Lysosomal cathepsins and their regulation in aging and neurodegeneration (Q26749121)

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The major histocompatibility complex and autism spectrum disorder.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Update of the mutation spectrum and clinical correlations of over 360 mutations in eight genes that underlie the neuronal ceroid lipofuscinoses

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Two crystal structures for cathepsin D: the lysosomal targeting signal and active site

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Increase in cathepsin D activity in rat brain in aging

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cathepsin B but not cathepsins L or S contributes to the pathogenesis of Unverricht-Lundborg progressive myoclonus epilepsy (EPM1)

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Fast profiling of protease specificity reveals similar substrate specificities for cathepsins K, L and S.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

High-affinity binding of two molecules of cysteine proteinases to low-molecular-weight kininogen.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Procathepsin L degrades extracellular matrix proteins in the presence of glycosaminoglycans in vitro

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Inhibition mechanism of cathepsin L-specific inhibitors based on the crystal structure of papain-CLIK148 complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Immunohistochemical localization of kininogen in rat spinal cord and brain.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The structures of native phosphorylated chicken cystatin and of a recombinant unphosphorylated variant in solution

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Conformational Variability of Chicken Cystatin

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The three-dimensional solution structure of human stefin A

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Crystal structure of the wild-type human procathepsin B at 2.5 A resolution reveals the native active site of a papain-like cysteine protease zymogen

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Ultrastructural observations on neuronal lipofuscin (age pigment) and dense bodies induced by a proteinase inhibitor, leupeptin, in rat hippocampus.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Developmental changes in the breakdown of brain tubulin by cerebral cathepsin D.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Rat neural tissue cathepsin D: ultrastructural immunocytochemistry.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cortical cathepsin D activity and immunolocalization in Alzheimer disease, critical coronary artery disease, and aging

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Involvement of cathepsin B in the motor neuron degeneration of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Novel mutation and the first prenatal screening of cathepsin D deficiency (CLN10).

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Regulation of apoptosis-associated lysosomal membrane permeabilization

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cystatin B and SOD1: protein–protein interaction and possible relation to neurodegeneration.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Spinal cord mRNA profile in patients with ALS: comparison with transgenic mice expressing the human SOD-1 mutant.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Surface activation of pro-cathepsin L

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Inactivation of human cystatin C and kininogen by human cathepsin D

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Novel epoxysuccinyl peptides. Selective inhibitors of cathepsin B, in vitro

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Novel epoxysuccinyl peptides. A selective inhibitor of cathepsin B, in vivo

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The cystatins: Protein inhibitors of cysteine proteinases

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Purification of the complex of cathepsin L and the MHC class II-associated invariant chain fragment from human kidney

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Kinetics of inhibition of bovine cathepsin S by bovine stefin B

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

High-molecular-weight kininogen binds two molecules of cysteine proteinases with different rate constants

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Age-dependent change in activities of lysosomal enzymes in rat brain

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Lysosome instability in aged rat brain

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Antigenic expression of cathepsin B in aged human brain.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The neuronal ceroid-lipofuscinoses: a historical introduction.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Human pathology in NCL.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cell biology and function of neuronal ceroid lipofuscinosis-related proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cell biology of the NCL proteins: What they do and don't do.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cysteine cathepsins and extracellular matrix degradation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cystatin B and its EPM1 mutants are polymeric and aggregate prone in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

N-terminally truncated forms of human cathepsin F accumulate in aggresome-like inclusions

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Gain in toxic function of stefin B EPM1 mutants aggregates: correlation between cell death, aggregate number/size and oxidative stress.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Lysosomes and lysosomal cathepsins in cell death

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cysteine cathepsins: from structure, function and regulation to new frontiers

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Microglia-aging: roles of microglial lysosome- and mitochondria-derived reactive oxygen species in brain aging.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

A heparin binding motif on the pro-domain of human procathepsin L mediates zymogen destabilization and activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cathepsin D: a cellular roadmap

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cysteine cathepsins: cellular roadmap to different functions

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Pathophysiological functions of cathepsin D: Targeting its catalytic activity versus its protein binding activity?

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Autoactivation of prolegumain is accelerated by glycosaminoglycans

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Neuroectoderm-specific deletion of cathepsin D in mice models human inherited neuronal ceroid lipofuscinosis type 10.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Upregulation of cathepsin S in the aging and pathological nervous system of mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Combating apoptosis and multidrug resistant cancers by targeting lysosomes.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The hallmarks of aging

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Unverricht-Lundborg disease: homozygosity for a new splicing mutation in the cystatin B gene

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Differential expression of cathepsin X in aging and pathological central nervous system of mice.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Recombinant human procathepsin S is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Protease signalling in cell death: caspases versus cysteine cathepsins.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Essential role of proline isomerization in stefin B tetramer formation

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Identification and characterization of an increased glycoprotein in aging: age-associated translocation of cathepsin D.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Lysosomal membrane permeabilization in cell death: concepts and challenges.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Lysosomal proteases are involved in generation of N-terminal huntingtin fragments

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Lysosomal enzyme cathepsin B enhances the aggregate forming activity of exogenous α-synuclein fibrils

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Differential pathways for interleukin-1β production activated by chromogranin A and amyloid β in microglia.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cystatin C-cathepsin B axis regulates amyloid beta levels and associated neuronal deficits in an animal model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Matrix metalloproteinases are modifiers of huntingtin proteolysis and toxicity in Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Altered distribution and levels of cathepsinD and cystatins in amyotrophic lateral sclerosis transgenic mice: possible roles in motor neuron survival.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Carboxypeptidases cathepsins X and B display distinct protein profile in human cells and tissues

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

A mutation in the cathepsin D gene (CTSD) in American Bulldogs with neuronal ceroid lipofuscinosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Characterization of a rare Unverricht-Lundborg disease mutation

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease).

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

On the size of the active site in proteases. I. Papain

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The crystal structure of human cathepsin L complexed with E-64

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Structure based development of novel specific inhibitors for cathepsin L and cathepsin S in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Autocatalytic processing of recombinant human procathepsin B is a bimolecular process.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The crystal structure of human cathepsin F and its implications for the development of novel immunomodulators

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Neuronal ceroid lipofuscinoses: classification and diagnosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

6. Cathepsin K inhibitors: their potential as anti-osteoporosis agents

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cell death: critical control points

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

1 reference

7 January 2021

Lysosomal cysteine proteases: more than scavengers

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Regionally selective changes in brain lysosomes occur in the transition from young adulthood to middle age in rats

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

When lysosomes get old.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Crystal structure of cathepsin X: a flip-flop of the ring of His23 allows carboxy-monopeptidase and carboxy-dipeptidase activity of the protease

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Crystal structure of porcine cathepsin H determined at 2.1 A resolution: location of the mini-chain C-terminal carboxyl group defines cathepsin H aminopeptidase function

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Kinetics of the pH-induced inactivation of human cathepsin L

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Crystal structure of human cathepsin V

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Potent slow-binding inhibition of cathepsin B by its propeptide

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Human recombinant pro-dipeptidyl peptidase I (cathepsin C) can be activated by cathepsins L and S but not by autocatalytic processing

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Human cathepsin B is a metastable enzyme stabilized by specific ionic interactions associated with the active site

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The serpin SQN-5 is a dual mechanistic-class inhibitor of serine and cysteine proteinases

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Hurpin is a selective inhibitor of lysosomal cathepsin L and protects keratinocytes from ultraviolet-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The novel bovine serpin endopin 2C demonstrates selective inhibition of the cysteine protease cathepsin L compared to the serine protease elastase, in cross-class inhibition.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cathepsin D is the main lysosomal enzyme involved in the degradation of alpha-synuclein and generation of its carboxy-terminally truncated species

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cross-class inhibition of the cysteine proteinases cathepsins K, L, and S by the serpin squamous cell carcinoma antigen 1: a kinetic analysis

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Human cathepsin X: A cysteine protease with unique carboxypeptidase activity

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Proteomic identification of protease cleavage sites characterizes prime and non-prime specificity of cysteine cathepsins B, L, and S.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The endosomal-lysosomal system of neurons in Alzheimer's disease pathogenesis: a review

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Autophagy: many paths to the same end.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Progressive ataxia, myoclonic epilepsy and cerebellar apoptosis in cystatin B-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Dodecamer repeat expansion in cystatin B gene in progressive myoclonus epilepsy.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cystatin C protects neuronal cells against mutant copper-zinc superoxide dismutase-mediated toxicity

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Haploinsufficiency of cathepsin D leads to lysosomal dysfunction and promotes cell-to-cell transmission of α-synuclein aggregates

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Protease signalling: the cutting edge

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The roles of intracellular protein-degradation pathways in neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Autophagy fights disease through cellular self-digestion

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The lysosome turns fifty

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cystatin C inhibits amyloid-beta deposition in Alzheimer's disease mouse models

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The role of autophagy in neurodegenerative disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cysteine cathepsin proteases: regulators of cancer progression and therapeutic response

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Targeting proteases: successes, failures and future prospects

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Alzheimer disease therapy--moving from amyloid-β to tau.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Tau and neurodegenerative disease: the story so far.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Amyotrophic lateral sclerosis: mechanisms and therapeutics in the epigenomic era.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Crystal structure of human cathepsin K complexed with a potent inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Histone H3 tail clipping regulates gene expression

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Lysosomal membrane permeabilization in cell death

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Stefin B deficiency reduces tumor growth via sensitization of tumor cells to oxidative stress in a breast cancer model.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Apoptosis caused by cathepsins does not require Bid signaling in an in vivo model of progressive myoclonus epilepsy (EPM1).

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cystatin B: mutation detection, alternative splicing and expression in progressive myclonus epilepsy of Unverricht-Lundborg type (EPM1) patients

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin S

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Purified recombinant human prosaposin forms oligomers that bind procathepsin D and affect its autoactivation

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cathepsin S from bovine spleen. Purification, distribution, intracellular localization and action on proteins.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Papain-like lysosomal cysteine proteases and their inhibitors: drug discovery targets?

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

1 reference

7 January 2021

Human proteoglycan testican‐1 inhibits the lysosomal cysteine protease cathepsin L

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Acidic pH as a physiological regulator of human cathepsin L activity.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Potency and selectivity of inhibition of cathepsin K, L and S by their respective propeptides

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cytosolic proteolysis of tau by cathepsin D in hippocampus following suppression of cathepsins B and L.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Increased expression of cathepsins E and D in neurons of the aged rat brain and their colocalization with lipofuscin and carboxy-terminal fragments of Alzheimer amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

1 reference

7 January 2021

Neuronal loss and brain atrophy in mice lacking cathepsins B and L

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cysteine cathepsins are essential in lysosomal degradation of α-synuclein.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Amyloid fibrils in hereditary cerebral hemorrhage with amyloidosis of Icelandic type is a variant of gamma-trace basic protein (cystatin C)

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Enzymatically active lysosomal proteases are associated with amyloid deposits in Alzheimer brain

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Increased body temperature accelerates aggregation of the Leu-68-->Gln mutant cystatin C, the amyloid-forming protein in hereditary cystatin C amyloid angiopathy.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Proteolytic enzymes, past and future

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Amyloidogenic processing of human amyloid precursor protein in hippocampal neurons devoid of cathepsin D.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

pH-induced conformational transitions of the propeptide of human cathepsin L. A role for a molten globule state in zymogen activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

pH-induced Conformational Transitions of the Propeptide of Human Cathepsin L

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Autocatalytic processing of recombinant human procathepsin L. Contribution of both intermolecular and unimolecular events in the processing of procathepsin L in vitro

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Inhibition of mammalian legumain by some cystatins is due to a novel second reactive site

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cathepsin B activity regulation. Heparin-like glycosaminogylcans protect human cathepsin B from alkaline pH-induced inactivation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Identification of internal autoproteolytic cleavage sites within the prosegments of recombinant procathepsin B and procathepsin S. Contribution of a plausible unimolecular autoproteolytic event for the processing of zymogens belonging to the papain

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Stefin B interacts with histones and cathepsin L in the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cysteine proteases bleomycin hydrolase and cathepsin Z mediate N-terminal proteolysis and toxicity of mutant huntingtin

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cathepsins L and Z are critical in degrading polyglutamine-containing proteins within lysosomes

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cysteine Cathepsins Activate ELR Chemokines and Inactivate Non-ELR Chemokines

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Substrate profiling of cysteine proteases using a combinatorial peptide library identifies functionally unique specificities

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Glycosaminoglycans facilitate procathepsin B activation through disruption of propeptide-mature enzyme interactions

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Inhibitors of cathepsin B improve memory and reduce beta-amyloid in transgenic Alzheimer disease mice expressing the wild-type, but not the Swedish mutant, beta-secretase site of the amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cysteine cathepsins trigger caspase-dependent cell death through cleavage of bid and antiapoptotic Bcl-2 homologues

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Lysosomes as "suicide bags" in cell death: myth or reality?

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Proteases: multifunctional enzymes in life and disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

A quantitative proteomics design for systematic identification of protease cleavage events.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Proteomic Identification of Cysteine Cathepsin Substrates Shed from the Surface of Cancer Cells.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Reduced cystatin B activity correlates with enhanced cathepsin activity in progressive myoclonus epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Major histocompatibility complex class II-associated p41 invariant chain fragment is a strong inhibitor of lysosomal cathepsin L

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cathepsin D deficiency is associated with a human neurodegenerative disorder

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cathepsin D deficiency underlies congenital human neuronal ceroid-lipofuscinosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cathepsin D targeted by acid sphingomyelinase-derived ceramide

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Crystal structure of MHC class II-associated p41 Ii fragment bound to cathepsin L reveals the structural basis for differentiation between cathepsins L and S.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

A mutation in the ovine cathepsin D gene causes a congenital lysosomal storage disease with profound neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Lysosomal cysteine proteases: facts and opportunities

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Structure of human dipeptidyl peptidase I (cathepsin C): exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

NF-kappaB protects from the lysosomal pathway of cell death.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

New insights into the molecular basis of progressive myoclonus epilepsy: a multiprotein complex with cystatin B.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Autophagy regulates the processing of amino terminal huntingtin fragments

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cathepsin F mutations cause Type B Kufs disease, an adult-onset neuronal ceroid lipofuscinosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Processing of human cathepsin D is independent of its catalytic function and auto-activation: involvement of cathepsins L and B.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The lysosome: from waste bag to potential therapeutic target

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cathepsin cysteine proteases in cardiovascular disease.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Morphologic and functional correlates of synaptic pathology in the cathepsin D knockout mouse model of congenital neuronal ceroid lipofuscinosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Structure of a Cys25-->Ser mutant of human cathepsin S

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Crystal structure of wild-type human procathepsin K

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Neuroprotective role of γ-enolase in microglia in a mouse model of Alzheimer's disease is regulated by cathepsin X.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Differences in expression patterns of cathepsin C/dipeptidyl peptidase I in normal, pathological and aged mouse central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

1 reference

7 January 2021

Postnatal changes in cathepsin D in rat neural tissue

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Age-dependent changes in the ultrastructure and in the molecular composition of rat brain microtubules.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The distribution of cathepsin D activity in adult and aging human brain regions.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Proteolytic degradation of glutamate decarboxylase mediates disinhibition of hippocampal CA3 pyramidal cells in cathepsin D-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Autocatalytic processing of procathepsin B is triggered by proenzyme activity

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Activation of cathepsin D by glycosaminoglycans.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Crystal structure of human cystatin C stabilized against amyloid formation

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Hereditary cystatin C amyloid angiopathy: genetic, clinical, and pathological aspects

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The role of cystatin C in cerebral amyloid angiopathy and stroke: cell biology and animal models

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Brain extracellular matrix in neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Over-expression of an inactive mutant cathepsin D increases endogenous alpha-synuclein and cathepsin B activity in SH-SY5Y cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Mutations in the gene encoding cystatin B in progressive myoclonus epilepsy (EPM1)

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Inhibitors of lysosomal enzymes: accumulation of lipofuscin-like dense bodies in the brain

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Murine cathepsin F deficiency causes neuronal lipofuscinosis and late-onset neurological disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Lysosomal enzymes and their receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Regulated cell death: signaling and mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Variations in MHC Class II Antigen Processing and Presentation in Health and Disease.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Low-Molecular-Weight Enzyme Inhibitors of Microbial Origin

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Apolipoprotein E in Alzheimer's disease: an update

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Glutamine repeats and neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The epilepsy, the protease inhibitor and the dodecamer: progressive myoclonus epilepsy, cystatin b and a 12-mer repeat expansion.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Changes in cathepsin B and lipofuscin during development and aging in rat brain and heart

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Monitoring compartment-specific substrate cleavage by cathepsins B, K, L, and S at physiological pH and redox conditions

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Phylogenomic analysis of the cystatin superfamily in eukaryotes and prokaryotes

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Reduction of mutant huntingtin accumulation and toxicity by lysosomal cathepsins D and B in neurons

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Acetylation: a new key to unlock tau's role in neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Pseudo-dominant inheritance of a novel CTSF mutation associated with type B Kufs disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cathepsin D deficiency causes juvenile-onset ataxia and distinctive muscle pathology

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Lysosomal cell death at a glance.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Microglial functions and proteases

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Comprehensive search for cysteine cathepsins in the human genome

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Human cathepsin L rescues the neurodegeneration and lethality in cathepsin B/L double-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Lysosomal cysteine cathepsins: signaling pathways in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Revised definition of substrate binding sites of papain-like cysteine proteases

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Regulation of the activity of lysosomal cysteine proteinases by pH-induced inactivation and/or endogenous protein inhibitors, cystatins

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cystatin B deficiency sensitizes neurons to oxidative stress in progressive myoclonus epilepsy, EPM1

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Suppression of cathepsins B and L causes a proliferation of lysosomes and the formation of meganeurites in hippocampus.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Involvement of nitric oxide released from microglia-macrophages in pathological changes of cathepsin D-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cathepsin D deficiency induces persistent neurodegeneration in the absence of Bax-dependent apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Regulating cysteine protease activity: essential role of protease inhibitors as guardians and regulators

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Functions of Propeptide Parts in Cysteine Proteases

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Development of nitrile-based peptidic inhibitors of cysteine cathepsins

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Cystatins: biochemical and structural properties, and medical relevance

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Brain pyroglutamate amyloid-β is produced by cathepsin B and is reduced by the cysteine protease inhibitor E64d, representing a potential Alzheimer's disease therapeutic

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Prolonged In Vivo Retention of a Cathepsin D Targeted Optical Contrast Agent in a Mouse Model of Alzheimer's Disease.

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

The cysteine protease inhibitor, E64d, reduces brain amyloid-β and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, β-secretase activity

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Microglial cell dysregulation in brain aging and neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

Increased expression of stefin B in the nucleus of T98G astrocytoma cells delays caspase activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.ARR.2016.04.010

7 January 2021

10.1016/J.ARR.2016.04.010

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3907371

OpenCitations bibliographic resource ID

3907371

1 reference