The role of apoptosis in the development and function of T lymphocytes (Q36295655)

13 August 2017

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title

The role of apoptosis in the development and function of T lymphocytes (English)

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13 August 2017

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Nu Zhang

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Ivan Dzhagalov

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Ivan Dzhagalov

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author name string

Heather Hartig

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13 August 2017

David Draper

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13 August 2017

You Wen He

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13 August 2017

1 October 2005

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13 August 2017

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13 August 2017

15

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13 August 2017

10

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13 August 2017

749-769

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https://scigraph.springernature.com/pub.10.1038/sj.cr.7290345

13 August 2017

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cites work

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Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18.

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Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?

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BCL-2 family members and the mitochondria in apoptosis

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BCL-2 family: regulators of cell death

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Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

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Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia

21 January 2018

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Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice

21 January 2018

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Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice

21 January 2018

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bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

21 January 2018

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An additional form of rat Bcl-x, Bcl-xbeta, generated by an unspliced RNA, promotes apoptosis in promyeloid cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

A novel Bcl-x isoform connected to the T cell receptor regulates apoptosis in T cells

21 January 2018

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bcl-xL is critical for dendritic cell survival in vivo.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

A Bcl-2-dependent molecular timer regulates the lifespan and immunogenicity of dendritic cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Bcl-XL displays restricted distribution during T cell development and inhibits multiple forms of apoptosis but not clonal deletion in transgenic mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Bclx regulates the survival of double-positive thymocytes

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Requirement for RORgamma in thymocyte survival and lymphoid organ development

21 January 2018

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Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L).

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

A1 functions at the mitochondria to delay endothelial apoptosis in response to tumor necrosis factor

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Functional dissection of Bfl-1, a Bcl-2 homolog: anti-apoptosis, oncogene-cooperation and cell proliferation activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Induction of apoptosis by the Bcl-2 homologue Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

A splicing variant of the Bcl-2 member Bok with a truncated BH3 domain induces apoptosis but does not dimerize with antiapoptotic Bcl-2 proteins in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Proapoptotic BAX and BAK control multiple initiator caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

X-linked IAP is a direct inhibitor of cell-death proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Structural basis of caspase-7 inhibition by XIAP

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Structural basis for the inhibition of caspase-3 by XIAP

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

IAP proteins: blocking the road to death's door

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Structural and biochemical basis of apoptotic activation by Smac/DIABLO

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Endonuclease G is an apoptotic DNase when released from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Mitochondrial endonuclease G is important for apoptosis in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Molecular characterization of mitochondrial apoptosis-inducing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

BH3-Only proteins-essential initiators of apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

BID: a novel BH3 domain-only death agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

PUMA induces the rapid apoptosis of colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

PUMA mediates the apoptotic response to p53 in colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Proapoptotic BH3-only Bcl-2 family member Bik/Blk/Nbk is expressed in hemopoietic and endothelial cells but is redundant for their programmed death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

The TNF and TNF receptor superfamilies: integrating mammalian biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

The signaling adaptors and pathways activated by TNF superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

The death domain: a module shared by proteins with diverse cellular functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Identification and functional characterization of DR6, a novel death domain-containing TNF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Mature T lymphocyte apoptosis--immune regulation in a dynamic and unpredictable antigenic environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Fas and Fas ligand: lpr and gld mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Autoproteolytic activation of pro-caspases by oligomerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Inhibition of death receptor signals by cellular FLIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Casper is a FADD- and caspase-related inducer of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

CASH, a novel caspase homologue with death effector domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Regulation of lymphocyte proliferation and death by FLIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

NF-kappaB signals induce the expression of c-FLIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Induction of cIAP-2 in Human Colon Cancer Cells through PKCδ/NF-κB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

The TNF receptor 1: a split personality complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Fas-associated Death Domain Protein and Caspase-8 Are Not Recruited to the Tumor Necrosis Factor Receptor 1 Signaling Complex during Tumor Necrosis Factor-induced Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Positive and negative selection of T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Control points in early T-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Gated Importation of Prothymocytes by Adult Mouse Thymus Is Coordinated with Their Periodic Mobilization from Bone Marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

The importation of hematogenous precursors by the thymus is a gated phenomenon in normal adult mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

The ins and outs of CCR7 in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Thymic T cell development and progenitor localization depend on CCR7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

FADD/MORT1 regulates the pre-TCR checkpoint and can function as a tumour suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Rapid induction of medullary thymocyte phenotypic maturation and egress inhibition by nanomolar sphingosine 1-phosphate receptor agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

CCR7 signals are essential for cortex-medulla migration of developing thymocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

An essential role for c-FLIP in the efficient development of mature T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Negative selection--clearing out the bad apples from the T-cell repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

The timing of TCR alpha expression critically influences T cell development and selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Negative selection in the thymus includes semimature T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Developmental status of CD4-CD8+ and CD4+CD8- thymocytes with medium expression of CD3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Self-representation in the thymus: an extended view

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

A role for Fas in negative selection of thymocytes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Normal thymocyte negative selection in TRAIL-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

TRAIL-R as a negative regulator of innate immune cell responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

DR3 regulates negative selection during thymocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Negative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

The apoptotic protease-activating factor 1-mediated pathway of apoptosis is dispensable for negative selection of thymocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Blocked negative selection of developing T cells in mice expressing the baculovirus p35 caspase inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Caspase enzyme activity is not essential for apoptosis during thymocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Homeostasis of alpha beta TCR+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Population biology of lymphocytes: the flight for survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Interleukin-7: master regulator of peripheral T-cell homeostasis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

IL-7 is critical for homeostatic proliferation and survival of naive T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hosts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

CD8(+) T-cell homeostasis after infection: setting the 'curve'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Effector and memory T-cell differentiation: implications for vaccine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Help for cytotoxic-T-cell responses is mediated by CD40 signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

CD4+ T cells are required for the maintenance, not programming, of memory CD8+ T cells after acute infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Helping the CD8(+) T-cell response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Early programming of T cell populations responding to bacterial infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Cutting edge: antigen-independent CD8 T cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Feedback regulation of pathogen-specific T cell priming.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Regulation of antigen-specific CD8+ T cell homeostasis by perforin and interferon-gamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

What messenger RNA capping tells us about eukaryotic evolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Resistance of short term activated T cells to CD95-mediated apoptosis correlates with de novo protein synthesis of c-FLIPshort

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

The contraction phase of virus-specific CD8+ T cells is unaffected by a pan-caspase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Regulation of expression of Bcl-2 protein family member Bim by T cell receptor triggering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Loss of Bim increases T cell production and function in interleukin 7 receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Dynamic regulation of IFN-gamma signaling in antigen-specific CD8+ T cells responding to infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Adaptive immunity and enhanced CD8+ T cell response to Listeria monocytogenes in the absence of perforin and IFN-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

CD8+ T cell contraction is controlled by early inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

CD8alphaalpha-mediated survival and differentiation of CD8 memory T cell precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

T cell responses modulated through interaction between CD8alphaalpha and the nonclassical MHC class I molecule, TL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Cutting edge: a single MHC class Ia is sufficient for CD8 memory T cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Persistence of memory CD8 T cells in MHC class I-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Cutting edge: requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORgammat: impact on thymocyte development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Death and Baxes: mechanisms of lymphotrophic cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Jak3 selectively regulates Bax and Bcl-2 expression to promote T-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

A point mutation in CD28 distinguishes proliferative signals from survival signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Cutting edge: distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Differential T cell costimulatory requirements in CD28-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

CD28(-/-) mice show defects in cellular and humoral immunity but are able to control infection with murine gammaherpesvirus 68.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

B7 costimulation is critical for antibody class switching and CD8(+) cytotoxic T-lymphocyte generation in the host response to vesicular stomatitis virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Role of CD28 for the generation and expansion of antigen-specific CD8(+) T lymphocytes during infection with Listeria monocytogenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

CD27 Promotes Survival of Activated T Cells and Complements CD28 in Generation and Establishment of the Effector T Cell Pool

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

The costimulation-regulated duration of PKB activation controls T cell longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Co-stimulatory members of the TNFR family: keys to effective T-cell immunity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

CD4(+)CD3(-) accessory cells costimulate primed CD4 T cells through OX40 and CD30 at sites where T cells collaborate with B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

OX40-deficient mice are defective in Th cell proliferation but are competent in generating B cell and CTL Responses after virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

The OX40 costimulatory receptor determines the development of CD4 memory by regulating primary clonal expansion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

4-1BB promotes the survival of CD8+ T lymphocytes by increasing expression of Bcl-xL and Bfl-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Costimulatory ligand 4-1BBL (CD137L) as an efficient adjuvant for human antiviral cytotoxic T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Immune responses in 4-1BB (CD137)-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Evidence that human CD8+CD45RA+CD27- cells are induced by antigen and evolve through extensive rounds of division.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Lineage relationship and protective immunity of memory CD8 T cell subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

CD27 is required for generation and long-term maintenance of T cell immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

The antiapoptotic protein Bcl-xL is dispensable for the development of effector and memory T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

The CD40-Inducible Bcl-2 Family Member A1 Protects B Cells from Antigen Receptor-Mediated Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Suppression of IL7Rα Transcription by IL-7 and Other Prosurvival Cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Dynamic regulation of IL-7 receptor expression is required for normal thymopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

p53 triggers apoptosis in oncogene-expressing fibroblasts by the induction of Noxa and mitochondrial Bax translocation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

A JNK-Dependent Pathway Is Required for TNFα-Induced Apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

Selecting and maintaining a diverse T-cell repertoire

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

Spontaneous Thymocyte Apoptosis Is Regulated by a Mitochondrion-Mediated Signaling Pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

The thymus and negative selection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

Defective thymocyte apoptosis and accelerated autoimmune diseases in TRAIL-/- mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

TRAIL and thymocyte apoptosis: not so deadly?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

Designing and maintaining the mature TCR repertoire: the continuum of self-peptide:self-MHC complex recognition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

MHC Class II Molecules Are Not Required for Survival of Newly Generated CD4+ T Cells, but Affect Their Long-Term Life Span

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

The CD8 response on autopilot.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

Viral infection results in massive CD8+ T cell expansion and mortality in vaccinated perforin-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

Programmed contraction of CD8(+) T cells after infection.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

Immune down-regulation and peripheral deletion of CD8 T cells does not require TNF receptor-ligand interactions nor CD95 (Fas, APO-1)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

Overexpression of IL-15 in vivo increases antigen-driven memory CD8+ T cells following a microbe exposure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

CD28 and inducible costimulatory protein Src homology 2 binding domains show distinct regulation of phosphatidylinositol 3-kinase, Bcl-xL, and IL-2 expression in primary human CD4 T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

4-1BB co-stimulation enhances human CD8(+) T cell priming by augmenting the proliferation and survival of effector CD8(+) T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290345

7 January 2021

Identifiers

DOI

10.1038/SJ.CR.7290345

1 reference

Dimensions Publication ID

13 August 2017

0 references

1 reference