding liquorice 3-Hydroxy-9-methoxy-4-prenylpterocarpan (3R)-3-(2,3-Dihydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol Shinflavanone Kanzonol X Licoagrocarpin 4'-Methoxyglabridin (R)-Kanzonol Y 2-Propen-1-one, 1-[2,4-dihydroxy-3-(3-methyl-2-butenyl)phenyl]-3-(2,4-dihydroxyphenyl)-, (E)-; (2E)-1-[2,4-Dihydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(2,4-dihydroxyphenyl)-2-propen-1-one 4-[8-(hydroxymethyl)-8-methyl-2H,3H,4H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol 3,7-dihydroxy-2-[4-hydroxy-3-(3-methylbut-2-en-1-yl)phenyl]-2,3-dihydro-1-benzopyran-4-one kanzonol Y 2',3,4,4'-Tetrahydroxy-3',5-diprenyl-trans-chalcone 8-(hydroxymethyl)-8-methyl-2H,3H,4H-pyrano[2,3-f]chromen-3-ol (2S)-2-(2,2-dimethylchromen-6-yl)-7-hydroxy-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one glabrocoumarone a glabrol glabrene (2R)-1-[2,4-dihydroxy-3-(3-methylbut-2-enyl)phenyl]-3-(3,4-dihydroxyphenyl)-2-hydroxypropan-1-one 3'-Hydroxy-4'-O-methylglabridin 1-[2,4-Dihydroxy-3-(3-methylbut-2-enyl)phenyl]-3-[3,4-dihydroxy-5-(3-methylbut-2-enyl)phenyl]prop-2-en-1-one (R)-Glabridin (R)-Hispaglabridin A 3,3',4,4'-Tetrahydroxy-2-methoxy-5'-prenyl-trans-chalcone 3-(3,4-Dihydroxy-2-methoxyphenyl)-1-[3,4-dihydroxy-5-(3-methylbut-2-enyl)phenyl]prop-2-en-1-one hispaglabridin a (-)-Shinpterocarpin Morachalcone A 4,2',4',alpha-Tetrahydroxydihydrochalcone alpha,3,4,2',4'-Pentahydroxy-5,3'-diprenyl-alpha,beta-dihydro-trans-chalcone Kanzonol W echinatin (-)-vestitol 1-[2,4-Dihydroxy-3-(3-methylbut-2-enyl)phenyl]-3-(3,4-dihydroxyphenyl)-2-hydroxypropan-1-one 2-[4-hydroxy-3-(3-methylbut-2-en-1-yl)phenyl]-8,8-dimethyl-2H,3H-pyrano[2,3-f]chromen-4-one (+/-)-vestitol (3S)-8,8-dimethyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-ol 7,8-Dihydroxy-3-(4-methoxyphenyl)-6-(3-methylbut-2-enyl)chromen-4-one hispaglabridin B licochalcone b xambioona (2S)-2-(2,2-dimethylchromen-6-yl)-8,8-dimethyl-2,3-dihydropyrano[2,3-f]chromen-4-one licoflavone A (3R)-3-hydroxy-3-(2-hydroxy-4-methoxyphenyl)-8,8-dimethyl-2H-pyrano[2,3-f]chromen-4-one 4'-O-methylglabridin glabridin 5'-Formylglabridin (3S,8S)-8-(hydroxymethyl)-8-methyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-ol Dmdbp gancaonin L glabrone 3-(3,4-Dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one 1-[2,4-Dihydroxy-3-(3-methylbut-2-enyl)phenyl]-3-(8-hydroxy-2,2-dimethylchromen-6-yl)prop-2-en-1-one 6-methoxy-17,17-dimethyl-3,12,18-trioxapentacyclo[11.8.0.0²,¹⁰.0⁴,⁹.0¹⁴,¹⁹]henicosa-1(21),4,6,8,13,15,19-heptaene glabrocoumarin 3'-Hydroxy-4'-methoxyglabridin hispaglabridin b glabrol 3-(2-Hydroxy-4-methoxyphenyl)-3-hydroxy-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-4(3H)-one Arizonicanol A shinpterocarpin 8,8-dimethyl-2H,3H,4H-pyrano[2,3-f]chromen-3-ol (R)-2',4',7-Trihydroxy-3',8-diprenylisoflavan 1-(2,4-dihydroxyphenyl)-2-hydroxy-3-(4-hydroxyphenyl)propan-1-one hemileiocarpin (2R)-1-[2,4-dihydroxy-3-(3-methylbut-2-enyl)phenyl]-3-[3,4-dihydroxy-5-(3-methylbut-2-enyl)phenyl]-2-hydroxypropan-1-one CID 182171 4-[(3R,8S)-8-(hydroxymethyl)-8-methyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol euchrenone a5 3beta,7-Dihydroxy-2alpha-(4-hydroxy-3-prenylphenyl)-2,3-dihydro-4H-1-benzopyran-4-one 5-(8,8-dimethyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-yl)-2,4-dihydroxybenzaldehyde
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Bioorganic & Medicinal Chemistry
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10.1016/J.BMC.2009.11.027
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45
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Antimicrobial and immunomodulatory properties of prenylated xanthones from twigs of Garcinia staudtii
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Garcinia staudtii Staudtiixanthone B gartanin beta-sitosterol Staudtiixanthone A jacareubin garcinone B Staudtiixanthone D friedelin Staudtiixanthone C Demethylcalabaxanthone stigmasterol mangostin lupeol
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Bioorganic & Medicinal Chemistry
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10.1016/J.BMC.2009.06.009
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13
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Cytotoxic bisnor- and norditerpene dilactones having 7alpha,8alpha-epoxy-9,11-enolide substructure from Podocarpus macrophyllus D. DON.
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epoxy resins cytotoxicity Podocarpus macrophyllus (1S,2R,4S,5R,10S,11S,13R,14R,15R,18R)-14-hydroxy-5-[(2R)-2-hydroxy-1-[(S)-methylsulfinyl]propan-2-yl]-10,15-dimethyl-3,6,12,17-tetraoxahexacyclo[8.7.1.02,4.04,9.011,13.015,18]octadec-8-ene-7,16-dione (1S,2R,4S,5R,10S,14S,17R)-5-[(2R)-2-hydroxy-1-[(S)-methylsulfinyl]propan-2-yl]-10,14-dimethyl-3,6,16-trioxapentacyclo[8.6.1.02,4.04,9.014,17]heptadec-8-ene-7,15-dione Podolactone B Nagilactone G (1S,2R,4S,5R,10S,11S,13R,14S,15R,18R)-14-hydroxy-5-[(2R)-2-hydroxy-1-[(S)-methylsulfinyl]propan-2-yl]-10,15-dimethyl-3,6,12,17-tetraoxahexacyclo[8.7.1.02,4.04,9.011,13.015,18]octadec-8-ene-7,16-dione Makilactone L Makilactone M Makilactone F Rakanmakilactone H Makilactone K Sellowin B (1S,2R,4S,5R,10S,12S,14R,15R,18R)-5-[(2R)-2-hydroxy-1-[(S)-methylsulfinyl]propan-2-yl]-10,15-dimethyl-3,6,13,17-tetraoxahexacyclo[8.7.1.02,4.04,9.012,14.015,18]octadec-8-ene-7,16-dione Makilactone J Makilactone N Podolactone B,2-deepoxy-15,16-dideoxy- Makilactone I Makilactone H Salignone M (1S,2R,4S,5R,10S,11S,13R,14R,15R,18R)-5-[(2S)-1,2-dihydroxypropan-2-yl]-14-hydroxy-10,15-dimethyl-3,6,12,17-tetraoxahexacyclo[8.7.1.02,4.04,9.011,13.015,18]octadec-8-ene-7,16-dione inumakilactone B Podolactone D Makilactone G Makilactone E (1S,2R,4S,5R,10S,11S,13R,14R,15R,18R)-14-hydroxy-5-[(1R)-1-hydroxyethyl]-10,15-dimethyl-3,6,12,17-tetraoxahexacyclo[8.7.1.02,4.04,9.011,13.015,18]octadec-8-ene-7,16-dione (1S,2R,4S,5R,10S,11S,13R,15S,18R)-10,15-dimethyl-5-[(1R)-1-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyethyl]-3,6,12,17-tetraoxahexacyclo[8.7.1.02,4.04,9.011,13.015,18]octadec-8-ene-7,16-dione Makilactone Q
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Chemical & Pharmaceutical Bulletin
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10.1248/CPB.57.668
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26
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Chromone and chromanone glucosides from Hypericum sikokumontanum and their anti-Helicobacter pylori activities
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Helicobacter pylori Hypericum sikokumontanum methyl (1S,3R,4R,5R)-3-[(Z)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-1,4,5-trihydroxycyclohexane-1-carboxylate (1R,3R,4S,5R)-Butyl 3-(((E)-3-(3,4-dihydroxyphenyl)acryloyl)oxy)-1,4,5-trihydroxycyclohexanecarboxylate 2-[(2R)-butan-2-yl]-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one (2S,3S)-5,7-dihydroxy-3-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one isomangiferin 4'-O-beta-D-glucosyl-cis-p-coumaric acid 8-beta-D-Glucopyranosyl-5,7-dihydroxy-2-isopropylchromone 3Eec4Q65S4 phenylethyl beta-D-glucopyranoside quercetin quercitrin (R)-Linaryl beta-D-glucopyranoside 5,7-dihydroxy-3-methylchromen-4-one (2S,3S)-3-ethyl-5,7-dihydroxy-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one Hyperxanthone Butyl chlorogenate avicularin Astragalin lathodoratin Takanechromone A Benzoyl-beta-D-glucoside (E)-chlorogenic acid Neochlorogenic acid methyl ester 2-Acetylheperoside hyperoside 4-O-beta-D-glucosyl-trans-4-coumaric acid Takanechromone B isoquercetin methyl chlorogenate 1,3,5-trihydroxyxanthone 4-(beta-D-glucopyranosyloxy)-3-methoxybenzoic acid Takanechromone C neochlorogenic acid CID 14484636
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Phytochemistry
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10.1016/J.PHYTOCHEM.2008.11.006
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34
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BACE1 inhibitory effects of lavandulyl flavanones from Sophora flavescens
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Sophora flavescens Megaselia flavescens (2R)-5,7-dihydroxy-2-(2-hydroxyphenyl)-8-[(2S)-5-methyl-2-prop-1-en-2-ylhex-4-enyl]-2,3-dihydrochromen-4-one (2R)-5,7-dihydroxy-8-[(2R)-5-hydroxy-5-methyl-2-prop-1-en-2-ylhexyl]-2-(2-hydroxyphenyl)-2,3-dihydrochromen-4-one (2S)-2'-methoxykurarinone Isoxanthohumol 2'-Methoxykurarinone Marini leachianone A (2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2S)-5-methyl-2-prop-1-en-2-ylhex-4-enyl]-2,3-dihydrochromen-4-one Kurarinone leachianone A 2-(2,4-Dihydroxyphenyl)-7-hydroxy-8-(5-hydroxy-5-methyl-2-prop-1-en-2-ylhexyl)-5-methoxy-2,3-dihydrochromen-4-one kurarinol Kushenol A (2S)-(-)-kurarinone
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Bioorganic & Medicinal Chemistry
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10.1016/J.BMC.2008.05.080
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16
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New cytotoxic diarylheptanoids from the rhizomes of Alpinia officinarum
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cytotoxicity (5R)-7-(4-hydroxy-3-methoxyphenyl)-5-methoxy-1-phenylheptan-3-one (4E)-7-(4-hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one Alpinia officinarum (5R)-5-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-phenylheptan-3-one 7-(4-hydroxyphenyl)-5-methoxy-1-phenylheptan-3-one 7-(4-Hydroxy-3-methoxyphenyl)-5-methoxy-1-phenyl-3-heptanone 2-hydroxy-1,7-diphenylhept-4-en-3-one 1-(4-Hydroxy-3-methoxyphenyl)-7-phenylheptane-3,5-diol 1,7-diphenylheptane-3,5-diol 4-Hepten-3-one, 1,7-diphenyl- 5-hydroxy-7-(4-hydroxyphenyl)-1-phenylheptan-3-one (E)-1,7-diphenylhept-4-en-3-one 1-(4-Hydroxyphenyl)-5-methoxy-7-(3-methoxy-4-hydroxyphenyl)-3-heptanone 2-benzyl-5-(2-phenylethyl)furan Alpinoid D (E)-7-(4-hydroxyphenyl)-1-phenylhept-4-en-3-one (5S)-5-Methoxy-7-(4-hydroxyphenyl)-1-phenyl-3-heptanone 7-(4-Hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one 7-(4-Hydroxy-3-methoxy-phenyl)-1-(4-hydroxy-phenyl)-hept-4-en-3-one (2S,4E)-2-hydroxy-1,7-diphenylhept-4-en-3-one (3S,5R)-1-(4-hydroxy-3-methoxyphenyl)-7-phenylheptane-3,5-diol (5S)-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-5-methoxyheptan-3-one (5s)-5-Hydroxy-7-(4-hydroxyphenyl)-1-phenylhept-3-one 5-hydroxy-1,7-diphenylheptan-3-one 7-(4-Hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-5-hydroxy-3-heptanone (3R,5R)-1,7-diphenylheptane-3,5-diol (5S)-5-methoxy-1,7-diphenylheptan-3-one 5-methoxy-1,7-diphenylheptan-3-one 5-Hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-phenyl-3-heptanone 7-(4-hydroxyphenyl)-1-phenylhept-4-en-3-one (5R)-5-hydroxy-1,7-diphenylheptan-3-one (5S)-1-(4-Hydroxyphenyl)-5-hydroxy-7-(3-methoxy-4-hydroxyphenyl)-3-heptanone 1-(4-Hydroxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)-4-hepten-3-one
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Planta Medica
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10.1055/S-2008-1034345
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21
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New neo-clerodane diterpenoid alkaloids from Scutellaria barbata with cytotoxic activities
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Scutellaria barbata Scutebarbatine L(rel) Scutebarbatine K(rel) [(1R,2S,3R,4S,4aS,8aR)-2-acetyloxy-3-hydroxy-3,4,8,8a-tetramethyl-4-[(E)-2-(5-oxo-2H-furan-3-yl)ethenyl]-2,4a,5,6-tetrahydro-1H-naphthalen-1-yl] pyridine-3-carboxylate [(1R,2S,3R,4S,4aS,8aR)-2-[(2R)-2-acetyloxy-3-methylbutanoyl]oxy-3-hydroxy-3,4,8,8a-tetramethyl-4-[(E)-2-(5-oxo-2H-furan-3-yl)ethenyl]-2,4a,5,6-tetrahydro-1H-naphthalen-1-yl] pyridine-3-carboxylate Scutebarbatine I(rel) Scutebarbatine J(rel) [(1R,2S,3R,4R,4aS,8aR)-2-[(2R)-2-acetyloxy-3-methylbutanoyl]oxy-3-hydroxy-3,4,8,8a-tetramethyl-4-[(E)-2-(5-oxo-2H-furan-3-yl)ethenyl]-2,4a,5,6-tetrahydro-1H-naphthalen-1-yl] pyridine-3-carboxylate
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Chemical & Pharmaceutical Bulletin
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10.1248/CPB.56.207
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7
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New prenylated aeruginosin, microphycin, anabaenopeptin and micropeptin analogues from a Microcystis bloom material collected in Kibbutz Kfar Blum, Israel
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Israel Microcystis Micropeptin KB1048 [[Q104203216|Methyl 4-[[5-benzyl-15-[3-(diaminomethylideneamino)propyl]-21-methoxy-4,11-dimethyl-3,6,9,13,16,22-hexaoxo-2,8-di(propan-2-yl)-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]amino]-3-(hexanoylamino)-4-oxobutanoate]] Micropeptin KB970C 3-(4-hydroxyphenyl)-2-[({2,5,11,14-tetrahydroxy-6-[2-(4-hydroxyphenyl)ethyl]-12-isopropyl-7-methyl-8-oxo-9-(2-phenylethyl)-3-(sec-butyl)-1,4,7,10,13-pentaazacyclononadeca-1,4,10,13-tetraen-15-yl}-C-hydroxycarbonimidoyl)amino]propanoic acid Micropeptin KB1046 3-[(3S,6S,9S,12S,15S,18S,21S,26aS)-6,9,12-tribenzyl-1,4,7,10,13,16,19-heptahydroxy-15,21-dimethyl-3-(2-methylpropyl)-22-oxo-3H,6H,9H,12H,15H,18H,21H,24H,25H,26H,26aH-pyrrolo[1,2-a]1,4,7,10,13,16,19,22-octaazacyclotetracosan-18-yl]propanimidic acid [[Q104203215|4-[[5-Benzyl-8-butan-2-yl-15-[3-(diaminomethylideneamino)propyl]-21-methoxy-4,11-dimethyl-3,6,9,13,16,22-hexaoxo-2-propan-2-yl-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]amino]-3-(hexanoylamino)-4-oxobutanoic acid]] Micropeptin KB970B [[Q104203180|N-[5-benzyl-2-butan-2-yl-21-methoxy-4,11-dimethyl-15-(2-methylpropyl)-3,6,9,13,16,22-hexaoxo-8-propan-2-yl-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]-2-[[2-hydroxy-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide]] Micropeptin KB970A Micropeptin KB984 Micropeptin KB992 Anabaenopeptin KB906 Anabaenopeptin KB899 [[Q104203214|Methyl 4-[[5-benzyl-8-butan-2-yl-15-[3-(diaminomethylideneamino)propyl]-21-hydroxy-4,11-dimethyl-3,6,9,13,16,22-hexaoxo-2-propan-2-yl-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]amino]-3-(hexanoylamino)-4-oxobutanoate]] [[Q104203167|N-[5-benzyl-8-butan-2-yl-21-hydroxy-15-[(4-hydroxycyclohex-2-en-1-yl)methyl]-4,11-dimethyl-3,6,9,13,16,22-hexaoxo-2-propan-2-yl-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]-2-[[2-hydroxy-3-(4-hydroxyphenyl)propanoyl]amino]pentanediamide]] [[Q104203227|Methyl 4-[[5-benzyl-8-butan-2-yl-15-[3-(diaminomethylideneamino)propyl]-21-methoxy-4,11-dimethyl-3,6,9,13,16,22-hexaoxo-2-propan-2-yl-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]amino]-3-(butanoylamino)-4-oxobutanoate]] [[Q104203204|Methyl 4-[[5-benzyl-8-butan-2-yl-15-[3-(diaminomethylideneamino)propyl]-21-methoxy-4,11-dimethyl-3,6,9,13,16,22-hexaoxo-2-propan-2-yl-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]amino]-3-(hexanoylamino)-4-oxobutanoate]] Micropeptin KB956 [[Q104203251|4-[[5-Benzyl-8-butan-2-yl-15-[3-(diaminomethylideneamino)propyl]-21-hydroxy-4,11-dimethyl-3,6,9,13,16,22-hexaoxo-2-propan-2-yl-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]amino]-3-(butanoylamino)-4-oxobutanoic acid]] Micropeptin KB928 [[Q104203231|5-(Diaminomethylideneamino)-2-[[3,12-di(butan-2-yl)-6-[2-(4-hydroxyphenyl)ethyl]-7-methyl-2,5,8,11,14-pentaoxo-9-(2-phenylethyl)-1,4,7,10,13-pentazacyclononadec-15-yl]carbamoylamino]pentanoic acid]] Aeruginosin KB676 3-[6,9,12-tribenzyl-1,4,7,10,13,16,19-heptahydroxy-15,21-dimethyl-3-(2-methylpropyl)-22-oxo-3H,6H,9H,12H,15H,18H,21H,24H,25H,26H,26aH-pyrrolo[1,2-a]1,4,7,10,13,16,19,22-octaazacyclotetracosan-18-yl]propanimidic acid [[Q104203188|Methyl 4-[[2,8-di(butan-2-yl)-5-[(3-chloro-4-hydroxyphenyl)methyl]-15-[3-(diaminomethylideneamino)propyl]-21-methoxy-4,11-dimethyl-3,6,9,13,16,22-hexaoxo-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]amino]-3-(hexanoylamino)-4-oxobutanoate]] (3aS,7aS)-1-[(2S)-2-{[1,2-dihydroxy-3-(4-hydroxyphenyl)propylidene]amino}-3-phenylpropanoyl]-6-hydroxy-N-{4-[N-(3-methylbut-2-en-1-yl)carbamimidamido]butyl}-octahydroindole-2-carboximidic acid
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Marine Drugs
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10.3390/MD13042347
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Creative Commons Attribution 4.0 International
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14
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Constituents of Cannabis sativa L. XVII. A review of the natural constituents
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Cannabis sativa p-α-dimethyl styrene (E)-isoeugenol heptanal sabinene nonadecane eugenol piperitenone undecane dimethylamine campest-4-en-3-one L-serine Cannabidiol-3-monomethyl ether aldehydo-D-ribose (2R)-6-methyl-2-(4-methylcyclohex-3-en-1-yl)hept-5-en-2-ol 2-undecanone tridecanal 2-methyldotriacontane pulegone behenic acid γ‑terpinene Cannabielsoic acid A decanal methanol inositol (+/-)-4-terpineol (6Z)-β-farnesene phenyl-Alanine L-aspartic acid 2-dodecanone anethole (+)-beta-selinene Phenol, 3-[2-(4-hydroxyphenyl)ethyl]-5-methoxy- cannabinol p-cymen-8-ol icos-2-enoic acid p-cymene glycerol farnesylacetone levo-α-cedrene ribitol (6E)-2,6-dimethyl-10-methylidenedodeca-2,6-diene (E)-beta-terpineol galactitol α-thujene tricosane humulene Cannabidivarinic acid L-arabinopyranose heptadecane rhamnose (aldehydo) 1-octanol caryophyllene alcohol α-phellandrene 9-methyloctacosane 6-Methyl-9-isopropenyl-3-pentyldibenzofuran-1-ol succinic acid cannabichromene fenchone D-sorbitol (6S,9R)-vomifoliol Thalictiin L-arginine terpinolene D-methionine (±)-bornyl acetate icosa-2,4-dienoic acid aldehydo-D-mannose 3,6,6,9-tetramethylbenzo[c]chromen-1-ol trigonelline β-bisabolene α-selinene decane docosane hexyl acetate linoleic acid aldehydo-D-xylose trans-zeatin pentadecane caryophyllene geranylacetone neral cannabichromevarin cannabidiolic acid L-tyrosine Cannabielsoic acid B tetradecane 1D-1-O-Methyl-myo-inositol dotriacontane L-leucine (6E)-(-)-nerolidol hordenine (11Z,14Z)-icosadienoic acid palmitoleic acid isobutylamine 1-Ethenyl-1,2-dimethyl-4-propan-2-ylidene-2-prop-1-en-2-ylcyclohexane cannabigerovarin hexadecane apigetrin D-Aspartic acid (±)-limonene phenylalanine 1-methoxy-6,6,9-trimethyl-3-pentylbenzo[c]chromene 3-methylpentacosane hentriacontane pentanal camphene D-cystine methyl salicylate (Z)-anethole γ-elemene 3-methyltricosane cannabichromenic acid 1-Methyl-4-(6-methylhept-6-en-2-yl)cyclohexa-1,4-diene Cannabigerovarinic acid 2-heptanone alpha-linolenic acid L-Alanine isocaryophyllene nerol oct-1-en-3-ol 3-methylhentriacontane (2-Hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl)acetic acid D-fructopyranose D-(-)-mannitol (+/-)-linalool (1E,8E)-2,6,6,9-tetramethylcycloundeca-1,4,8-triene ergosterol (1R)-endo-(+)-fenchol 3-methylheptacosane (+)-γ-cadinene camphene hydrate oleic acid vanillic acid 2-decanone 4-carene piperitenone oxide β-caryophyllene oxide glucaric acid safranal glycine choline palmitic acid acetone (4E,7E)-1,5,9,9-Tetramethyl-12-oxabicyclo[9.1.0]dodeca-4,7-diene 6-methyl-5-hepten-2-one pyrrolidine cetyl alcohol dihydrocarvone Cannabidivarin beta-sitostenone 2-phenethylamine α-terpinene (3E)-β-ocimene ethanol (2S,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol 3-Decen-5-one raffinose stearic acid cannabielsoin D-glucosamine (±)-3-carene tridecane Cannabiripsol lauryl aldehyde myrcene Acetylcannabispirol isocitric acid tryptophan β-humulene methyl acetate pinocarvone azelaic acid caprylaldehyde guaiol monoethanolamine octatriacontane D-phenylalanine dodecane epi-beta-santalene cannabinodiol Cannabisativine pentane-1,2,3,4,5-pentol ammonia trans-β-ionone carvacrol (+)-carvone (1R,2S,7S,8S)-1,3-dimethyl-8-propan-2-yltricyclo[4.4.0.02,7]dec-3-ene 4-ethylbenzaldehyde sedoheptulose methyl linoleate 4-hydroxybenzoic acid camphor L-lysine L-glutamic acid heptatriacontane epi-Friedelanol 3-octanol α-D-glucopyranose Cannabichromanone (4S)-4-hydroxy-4-[(E,3R)-3-hydroxybut-1-enyl]-3,3,5-trimethylcyclohexan-1-one benzyl acetate cis-Calamenene 2-methylhentriacontane octadecane Benzene, (2-methyl-2-propenyl)- L-histidine myristic acid pentatriacontane 2-pentadecanone hexyl butyrate β-D-glucopyranose 3-phenyl propionic acid L-cystine phosphoric acid arachidic acid (-)-alpha-curcumene pentacosane (E)-cinnamic acid tetratriacontane aldehydo-D-galactose nonanal isobutyraldehyde Cannabifuran octacosane (E)-p-coumaric acid DL-1-phenethylamine stigmasterol D-xylopyranose methylamine cannabigerolic acid monomethyl ether nonatriacontane heneicosane 3-methylhenicosane glyceric acid D-ribopyranose isononacosane (E)-phytonadione Gal(a1-4)a-Ido cannabicyclol alpha-terpineol Alloaromadendren Cannabicyclolic acid β-humulene 2-methyltetracosane D-Alanine D-arabinonic acid muscarine β-cyclocitral (-)-alpha-gurjunene erythritol L-valine ethenyltrimethylazanium orientin D-gluconic acid cadaverine geraniol canniprene undecanal (4-ethylphenyl)methyl acetate sucrose farnesol hexanal methyl palmitate cannabidiol tetracosane sec-butylamine (5E,9E)-farnesyl acetone (R)-beta-bisabolene Piperitone oxide Cannabichromevarinic acid L-methionine hexacosane methyl eugenol cannabitriol (unspec.) (11E)-11-eicosenoic acid heptacosane aldehydo-D-arabinose (+)-δ-cadinene Cannabispiran nonacosane Cannabispirenone phytol vitexin 2-O-beta-D-glucoside perillene (±)-β-citronellol D-galacturonic acid tyramine 2-amino-2-deoxy-D-galactopyranose Sativic acid L-isoleucine citric acid nonane octyl hexanoate piperidine β-D-Galactopyranuronic acid hexatriacontane 7-Methoxy-9,10-dihydrophenanthrene-3,5-diol cannabigerol 4-Ethylbenzenepropanoic acid Gigantol alpha-pinene ethylamine elaidolinolenic acid n-butylamine 1-nonanol Cannabispirol pinocarveol tritriacontane L-Threonine (3Z)-β-ocimene beta-pinene malonic acid hexyl hexanoate Cannabicoumaronone acetaldehyde icosane L-proline ferulic acid diethylamine 3-octanone dihydroactinidiolide friedelin xylitol CID 16396350 D-threonic acid (E)-(-)-α-bergamotene L-rhamnopyranose cannabigerolic acid Cannabinolic acid keto-D-fructose (2E,6Z)-farnesol gamma-eudesmol hexane-1,2,3,4,5,6-hexol (-)-beta-curcumene histamine 2-methylhexacosane Nerolidol cannabivarin triacontane cannabidiorcol (-)-α-cubebene DL-malic acid β-phellandrene (S)-pyroglutamic acid ethane β-maltose cedr-8-ene beta-sitosterol cannabicitran Humulene oxide II tetrahydrocannabinol isoeugenol (+)-cis-sabinol Ledol campesterol (-)-γ-cadinene D-glyceric acid
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Journal of Natural Products
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10.1021/NP50008A001
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354
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New natural epothilones from Sorangium cellulosum, strains So ce90/B2 and So ce90/D13: isolation, structure elucidation, and SAR studies
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Sorangium cellulosum Sorangium (1Z,3S,5E,10S,11R)-2,6,10-trimethyl-1-(2-methylthiazol-4-yl)trideca-1,5-diene-3,11-diol epothilone H2 (1S,3S,7S,10R,11R,12S,16R)-7,11-dihydroxy-3-[(E)-3-hydroxy-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-8,8,10,12-tetramethyl-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione (1S,3S,7S,8S,10R,11R,12S,16R)-7,11-dihydroxy-8,10,12-trimethyl-3-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione epothilone C5 Epothilone C8 3-Hydroxy-5-methoxy-2,6-dimethyl-7-(2-methyl-1,3-thiazol-4-yl)hept-6-enoic acid trans-epothilone C1 Epothilone K Epothilone C6 (4R,5S,6S,10Z,13S,14E)-2,4,6,14-Tetramethyl-5,13-dihydroxy-15-(2-methyl-4-thiazolyl)-10,14-pentadecadiene-3-one (4S,8Z,11S,12E)-11-hydroxy-4,12-dimethyl-13-(2-methyl-1,3-thiazol-4-yl)trideca-8,12-dien-3-one epothilone C6 epothilone A8 Epothilone H2 (1S,3S,7S,8R,10R,11R,12S,16R)-7,11-dihydroxy-8,10,12-trimethyl-3-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione Epothilone B10 (4S,8Z,11S,12E)-11-hydroxy-4,8,12-trimethyl-13-(2-methyl-1,3-thiazol-4-yl)trideca-8,12-dien-3-one (1S,3S,7S,10R,11R,12S,16R)-7,11-dihydroxy-3-[(E)-1-[2-(hydroxymethyl)-1,3-thiazol-4-yl]prop-1-en-2-yl]-8,8,10,12-tetramethyl-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione Epothilone C9 (1E,3S,5Z,10S,11R)-2,10-dimethyl-1-(2-methyl-1,3-thiazol-4-yl)trideca-1,5-diene-3,11-diol epothilone A2 (4S,7R,8S,9S,11S,15Z,18S)-4,8-dihydroxy-5,5,7,9,11-pentamethyl-18-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclooctadec-15-ene-2,6-dione utidelone (6E)-3,5-Dihydroxy-6-methyl-7-(2-methyl-4-thiazolyl)-6-heptenoic acid Epothilone I3 patupilone (1S,3S,7S,10R,11R,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(E)-1-(2-methyl-1,3-oxazol-4-yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione (4S,5R,7R,8S,9S,11R,15Z,18S)-4,8-dihydroxy-5,7,9,11,15-pentamethyl-18-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclooctadec-15-ene-2,6-dione epothilone D5 Epothilone F (1S,3S,7S,10R,11R,12S,16R)-3-[(E)-1-(2-ethyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-7,11-dihydroxy-8,8,10,12,16-pentamethyl-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione (1S,3S,7S,10R,11R,12S,16R)-7,11-dihydroxy-8,8,10,12-tetramethyl-3-[(E)-1-(2-methyl-1,3-oxazol-4-yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione epothilone H1 Methoxycarboxylic acid 42 Epothilone I2 Epothilone I1 Epothilone G2 epothilone a (E,2S,3R,5R)-3,5-dihydroxy-2,6-dimethyl-7-(2-methyl-1,3-thiazol-4-yl)hept-6-enoic acid epothilone C1 Epothilone C4 Epothilone E (4S,7R,8S,9S,11S,15Z,18S)-4,8-dihydroxy-5,5,7,9,11,15-hexamethyl-18-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclooctadec-15-ene-2,6-dione Epothilone C3 Epothilone C7 (1S,3S,7S,10R,11R,12S,16R)-7,11-dihydroxy-8,8,10,12-tetramethyl-3-[(E)-2-(2-methyl-1,3-thiazol-4-yl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione (E,3S)-3-methoxy-4-methyl-5-(2-methyl-1,3-thiazol-4-yl)pent-4-enoic acid epothilone C9 epothilone C7 (4S,5R,7R,11Z,14S)-4-hydroxy-5,7,11-trimethyl-14-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclotetradec-11-ene-2,6-dione epothilone c Epothilone G1 (6E)-2,6-Dimethyl-3,5-dihydroxy-7-(2-methyl-4-thiazolyl)-6-heptenoic acid epothilone D2 epothilone C8 (E,3S,5R)-3,5-dihydroxy-6-methyl-7-(2-methyl-1,3-thiazol-4-yl)hept-6-enoic acid (1S,3S,7S,10R,11R,12S,16R)-7,11-dihydroxy-3-[(E)-1-[2-(hydroxymethyl)-1,3-thiazol-4-yl]prop-1-en-2-yl]-8,8,10,12,16-pentamethyl-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione Epothilone I4 Epothilone C 7,11-Dihydroxy-8,8,10,12,16-pentamethyl-3-[1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione (4S,5R,7S,11Z,14S)-4-hydroxy-5,7-dimethyl-14-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclotetradec-11-ene-2,6-dione 4-desmethylepothilone D Epothilone C2 (Z)-3-hydroxy-5-methoxy-2,6-dimethyl-7-(2-methylthiazol-4-yl)hept-6-enoic acid (4S,7R,8S,9R,13Z,16S)-4,8-dihydroxy-5,5,7,9-tetramethyl-16-[(E)-2-(2-methyl-1,3-thiazol-4-yl)ethenyl]-1-oxacyclohexadec-13-ene-2,6-dione Epothilone A9 trans-epothilone C2 (4S,5R,7R,8S,9S,11R,15Z,18S)-4,8-dihydroxy-5,7,9,11-tetramethyl-18-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclooctadec-15-ene-2,6-dione (4S,11S,12E)-11-hydroxy-4,8-dimethyl-13-(2-methyl-1,3-thiazol-4-yl)trideca-8,12-dien-3-one epothilone A1 (4S,5R,7R,8S,9S,18S)-4,8-dihydroxy-5,7,9,11,15-pentamethyl-18-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclooctadec-15-ene-2,6-dione (4S,7R,8S,9S,15S,16R)-4,8,15-trihydroxy-5,5,7,9-tetramethyl-16-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadec-13-ene-2,6-dione (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-3-[3-hydroxy-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-8,8,10,12-tetramethyl-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione (4S,7R,8S,9S,16S)-4,8-dihydroxy-5,5,7,9-tetramethyl-16-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadeca-11,13-diene-2,6-dione (4S,5S,7R,8S,9S,18S)-4,8-dihydroxy-5,7,9,11-tetramethyl-18-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclooctadec-15-ene-2,6-dione (4S,7R,8S,9S,18S)-4,8-dihydroxy-5,5,7,9,11-pentamethyl-18-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclooctadec-15-ene-2,6-dione (4S,11S,12E)-11-hydroxy-4-methyl-13-(2-methyl-1,3-thiazol-4-yl)trideca-8,12-dien-3-one (4S,5S,7R,8S,9S,18S)-4,8-dihydroxy-5,7,9,11,15-pentamethyl-18-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclooctadec-15-ene-2,6-dione (4S,14S)-4-hydroxy-5,7-dimethyl-14-[(E)-2-(2-methyl-1,3-thiazol-4-yl)ethenyl]-1-oxacyclotetradec-11-ene-2,6-dione (4S,7R,8S,16S)-4,8-dihydroxy-5,5,7-trimethyl-16-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadec-13-ene-2,6-dione (4S,8R,9S,16S)-4,8-dihydroxy-5,5,9-trimethyl-16-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadec-13-ene-2,6-dione (4R,5S,6S,13S,14E)-5,13-dihydroxy-2,2,4,6-tetramethyl-15-(2-methyl-1,3-thiazol-4-yl)pentadeca-10,14-dien-3-one (4S,7R,8S,9S,18S)-4,8-dihydroxy-5,5,7,9,11,15-hexamethyl-18-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclooctadec-15-ene-2,6-dione (4S,7R,8S,9S,16S)-4,8-dihydroxy-16-[3-hydroxy-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-5,5,7,9-tetramethyl-1-oxacyclohexadec-13-ene-2,6-dione (4S,7R,8S,9S,16S)-4,8-dihydroxy-5,5,7,9-tetramethyl-16-[(E)-2-(2-methyl-1,3-thiazol-4-yl)ethenyl]-1-oxacyclohexadec-13-ene-2,6-dione (4S,7R,8S,9S,16S)-4,8-dihydroxy-5,5,7,9-tetramethyl-16-[(E)-1-(2-methyl-1,3-oxazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadec-13-ene-2,6-dione epothilone B10 (4S,7R,8S,9S,18S)-4,8-dihydroxy-5,5,7,9-tetramethyl-18-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclooctadec-15-ene-2,6-dione (4S,7R,8R,9E,16S)-4,8-dihydroxy-5,5,7,9-tetramethyl-16-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadeca-9,13-diene-2,6-dione epothilone D1 (4S,5R,7R,8S,9S,16S)-4,8-dihydroxy-5,7,9-trimethyl-16-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadec-13-ene-2,6-dione (4S,5S,7R,8S,9S,16S)-4,8-dihydroxy-5,7,9-trimethyl-16-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadec-13-ene-2,6-dione Epothilone A1 4,8-Dihydroxy-5,5,7,9-tetramethyl-16-[2-(2-methyl-1,3-thiazol-4-yl)ethenyl]-1-oxacyclohexadec-13-ene-2,6-dione Epothilone D1 4,8-Dihydroxy-5,7,9,11-tetramethyl-18-[1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclooctadec-15-ene-2,6-dione 4,8-Dihydroxy-5,5,7,9,11-pentamethyl-18-[1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclooctadec-15-ene-2,6-dione epothilone I6 4-Hydroxy-5,7-dimethyl-14-[2-(2-methyl-1,3-thiazol-4-yl)ethenyl]-1-oxacyclotetradec-11-ene-2,6-dione 5,13-Dihydroxy-2,2,4,6-tetramethyl-15-(2-methyl-1,3-thiazol-4-yl)pentadeca-10,14-dien-3-one epothilone I5 3-[1-(2-Ethyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-7,11-dihydroxy-8,8,10,12-tetramethyl-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione 11-Hydroxy-4-methyl-13-(2-methyl-1,3-thiazol-4-yl)trideca-8,12-dien-3-one 11-Hydroxy-4,8-dimethyl-13-(2-methyl-1,3-thiazol-4-yl)trideca-8,12-dien-3-one
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Journal of Natural Products
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10.1021/NP000629F
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114
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Medicinal foodstuffs. XVIII. Phytoestrogens from the aerial part of Petroselinum crispum MIll. (Parsley) and structures of 6"-acetylapiin and a new monoterpene glycoside, petroside
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parsley Linum salsoloides apiin Astragalin apiole myristicin Petroside 7-O-B-D-Glucopyranoside apigetrin trifolin Apioside Icariside F2 Cnidilin 2-(Hydroxymethyl)-6-[(3-hydroxy-4-methyl-1-prop-1-en-2-yl-7-oxabicyclo[2.2.1]heptan-2-yl)oxy]oxane-3,4,5-triol isoimperatorin Diosmetin 7-O-beta-D-glucopyranoside 6-Acetylapiin apigetrin 3-[3-(3,4-Dihydroxyphenyl)prop-2-enoyloxy]-1,4,5-trihydroxy-cyclohexanecarboxylic acid Linum suffruticosum
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Chemical & Pharmaceutical Bulletin
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10.1248/CPB.48.1039
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24
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Enzymatic inhibitory activity and trypanocidal effects of extracts and compounds from Siphoneugena densiflora O. Berg and Vitex polygama Cham
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Siphoneugena densiflora Vitex agnus-castus Vitex polygama 3,3'-di-O-methylquercetin syringic acid (2S,3R,5R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one shidasterone Eschweilenol C vanillic acid UDYKDZHZAKSYCO-HZJXWCEWSA-N acacetin 3',4',5,7-tetrahydroxy-3-methoxyflavone kaempferol 3,7,4'-trimethyl ether (2S,3R,10R,13R,17S)-2,3-dihydroxy-10,13-dimethyl-17-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]-1,2,3,4,5,9,11,12,16,17-decahydrocyclopenta[a]phenanthren-6-one (4aS,6aS,6bR,10S,11R,12aR)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid arjunolic acid 5-(hydroxymethyl)-2-furaldehyde 5-Hydroxy-3,6,7-trimethoxy-2-(4-methoxyphenyl)chromen-4-one 4-hydroxybenzoic acid ellagic acid polypodine B Casuarinin oleanolic acid tormentic acid chryseriol Vitex limonifolia
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Zeitschrift für Naturforschung C
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10.1515/ZNC-2008-5-611
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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported
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25
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Chemical composition and antibacterial activity of the essential oils from Launaea resedifolia L
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Launaea resedifolia (Z)-3-dodecene dibutyl phthalate (+)-Limonene diepoxide ethyl (E)-hept-2-enoate heptanal cetyl alcohol butyl octyl phthalate capryl caprate (E)-octadec-11-enal (6Z)-oct-6-en-2-one dioctyl adipate dimethyl glutarate 3,4-Dimethylcyclohexanol essential oil (±)-bornyl acetate di-N-octyl phthalate eucalyptol β-caryophyllene oxide (+/-)-linalool 1-octanol
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Organic and medicinal chemistry letters
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10.1186/2191-2858-2-2
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19
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Diterpenoids and sesquiterpenoids from the roots of Illicium majus
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Illicium majus (1S,4aS,10aR)-7-[(2R)-1,2-dihydroxypropan-2-yl]-1,4a-dimethyl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylic acid MajusanicacidD [(1S,2R,5S,6R,9S,10R,13R)-5,13-dihydroxy-2,6,10-trimethyl-11-oxo-8-oxatetracyclo[7.3.1.01,5.06,10]tridecan-9-yl] 2-methyl-3-oxocyclopentene-1-carboxylate (1S,2R,6S,7R,8S,10R,13R)-2,7,8-trihydroxy-6-(hydroxymethyl)-7,13-dimethyl-4,9-dioxatetracyclo[6.5.1.01,10.06,10]tetradecan-3-one Majusanic acid F [[Q105162049|(1S,2S,6S,7S,8S)-7-hydroxy-2,6-dimethyl-14-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4,11-dioxatetracyclo[6.3.3.01,8.02,6]tetradec-13-ene-5,10-dione]] Majusanic acid E (1S,4As,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylic acid
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Journal of Natural Products
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10.1021/NP400638R
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8
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Cloning of a second non-haem bromoperoxidase gene from Streptomyces aureofaciens ATCC 10762: sequence analysis, expression in Streptomyces lividans and enzyme purification
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Streptomyces globisporus Streptomyces albus Kitasatospora aureofaciens Streptomyces aureofaciens Streptomyces rimosus unspecified tetracycline (4S,6S,12aR)-7-chloro-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide tetracycline chlorotetracycline Streptomyces lividans
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Microbiology
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10.1099/00221287-140-3-509
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9
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Studies on cytotoxic constituents from the skin of the toad Bufo bufo gargarizans
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Common toad Asiatic toad Resibufogenin Telocinobufatoxin 5-[(1R,3S,5S,8R,9S,10S,13R,14S,17R)-1,3,5,14-tetrahydroxy-10,13-dimethyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pyran-2-one (2S)-2-[(7-{[(1R,2S,3aS,3bR,5aR,7S,9aS,9bS,11aR)-2-(acetyloxy)-3a-hydroxy-9a,11a-dimethyl-1-(6-oxopyran-3-yl)-tetradecahydrocyclopenta[a]phenanthren-7-yl]oxy}-1-hydroxy-7-oxoheptylidene)amino]-5-carbamimidamidopentanoic acid (2S)-2-[(4-{[(1R,2S,3aS,3bR,5aR,7S,9aS,9bS,11aR)-2-(acetyloxy)-3a-hydroxy-9a,11a-dimethyl-1-(6-oxopyran-3-yl)-tetradecahydrocyclopenta[a]phenanthren-7-yl]oxy}-1-hydroxy-4-oxobutylidene)amino]-5-carbamimidamidopentanoic acid Hellebrigenin [[Q104920639|(2S)-5-(diaminomethylideneamino)-2-[[8-[[(3S,5S,8R,9S,10S,13R,14S,17R)-10-formyl-5,14-dihydroxy-13-methyl-17-(6-oxopyran-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-8-oxooctanoyl]amino]pentanoic acid]] bufotalin [[Q105206900|(2S)-2-[[9-[[(1R,2S,4R,5R,6R,7R,10S,11R,14S,16S)-5-acetyloxy-16-hydroxy-7,11-dimethyl-6-(6-oxopyran-3-yl)-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadecan-14-yl]oxy]-9-oxononanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid]] (1R,2S,4R,5R,6R,7R,10S,11S,14S,16S)-5,14,16-trihydroxy-7-methyl-6-(6-oxopyran-3-yl)-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadecane-11-carbaldehyde [[Q105155589|(2S)-2-[[4-[[(1R,2S,4R,5R,6R,7R,10S,11S,14S,16R)-5-acetyloxy-7,11-dimethyl-6-(6-oxopyran-3-yl)-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadecan-14-yl]oxy]-4-oxobutanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid]] 5-[(3S,5R,8R,9S,10S,11S,13R,14S,17R)-3,11,14-trihydroxy-10,13-dimethyl-12-oxo-2,3,4,5,6,7,8,9,11,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pyran-2-one Telocinobufagin bufotalin [[Q82936986|5-(Diaminomethylideneamino)-2-[[8-[[14-hydroxy-10,13-dimethyl-17-(6-oxopyran-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]oxy]-8-oxooctanoyl]amino]pentanoic acid]] [[Q105292594|3beta-[4-Oxo-4-[[(S)-1-carboxy-4-guanidinobutyl]amino]butanoyloxy]-14-hydroxy-5beta-bufa-20,22-dienolide]] Bufalitoxin resibufogenin
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Journal of Asian Natural Products Research
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10.1080/10286020.2010.505187
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30
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Flavonoids in the poisonous plant Oxytropis falcata
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Oxytropis falcata 2-Propen-1-one, 1-(2-hydroxy-4-methoxyphenyl)-3-(4-hydroxyphenyl)- (3S)-7-hydroxy-3-[(4-hydroxyphenyl)methyl]-2,3-dihydrochromen-4-one pinostrobin 4-[(1R,2R)-2-hydroxy-1-[(3R)-7-hydroxy-3-(2-hydroxy-3,4-dimethoxyphenyl)-3,4-dihydro-2H-chromen-6-yl]-3-(4-hydroxyphenyl)propyl]benzene-1,3-diol Daidzein-4'-glucoside (3R)-3-(2,3-Dihydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol daidzein (-)-maackiain 5',7'-dihydroxy-4'-glucosyloxyisoflavone 7,4'-dihydroxy-3'-methoxyisoflavone (l)-Edunol 5-[(3R)-7-hydroxy-3,4-dihydro-2H-chromen-3-yl]-2,3-dimethoxycyclohexa-2,5-diene-1,4-dione (3R)-3-(6-methoxy-1,3-benzodioxol-5-yl)-3,4-dihydro-2H-chromen-7-ol Oxytropisoflavan B 4'-Methoxy-2'-hydroxy chalcone (6aR,11aR)-3,8-dihydroxy-9,10-dimethoxypterocarpan Isoformononetin (R)-Isomucronulatol Isoliquiritigenin 4'-methyl ether sakuranetin 2-hydroxy-4-methoxychalcone (3R)-mucronulatol liquiritigenin (S)-7-hydroxyflavanone Liquiritigenin 7-methylether 2',4'-dihydroxychalcone pseudobaptigenin 1-(2,4-dihydroxyphenyl)-3-phenylprop-2-en-1-one Oxytropisoflavan A (6aR,11aR)-9-methoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromene-3,10-diol calycosin (2S)-7-Methoxyflavanone 2'-hydroxybiochanin A 4-[(2R)-2-hydroxy-3-(4-hydroxyphenyl)propyl]benzene-1,3-diol 1-(2,4-dihydroxyphenyl)-3-phenylpropan-1-one formononetin Corylifolinin;Isobacachalcone
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Journal of Natural Products
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10.1021/NP100339U
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37
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Triterpenoids from Calophyllum inophyllum and their growth inhibitory effects on human leukemia HL-60 cells
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Alexandrian laurel CID 12082783 oleanolic acid 3-Oxofriedelane-28-oic acid friedelin 28-Oxo-D:A-friedooleanan-3-one epi-Friedelanol Canophyllol
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Fitoterapia
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10.1016/J.FITOTE.2010.02.005
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7
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Sesquiterpenoids and diterpenoids from Chloranthus anhuiensis
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5,8-dihydroxy-3,5,8a-trimethyl-6,7,8,9-tetrahydro-4aH-benzo[f][1]benzofuran-4-one 5-(4,5-dihydroxy-3-methylpent-2-enyl)-1,4a-dimethyl-6-methylidene-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylic acid 8,9a-dihydroxy-3,4a,5-trimethyl-7,8,8a,9-tetrahydro-4H-benzo[f][1]benzofuran-2-one 1,4a-dimethyl-6-methylidene-5-(3-methyl-5-oxopent-2-enyl)-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylic acid 5-(hydroxymethyl)-1,4a-dimethyl-6-methylidene-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylic acid 2-hydroxy-5-(3-hydroxy-3-methylpent-4-enyl)-1,4a-dimethyl-6-methylidene-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylic acid 2-hydroxy-4-[(2-hydroxy-2-methyl-5-prop-1-en-2-ylcyclopentyl)methyl]-3-methyl-2H-furan-5-one 5-(carboxymethyl)-1,4a-dimethyl-6-methylidene-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylic acid 3,5,8a-Trimethyl-2,4,4a,5,6,7,9,9a-octahydrobenzo[f][1]benzofuran-8-one Lassiosiphol CID 15559751 5-(2,5-dihydroxy-3-methylpent-3-enyl)-1,4a-dimethyl-6-methylidene-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylic acid 3-ethenyl-3,4a,7,7,10a-pentamethyl-2,5,6,6a,8,9,10,10b-octahydro-1H-benzo[f]chromene-5,8-diol 5-(5-hydroxy-3-methyl-2-oxopent-3-enyl)-1,4a-dimethyl-6-methylidene-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylic acid 6,9a-Dihydroxy-3,8a-dimethyl-5-methylidene-4,4a,6,7,8,9-hexahydrobenzo[f][1]benzofuran-2-one Chloranthus spicatus Oryctanthus spicatus
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Chemistry and Biodiversity
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10.1002/CBDV.200800300
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30
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