Cell biology. Metabolic control of cell death (Q28397089)

on focus list of Wikimedia project

Europe PubMed Central

title

Cell biology. Metabolic control of cell death (English)

0 references

0 references

2

Lorenzo Galluzzi

0 references

Guido Kroemer

series ordinal

3

object named as

Guido Kroemer

0 references

Douglas R. Green

object named as

Douglas R Green

series ordinal

1

0 references

language of work or name

English

0 references

publication date

19 September 2014

0 references

published in

Science

0 references

volume

345

0 references

page(s)

1250256

0 references

issue

6203

0 references

ScienceSource

0 references

cites work

To be or not to be? How selective autophagy and cell death govern cell fate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Posttranscriptional control of T cell effector function by aerobic glycolysis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Dimers of mitochondrial ATP synthase form the permeability transition pore

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

p53 opens the mitochondrial permeability transition pore to trigger necrosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Subcellular dynamics of multifunctional protein regulation: mechanisms of GAPDH intracellular translocation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

RIPK-dependent necrosis and its regulation by caspases: a mystery in five acts

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Mitochondria and the autophagy-inflammation-cell death axis in organismal aging

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

A role for mitochondria in NLRP3 inflammasome activation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

An overview of sphingolipid metabolism: from synthesis to breakdown

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Membrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerization

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

19 March 2017

Life with or without AIF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Regulation of autophagy by cytoplasmic p53

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

AMPK phosphorylation of raptor mediates a metabolic checkpoint

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

No death without life: vital functions of apoptotic effectors

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

A genome-wide RNAi screen reveals multiple regulators of caspase activation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

TIGAR, a p53-inducible regulator of glycolysis and apoptosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

p53 regulates mitochondrial respiration

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Gout-associated uric acid crystals activate the NALP3 inflammasome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Targeting HIF-1 for cancer therapy

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Checkpoints: controls that ensure the order of cell cycle events

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Bax regulates primary necrosis through mitochondrial dynamics

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Intracellular localization of the BCL-2 family member BOK and functional implications

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos)

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Role of Bax and Bak in mitochondrial morphogenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Growth factor regulation of autophagy and cell survival in the absence of apoptosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

19 March 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Non-canonical inflammasome activation targets caspase-11

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

The human apoptosis-inducing protein AMID is an oxidoreductase with a modified flavin cofactor and DNA binding activity

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

A ubiquitin-like system mediates protein lipidation

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Dual role of proapoptotic BAD in insulin secretion and beta cell survival

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Calpain-mediated cleavage of Beclin-1 and autophagy deregulation following retinal ischemic injury in vivo

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis.

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

New insights into the function and regulation of mitochondrial fission

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated manner

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

OPA1 requires mitofusin 1 to promote mitochondrial fusion

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphology

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

The proapoptotic function of Noxa in human leukemia cells is regulated by the kinase Cdk5 and by glucose

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Modulation of F0F1-ATP synthase activity by cyclophilin D regulates matrix adenine nucleotide levels

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Cyclophilin D modulates mitochondrial F0F1-ATP synthase by interacting with the lateral stalk of the complex

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

AMP-Activated Protein Kinase in Metabolic Control and Insulin Signaling

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Sirtuin 1 and sirtuin 3: physiological modulators of metabolism

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

The NAD-dependent deacetylase SIRT2 is required for programmed necrosis

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Functional expression of human adenine nucleotide translocase 4 in Saccharomyces cerevisiae

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Unspecific permeation and specific exchange of adenine nucleotides in liver mitochondria

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Two distinct genes for ADP/ATP translocase are expressed at the mRNA level in adult human liver

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Peripheral-type benzodiazepine receptor: structure and function of a cholesterol-binding protein in steroid and bile acid biosynthesis

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Ischemic nitric oxide and poly (ADP-ribose) polymerase-1 in cerebral ischemia: male toxicity, female protection

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Iron-sulfur protein maturation in human cells: evidence for a function of frataxin

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

A pool of extramitochondrial frataxin that promotes cell survival

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Ganglioside-induced differentiation-associated protein-1 is mutant in Charcot-Marie-Tooth disease type 4A/8q21

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Interplay of LRRK2 with chaperone-mediated autophagy

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Defective endocytic trafficking of NPC1 and NPC2 underlying infantile Niemann-Pick type C disease

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Mutations in NPC1 highlight a conserved NPC1-specific cysteine-rich domain

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Niemann-Pick C variant detection by altered sphingolipid trafficking and correlation with mutations within a specific domain of NPC1.

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

NPC1 gene mutations in Japanese patients with Niemann-Pick disease type C

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Niemann-Pick C1 protein: obligatory roles for N-terminal domains and lysosomal targeting in cholesterol mobilization

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Correction: Uncoupling of Longevity and Telomere Length in C. elegans

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Identification of HE1 as the second gene of Niemann-Pick C disease

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Spectrum, frequency and penetrance of OPA1 mutations in dominant optic atrophy

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Mutation spectrum and splicing variants in the OPA1 gene

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

A novel mutation in the OPA1 gene in a Japanese patient with optic atrophy

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

A major marker for normal tension glaucoma: association with polymorphisms in the OPA1 gene

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Parkin promotes degradation of the mitochondrial pro-apoptotic ARTS protein

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Park7, a novel locus for autosomal recessive early-onset parkinsonism, on chromosome 1p36.

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Bioenergetic consequences of PINK1 mutations in Parkinson disease

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Oxidative stress-induced apoptosis in neurons correlates with mitochondrial DNA base excision repair pathway imbalance

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Mutations in the novel mitochondrial protein REEP1 cause hereditary spastic paraplegia type 31

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Hereditary spastic paraplegia proteins REEP1, spastin, and atlastin-1 coordinate microtubule interactions with the tubular ER network

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Niemann-Pick disease: a frequent missense mutation in the acid sphingomyelinase gene of Ashkenazi Jewish type A and B patients

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Identification of a missense mutation (S436R) in the acid sphingomyelinase gene from a Japanese patient with type B Niemann-Pick disease

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Spastic paraplegia and OXPHOS impairment caused by mutations in paraplegin, a nuclear-encoded mitochondrial metalloprotease

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

A new locus for autosomal recessive hereditary spastic paraplegia maps to chromosome 16q24.3

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

A novel X-linked gene, G4.5. is responsible for Barth syndrome

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

The enigmatic role of tafazzin in cardiolipin metabolism

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

UBE2A, which encodes a ubiquitin-conjugating enzyme, is mutated in a novel X-linked mental retardation syndrome

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Exome sequencing reveals VCP mutations as a cause of familial ALS

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1250256

Autophagy and the integrated stress response

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Mitochondrial membrane permeabilization in cell death

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Hypoxia--a key regulatory factor in tumour growth

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

The BCL-2 protein family: opposing activities that mediate cell death

7 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250256

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

ATP-citrate lyase links cellular metabolism to histone acetylation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Autophagic cell death: the story of a misnomer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

ER tubules mark sites of mitochondrial division

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

The LKB1-AMPK pathway: metabolism and growth control in tumour suppression

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

ER stress triggers apoptosis by activating BH3-only protein Bim

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Mitochondria, oxidative stress and cell death

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis

7 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250256

Molecular mechanisms of necroptosis: an ordered cellular explosion

22 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250256

BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

22 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250256

The glamour and gloom of glycogen synthase kinase-3

22 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250256

A central role for JNK in obesity and insulin resistance

22 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250256

Disruption of fusion results in mitochondrial heterogeneity and dysfunction

22 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250256

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

22 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250256

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

22 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250256

Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A

22 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250256

Association between early-onset Parkinson's disease and mutations in the parkin gene

22 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250256

Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein

22 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250256

Autophagy variation within a cell population determines cell fate through selective degradation of Fap-1.

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

The E3 ubiquitin ligases β-TrCP and FBXW7 cooperatively mediates GSK3-dependent Mcl-1 degradation induced by the Akt inhibitor API-1, resulting in apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

CDIP1-BAP31 complex transduces apoptotic signals from endoplasmic reticulum to mitochondria under endoplasmic reticulum stress

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Metabolic activation of CaMKII by coenzyme A.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Mechanisms of mitochondrial fission and fusion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Dysregulated mTORC1 renders cells critically dependent on desaturated lipids for survival under tumor-like stress

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Extracellular adenosine sensing-a metabolic cell death priming mechanism downstream of p53.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Non-cell-autonomous tumor suppression by p53.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Mitochondrial dynamics in the regulation of nutrient utilization and energy expenditure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Metabolomic profiling reveals a role for caspase-2 in lipoapoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

The B55α subunit of PP2A drives a p53-dependent metabolic adaptation to glutamine deprivation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Control of nutrient stress-induced metabolic reprogramming by PKCζ in tumorigenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Metabolism of inflammation limited by AMPK and pseudo-starvation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Metabolic checkpoints in activated T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Drosophila larvae lacking the bcl-2 gene, buffy, are sensitive to nutrient stress, maintain increased basal target of rapamycin (Tor) signaling and exhibit characteristics of altered basal energy metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

The impact of the unfolded protein response on human disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

BCL2 suppresses PARP1 function and nonapoptotic cell death.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Anti-ceramide antibody prevents the radiation gastrointestinal syndrome in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Inflammasomes in carcinogenesis and anticancer immune responses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Molecular basis of the interaction between proapoptotic truncated BID (tBID) protein and mitochondrial carrier homologue 2 (MTCH2) protein: key players in mitochondrial death pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

A unified model of mammalian BCL-2 protein family interactions at the mitochondria.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

AMPK and mTOR in cellular energy homeostasis and drug targets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

A biotin switch-based proteomics approach identifies 14-3-3ζ as a target of Sirt1 in the metabolic regulation of caspase-2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Mitochondrial ceramide-rich macrodomains functionalize Bax upon irradiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Mechanisms of lipotoxicity in NAFLD and clinical implications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

The soluble form of Bax regulates mitochondrial fusion via MFN2 homotypic complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Glycogen synthase kinase-3 (GSK-3) inhibition attenuates hepatocyte lipoapoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Ribosome biogenesis surveillance: probing the ribosomal protein-Mdm2-p53 pathway.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Resistance to caspase-independent cell death requires persistence of intact mitochondria

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Glucose deprivation induces an atypical form of apoptosis mediated by caspase-8 in Bax-, Bak-deficient cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

N-terminal acetylation of cellular proteins creates specific degradation signals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

AMPK-independent down-regulation of cFLIP and sensitization to TRAIL-induced apoptosis by AMPK activators

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Caspase-independent mitochondrial cell death results from loss of respiration, not cytotoxic protein release.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Novel roles for GAPDH in cell death and carcinogenesis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

The GAIT system: a gatekeeper of inflammatory gene expression.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Metabolic control of oocyte apoptosis mediated by 14-3-3zeta-regulated dephosphorylation of caspase-2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Cytoplasmic functions of the tumour suppressor p53.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

BCL-xL is a target gene regulated by hypoxia-inducible factor-1{alpha}.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Lysosomal membrane permeabilization in cell death

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Caspase-2 functions upstream of mitochondria in endoplasmic reticulum stress-induced apoptosis by bortezomib in human myeloma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Bax- or Bak-induced mitochondrial fission can be uncoupled from cytochrome C release

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Bcl-2 protein family members: versatile regulators of calcium signaling in cell survival and apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Mitochondrial bioenergetics and structural network organization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Autophagic programmed cell death by selective catalase degradation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Role for CED-9 and Egl-1 as regulators of mitochondrial fission and fusion dynamics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Caspase-12 and caspase-4 are not required for caspase-dependent endoplasmic reticulum stress-induced apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Hypoxia-inducible factor-1-dependent overexpression of myeloid cell factor-1 protects hypoxic cells against tert-butyl hydroperoxide-induced apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Alkylating DNA damage stimulates a regulated form of necrotic cell death

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Inhibition of glucose metabolism sensitizes tumor cells to death receptor-triggered apoptosis through enhancement of death-inducing signaling complex formation and apical procaspase-8 processing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

The pantheon of the fallen: why are there so many forms of cell death?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Autophagy and apoptosis: what is the connection?

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Calpain activation is not required for AIF translocation in PARP-1-dependent cell death (parthanatos).

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Metabolic targets for cancer therapy

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Caloric restriction modulates Mcl-1 expression and sensitizes lymphomas to BH3 mimetic in mice.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Cardioprotection by the TSPO ligand 4'-chlorodiazepam is associated with inhibition of mitochondrial accumulation of cholesterol at reperfusion

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Bax and Bcl-xL exert their regulation on different sites of the ceramide channel.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Mitochondrial ATP synthasome: three-dimensional structure by electron microscopy of the ATP synthase in complex formation with carriers for Pi and ADP/ATP.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4219413

Activation of glycogen synthase kinase 3beta disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy-induced cytotoxicity

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25237106

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mitochondrial apoptosis without VDAC

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25237106

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Elevated NADPH oxidase activity contributes to oxidative stress and cell death in Huntington's disease

1 reference

12 January 2024

https://opencitations.net/index/api/v1/citations/10.1093/HMG/DDS516

Identifiers

DOI

10.1126/SCIENCE.1250256

1 reference

81767

81767

1 reference

1 reference

1 reference